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KRTAP1-1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6008104

KRTAP1-1 is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and… More details

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Product Overview

Online Datasheet in PDF
Product Name
KRTAP1-1, Polyclonal Antibody
Full Product Name
KRTAP1-1, ID (KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1, Keratin-associated protein 1-1, High sulfur keratin-associated protein 1.1, Keratin-associated protein 1.1, Keratin-associated protein 1.6, Keratin-associated protein 1.7)
Product Gene Name
anti-KRTAP1-1 antibody
Product Synonym Names
Anti -KRTAP1-1, ID (KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1, Keratin-associated protein 1-1, High sulfur keratin-associated protein 1.1, Keratin-associated protein 1.1, Keratin-associated protein 1.6, Keratin-associated protein 1.7)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
18,235 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (39196811..39197713, complement). Location: 17q12
OMIM
608819
3D Structure
ModBase 3D Structure for Q07627
Immunogen
KRTAP1-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-125 amino acids from the Central region of human KRTAP1-1.

Product Categories/Family for anti-KRTAP1-1 antibody

Antibodies; Abs to Keratin; Cytokeratin
Applications Tested/Suitable for anti-KRTAP1-1 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes for anti-KRTAP1-1 antibody
Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Flow Cytometry: 1:10-50

Western Blot (WB) of anti-KRTAP1-1 antibody

Western blot analysis of KRTAP1-1 Antibody (Center) in K562 cell line lysates (35ug/lane).KRTAP1-1 (arrow) was detected using the purified Pab.
Rabbit Anti-KRTAP1-1 Polyclonal Antibody – Cat# MBS6008104

Immunohistochemistry (IHC) of anti-KRTAP1-1 antibody

KRTAP1-1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the KRTAP1-1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-KRTAP1-1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6008104

Flow Cytometry (FC/FACS) of anti-KRTAP1-1 antibody

KRTAP1-1 Antibody (Center) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-KRTAP1-1 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS6008104

Other Notes

Small volumes of anti-KRTAP1-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KRTAP1-1 purchase

MBS6008104 is an antibody targeting KRTAP1-1. Also known as KRTAP1-1, ID (KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1, Keratin-associated protein 1-1, High sulfur keratin-associated protein 1.1, Keratin-associated protein 1.1, Keratin-associated protein 1.6, Keratin-associated protein 1.7). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KRTAP1-1. It may not necessarily be applicable to this product.

NCBI GI #
13569942
NCBI GeneID
81851
NCBI Accession #
NP_112229.1
UniProt Primary Accession #
Q07627
UniProt Secondary Accession #
Q96S60; Q96S67; A6NC32
UniProt Related Accession #
Q07627
GenBank Nucleotide #
NM_030967.2
NCBI Official Full Name
keratin-associated protein 1-1
NCBI Official Synonym Full Names
keratin associated protein 1-1
NCBI Official Symbol
KRTAP1-1
NCBI Official Synonym Symbols
HB2A; KAP1.1; KAP1.6; KAP1.7; KAP1.1A; KAP1.1B; KRTAP1A; hKAP1.7; KRTAP1.1
UniProt Protein Name
Keratin-associated protein 1-1
UniProt Synonym Protein Names
High sulfur keratin-associated protein 1.1; Keratin-associated protein 1.1; Keratin-associated protein 1.6; Keratin-associated protein 1.7
Protein Family
Keratin-associated protein
UniProt Gene Name
KRTAP1-1
UniProt Synonym Gene Names
B2A; KAP1.1; KAP1.6; KAP1.7; KRTAP1.1
UniProt Entry Name
KRA11_HUMAN
NCBI Protein Information
keratin-associated protein 1-1; keratin associated protein 1A; keratin associated protein 1.7; keratin-associated protein 1.6; keratin-associated protein 1.7; high sulfur keratin-associated protein 1.1

NCBI Summary for KRTAP1-1

This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the high sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008]
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UniProt Comments for KRTAP1-1

KRTAP1-1: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. Belongs to the KRTAP type 1 family. Interacts with hair keratins

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: keratin filament
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Research Articles on KRTAP1-1

1. polymorphisms in Japanese and Caucasian individuals

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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