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KRT83 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9609330

Function: There are two types of hair/microfibrillar keratin, I (acidic) and II (neutral to basic).Subunit Structure: Heterotetramer of two type I and two type II keratins.Similarity: Belongs to the intermediate filament family. More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
KRT83, Polyclonal Antibody
Full Product Name
KRT83 Antibody
Product Gene Name
anti-KRT83 antibody
Product Synonym Names
Hair keratin K2.10; Hard keratin, type II, 3; HB 3; HB3; hHb3; K2.10; K83; Keratin 83; Keratin; Keratin, hair, basic, 3; Keratin-83; Krt83; KRT83_HUMAN; KRTHB3; type II cuticular Hb3; Type II hair keratin Hb3; Type-II keratin Kb23; 1; basic; ghHb 1; ghHb1; ghHkb 1; ghHKb1; hair; Hair keratin K2.9; Hard keratin type II 1; HB 1; HB1; hHAKB2 1; K2.9; K81; Keratin 81; Keratin; Keratin hair basic 1; Keratin type II cuticular Hb1; Keratin-81; Keratin81; KRT 81; KRT81; KRT81_HUMAN; KRTHB 1; KRTHB1; Metastatic lymph node 137 gene protein; MLN 137; MLN137; type II cuticular Hb1; Type II hair keratin Hb1; Type-II keratin Kb21; ECTD4; Hair keratin K2.12; Hard keratin type II 5; Hb 5; HB5; hHb5; K12.12; K85; Keratin 85; keratin hair basic 5; Keratin type II cuticular Hb5; keratin, hard, type II; KRTHB5; type II cuticular Hb5; Type II hair keratin Hb5; Type II keratin Kb25; Hair keratin K2.11; Hb6; K86; Keratin; Keratin-86; KRT86; KRT86_HUMAN; KRTHB6; MNX; type II cuticular Hb6; Type II hair keratin Hb6; Type-II keratin Kb26
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Concentration
1mg/ml (lot specific)
Specificity
KRT83 antibody detects endogenous levels of total KRT83
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Antibody/Peptide Pairs
KRT83 peptide (MBS9628034) is used for blocking the activity of KRT83 antibody (MBS9609330)
Molecular Weight
Observed: 55 kDa
Predicted: 55 kDa
3D Structure
ModBase 3D Structure for P78385
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Immunogen
A synthesized peptide derived from human KRT83
Tissue Specificity
Synthesis begins in the cortex 10-15 cell layers above the apex of the dermal papilla and ends abruptly in the middle of the cortex.
Conjugation
Unconjugated
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-KRT83 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-KRT83 antibody
WB: 1:1000-3000

Western Blot (WB) of anti-KRT83 antibody

Western blot analysis of KRT83 using HepG2 whole cell lysates
Rabbit Anti-KRT83 Polyclonal Antibody – Cat# MBS9609330

Other Notes

Small volumes of anti-KRT83 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KRT83 purchase

MBS9609330 is an antibody targeting KRT83. Also known as KRT83 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KRT83. It may not necessarily be applicable to this product.

NCBI GI #
169790841
NCBI GeneID
3889
NCBI Accession #
NP_002273.3
UniProt Primary Accession #
P78385
UniProt Secondary Accession #
Q6NT21; Q9NSB3; A1A4S9; B2RC21
UniProt Related Accession #
P78385
GenBank Nucleotide #
NM_002282.3
NCBI Official Full Name
keratin, type II cuticular Hb3
NCBI Official Synonym Full Names
keratin 83
NCBI Official Symbol
KRT83
NCBI Official Synonym Symbols
HB3; Hb-3; EKVP5; MNLIX; KRTHB3
UniProt Protein Name
Keratin, type II cuticular Hb3
UniProt Synonym Protein Names
Hair keratin K2.10; Keratin-83; K83; Type II hair keratin Hb3; Type-II keratin Kb23
Protein Family
Keratin
UniProt Gene Name
KRT83
UniProt Synonym Gene Names
KRTHB3; K83
NCBI Protein Information
keratin, type II cuticular Hb3

NCBI Summary for KRT83

The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB6, is found primarily in the hair cortex. [provided by RefSeq, Jul 2008]
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UniProt Comments for KRT83

MiscellaneousThere are two types of hair/microfibrillar keratin, I (acidic) and II (neutral to basic).

Research Articles on KRT83

1. Our findings indicate that at least some cases of autosomal recessive Progressive symmetric erythrokeratoderma (PSEK)and autosomal dominant monilethrix are allelic, respectively resulting from loss-of-function and missense mutations in the KRT83 gene

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KRT83 antibody

 Reference Product  PubMed Publications
 DSG4 antibody  >2 publications with KRT83 and DSG4

Diseases associated with anti-KRT83 antibody

 Disease Name  Pubmed Publications
 Monilethrix Antibodies  >5 publications with KRT83 and Monilethrix
 Urologic Neoplasms Antibodies  >1 publications with KRT83 and Urologic Neoplasms
 Neoplasms Antibodies  >1 publications with KRT83 and Neoplasms
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