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KRT10 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6484197

MBS6484197 is an antibody targeting KRT10. Also known as KRT10, NT (Keratin, Type I Cytoskeletal 10, Cytokeratin-10, CK-10, Keratin-10, K10, KPP) (Biotin). Reactive in Human. Host: Rabbit. More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KRT10, Polyclonal Antibody
Full Product Name
KRT10, NT (Keratin, Type I Cytoskeletal 10, Cytokeratin-10, CK-10, Keratin-10, K10, KPP) (Biotin)
Product Gene Name
anti-KRT10 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity/Purification
Purified by Immunoaffinity chromatography.
Specificity
Recognizes human KRT10.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
58,827 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (38974369..38978863, complement). Location: 17q21
OMIM
113800
3D Structure
ModBase 3D Structure for P13645
Immunogen
Synthetic peptide selected from the N-terminal region of human KRT10 (KLH).
Conjugate
Biotin
Note
Preservative Free

Product Categories/Family for anti-KRT10 antibody

Antibodies; Keratin; Cytokeratin
Applications Tested/Suitable for anti-KRT10 antibody
Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
Application Notes for anti-KRT10 antibody
IHC: 1:50-1:100
ELISA: 1:1,000
WB: 1:100-1:500
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-KRT10 antibody

Western blot analysis of KRT10 Antibody (N-term) in 293 cell line lysates (35ug/lane). KRT10 (arrow) was detected using the purified Pab.
Rabbit Anti-KRT10 Polyclonal Antibody – Cat# MBS6484197

Immunohistochemistry (IHC) of anti-KRT10 antibody

Formalin-fixed and paraffin-embedded human kidney carcinoma with KRT10 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-KRT10 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6484197

Flow Cytometry (FC/FACS) of anti-KRT10 antibody

Flow cytometric analysis of 293 cells using KRT10 Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-KRT10 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS6484197

Product References and Citations for anti-KRT10 antibody

1. Morais, P., Eur J Dermatol 19(4), 333-336 (2009). 2. Barcelos, A.C., J. Cutan. Pathol. 36(6), 647-654 (2009).

Other Notes

Small volumes of anti-KRT10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for KRT10. It may not necessarily be applicable to this product.

NCBI GI #
195972866
NCBI GeneID
3858
NCBI Accession #
NP_000412
UniProt Primary Accession #
P13645
UniProt Secondary Accession #
Q14664; Q8N175
UniProt Related Accession #
P13645
GenBank Nucleotide #
NM_000421
NCBI Official Full Name
keratin, type I cytoskeletal 10
NCBI Official Synonym Full Names
keratin 10
NCBI Official Symbol
KRT10
NCBI Official Synonym Symbols
BIE; EHK; K10; KPP; BCIE; CK10
UniProt Protein Name
Keratin, type I cytoskeletal 10
UniProt Synonym Protein Names
Cytokeratin-10; CK-10; Keratin-10
Protein Family
Keratin
UniProt Gene Name
KRT10
UniProt Synonym Gene Names
KPP; CK-10; K10
UniProt Entry Name
K1C10_HUMAN
NCBI Protein Information
keratin, type I cytoskeletal 10; CK-10; keratin-10; cytokeratin 10

UniProt Comments for KRT10

K10: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of cytoskeletal and microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly. Generally associates with K1.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: extracellular space; membrane; keratin filament; cytoplasm; intermediate filament; nucleus

Molecular Function: structural constituent of epidermis

Biological Process: keratinocyte differentiation

Disease: Erythroderma, Ichthyosiform, Congenital Reticular; Epidermolytic Hyperkeratosis; Ichthyosis, Cyclic, With Epidermolytic Hyperkeratosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KRT10 antibody

 Reference Product  PubMed Publications
 AKT1 antibody  >1 publications with KRT10 and AKT1

Pathways associated with anti-KRT10 antibody

 Products by Pathway  Pathway Diagram
 Staphylococcus Aureus Infection Pathway antibodies  Staphylococcus Aureus Infection Pathway Diagram
 Staphylococcus Aureus Infection Pathway antibodies  Staphylococcus Aureus Infection Pathway Diagram

Diseases associated with anti-KRT10 antibody

 Disease Name  Pubmed Publications
 Hyperkeratosis, Epidermolytic Antibodies  >36 publications with KRT10 and Hyperkeratosis, Epidermolytic
 Neoplasms Antibodies  >28 publications with KRT10 and Neoplasms
 Carcinoma, Squamous Cell Antibodies  >16 publications with KRT10 and Carcinoma, Squamous Cell
 Skin Neoplasms Antibodies  >10 publications with KRT10 and Skin Neoplasms
 Inflammation Antibodies  >9 publications with KRT10 and Inflammation
 Necrosis Antibodies  >5 publications with KRT10 and Necrosis
 Breast Neoplasms Antibodies  >5 publications with KRT10 and Breast Neoplasms
 Disease Models, Animal Antibodies  >4 publications with KRT10 and Disease Models, Animal
 Fibrosis Antibodies  >3 publications with KRT10 and Fibrosis
 Lung Neoplasms Antibodies  >3 publications with KRT10 and Lung Neoplasms

Organs/Tissues associated with anti-KRT10 antibody

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >89 publications with KRT10 and Skin
 Mouth Antibodies  >10 publications with KRT10 and Mouth
 Lung Antibodies  >5 publications with KRT10 and Lung
 Esophagus Antibodies  >2 publications with KRT10 and Esophagus
 Embryonic Tissue Antibodies  >2 publications with KRT10 and Embryonic Tissue
 Ovary Antibodies  >2 publications with KRT10 and Ovary
 Vascular Antibodies  >2 publications with KRT10 and Vascular
 Cervix Antibodies  >1 publications with KRT10 and Cervix
 Eye Antibodies  >1 publications with KRT10 and Eye
 Brain Antibodies  >1 publications with KRT10 and Brain
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