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KIZ Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7045267

Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole. More details

$230 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KIZ, Polyclonal Antibody
Full Product Name
KIZ Antibody
Product Gene Name
Product Synonym Names
Centrosomal protein kizuna; Polo-like kinase 1 substrate 1; KIZ; C20orf19; NCRNA00153; PLK1S1; HT013
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
Antigen Affinity Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Molecular Weight
59,243 Da
OMIM
615757
3D Structure
ModBase 3D Structure for Q2M2Z5
Species
Human
Immunogen
Recombinant human Centrosomal protein kizuna protein (N-240AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-85385 / sc-85386
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-KIZ antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-KIZ antibody

Western blot
All lanes: KIZ antibody at 2.41 ug/ml+ Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 76,63,70,74,60 kDa
Observed band size: 75,50 kDa
Rabbit Anti-KIZ Polyclonal Antibody – Cat# MBS7045267

Immunohistochemistry (IHC) of anti-KIZ antibody

Immunohistochemistry of paraffin-embedded human lung tissue using MBS7045267 at dilution of 1:100
Rabbit Anti-KIZ Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS7045267

Immunohistochemistry (IHC) of anti-KIZ antibody

Immunohistochemistry of paraffin-embedded human testis tissue using MBS7045267 at dilution of 1:100
Rabbit Anti-KIZ Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS7045267

Other Notes

Small volumes of anti-KIZ antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KIZ purchase

MBS7045267 is an antibody targeting KIZ. Also known as KIZ Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KIZ. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
centrosomal protein kizuna isoform 2
NCBI Official Synonym Full Names
kizuna centrosomal protein
NCBI Official Symbol
KIZ
NCBI Official Synonym Symbols
RP69; HT013; Kizuna; PLK1S1; C20orf19; NCRNA00153
UniProt Protein Name
Centrosomal protein kizuna
UniProt Synonym Protein Names
Polo-like kinase 1 substrate 1
Protein Family
UniProt Gene Name
KIZ
UniProt Synonym Gene Names
C20orf19; NCRNA00153; PLK1S1
UniProt Entry Name
KIZ_HUMAN
NCBI Protein Information
centrosomal protein kizuna

NCBI Summary for KIZ

The protein encoded by this gene localizes to centrosomes, strengthening and stabilizing the pericentriolar region prior to spindle formation. The encoded protein usually remains with the mother centrosome after centrosomal duplication. Sevral transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]
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UniProt Comments for KIZ

Kizuna: a novel centrosomal protein that, along with the protein kinase Plk1, plays an important role in establishing the mitotic centrosomal architecture during spindle formation and maintaining spindle bipolarity. Its depletion causes centriolar instability during prometaphase which results in multipolar spindles. Four alternatively spliced human isoforms have been reported.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 20p11.23

Cellular Component: centrosome

Molecular Function: protein binding; protein kinase binding

Biological Process: spindle organization and biogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-KIZ antibody

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