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LAMTOR5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7045297

As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the… More details

$230 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
LAMTOR5, Polyclonal Antibody
Full Product Name
LAMTOR5 Antibody
Product Gene Name
Product Synonym Names
Ragulator complex protein LAMTOR5; Hepatitis B virus X-interacting protein; HBV X-interacting protein; HBX-interacting protein; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5; LAMTOR5; HBXIP; XIP
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
Antigen Affinity Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Molecular Weight
9,614 Da
OMIM
608521
3D Structure
ModBase 3D Structure for O43504
Species
Human
Immunogen
Recombinant human Ragulator complex protein LAMTOR5 protein (1-173AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-54080 / sc-54083
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-LAMTOR5 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-LAMTOR5 antibody
Recommended dilution: IHC: 1:20-1:200

Immunohistochemistry (IHC) of anti-LAMTOR5 antibody

Immunohistochemistry of paraffin-embedded human liver cancer using MBS7045297 at dilution 1:100
Rabbit Anti-LAMTOR5 Polyclonal Antibody – Cat# MBS7045297

Immunohistochemistry (IHC) of anti-LAMTOR5 antibody

Immunohistochemistry of paraffin-embedded human breast cancer using MBS7045297 at dilution 1:100
Rabbit Anti-LAMTOR5 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS7045297

Other Notes

Small volumes of anti-LAMTOR5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LAMTOR5 purchase

MBS7045297 is an antibody targeting LAMTOR5. Also known as LAMTOR5 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LAMTOR5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ragulator complex protein LAMTOR5
NCBI Official Synonym Full Names
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
NCBI Official Symbol
LAMTOR5
NCBI Official Synonym Symbols
XIP; HBXIP
UniProt Protein Name
Ragulator complex protein LAMTOR5
UniProt Synonym Protein Names
Hepatitis B virus X-interacting protein; HBV X-interacting protein; HBX-interacting protein; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5
UniProt Gene Name
LAMTOR5
UniProt Synonym Gene Names
HBXIP; XIP; HBV X-interacting protein; HBX-interacting protein
UniProt Entry Name
LTOR5_HUMAN
NCBI Protein Information
ragulator complex protein LAMTOR5

NCBI Summary for LAMTOR5

This gene encodes a protein that specifically complexes with the C-terminus of hepatitis B virus X protein (HBx). The function of this protein is to negatively regulate HBx activity and thus to alter the replication life cycle of the virus. [provided by RefSeq, Jul 2008]

UniProt Comments for LAMTOR5

HBXIP: When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway. Down-regulates hepatitis B virus (HBV) replication. Belongs to the HBXIP family.

Protein type: DNA replication; Apoptosis

Chromosomal Location of Human Ortholog: 1p13.3

Cellular Component: cytosol; lysosomal membrane; lysosome

Molecular Function: guanyl-nucleotide exchange factor activity; protein binding; protein complex scaffold

Biological Process: cell cycle arrest; macroautophagy; negative regulation of apoptosis; negative regulation of caspase activity; positive regulation of TOR signaling pathway; regulation of cell size; response to virus
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-LAMTOR5 antibody

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