Rabbit Anti-LALBA Polyclonal Antibody – Cat# MBS648410

Lactalbumin, Alpha (LALBA) Antibody – Rabbit Polyclonal

Name: LALBA Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS648410
Price: 905 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS648410

Alpha-lactalbumin is one of the major proteins in the alpha region after immunoelectrophoresis of human milk. It has been implicated as a component of the enzyme lactose synthetase which catalyzes the formation of lactose from uridine diphosphate galactose… More details

$905 / 1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Lactalbumin, alpha (LALBA), Polyclonal Antibody

Full Product Name

Lactalbumin, alpha (Alpha-Lactalbumin, LALBA, Lactose Synthase B Protein, Lysozyme-like Protein 7, LYZL7, MGC138521, MGC138523) (HRP)

Product Gene Name

anti-LALBA antibody

Product Synonym Names

Anti -Lactalbumin, alpha (Alpha-Lactalbumin, LALBA, Lactose Synthase B Protein, Lysozyme-like Protein 7, LYZL7, MGC138521, MGC138523) (HRP)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a lyophilized powder from PBS, pH 7.2. Labeled with Horseradish Peroxidase (HRP). Reconstitute in 1ml sterile ddH2O. Dilute further in PBS, pH 7.2.

Purity/Purification

Highly Purified
Purified by DEAE chromatography.

Specificity

Recognizes human alpha-lactalbumin. Alpha-lactalbumin is found in human milk and in udder tissue No reaction observed when tested against serum in immunoelectrophoresis and double radial immunodiffusion.

Preparation and Storage

Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Labeled with horseradish peroxidase (HRP). Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. HRP conjugates are sensitive to light.

Molecular Weight

16,225 Da

Chromosome Location

Chromosome: 12; NC_000012.11 (48961467..48963829, complement). Location: 12q13

OMIM

149750

3D Structure

ModBase 3D Structure for P00709

Immunogen

Highly purified alpha-lactalbumin isolated from human milk

Product Categories/Family for anti-LALBA antibody

Antibodies; Abs to Albumin

Applications Tested/Suitable for anti-LALBA antibody

ELISA (EL/EIA)

Application Notes for anti-LALBA antibody

Suitable for use in ELISA.

Other Notes

Small volumes of anti-LALBA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LALBA purchase

MBS648410 is an antibody targeting LALBA. Also known as Lactalbumin, alpha (Alpha-Lactalbumin, LALBA, Lactose Synthase B Protein, Lysozyme-like Protein 7, LYZL7, MGC138521, MGC138523) (HRP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LALBA. It may not necessarily be applicable to this product.

NCBI GI #

119578394

NCBI GeneID

3906

NCBI Accession #

EAW57990.1

UniProt Primary Accession #

P00709

UniProt Secondary Accession #

Q6FGX0; Q9UDK4

UniProt Related Accession #

P00709

NCBI Official Full Name

lactalbumin, alpha-

NCBI Official Synonym Full Names

lactalbumin, alpha-

NCBI Official Symbol

LALBA

UniProt Protein Name

Alpha-lactalbumin

UniProt Synonym Protein Names

Lactose synthase B protein; Lysozyme-like protein 7

Protein Family

Alpha-lactalbumin

UniProt Gene Name

LALBA

UniProt Synonym Gene Names

LYZL7

UniProt Entry Name

LALBA_HUMAN

NCBI Protein Information

alpha-lactalbumin; lysozyme-like protein 7; lactose synthase B protein

NCBI Summary for LALBA

This gene encodes alpha-lactalbumin, a principal protein of milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta 1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transfering galactose moieties to glucose. As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of alpha-lactalbumin, called HAMLET, likely induces apoptosis in tumor and immature cells. [provided by RefSeq, Jul 2008]

UniProt Comments for LALBA

Function: Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.

Subunit structure: Lactose synthase (LS) is a heterodimer of a catalytic component, beta1,4-galactosyltransferase (beta4Gal-T1) and a regulatory component, alpha-lactalbumin (LA).

Subcellular location: Secreted.

Tissue specificity: Mammary gland specific. Secreted in milk.

Sequence similarities: Belongs to the glycosyl hydrolase 22 family.

Research Articles on LALBA

1. High molecular mass complexes are formed with alpha-lactalbumin and alphaB-crystallin, preventing the amorphous aggregation of alpha-lactalbumin.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LALBA antibody

Reference Product	PubMed Publications
CSN2 antibody	>8 publications with LALBA and CSN2
CSN1S1 antibody	>1 publications with LALBA and CSN1S1
B4GALT1 antibody	>1 publications with LALBA and B4GALT1

Pathways associated with anti-LALBA antibody

Products by Pathway	Pathway Diagram
Galactose Metabolism Pathway antibodies	Galactose Metabolism Pathway Diagram
Galactose Metabolism Pathway antibodies	Galactose Metabolism Pathway Diagram

Diseases associated with anti-LALBA antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>2 publications with LALBA and Inflammation
Necrosis Antibodies	>1 publications with LALBA and Necrosis

Organs/Tissues associated with anti-LALBA antibody

Organ/Tissue Name	Pubmed Publications
Mixed Antibodies	>1 publications with LALBA and Mixed