• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

LAX1 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS422130

MBS422130 is an antibody targeting LAX1. Also known as Goat anti-LAX1 Antibody. Reactive in Expected from sequence similarity: Human. Host: Goat. More details

$305 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LAX1, Polyclonal Antibody
Full Product Name
Goat anti-LAX1 Antibody
Product Gene Name
Product Synonym Names
Goat Anti-LAX Antibody; LAX1; lymphocyte transmembrane adaptor 1; FLJ20340; LAX; LAT-like membrane associated protein; OTTHUMP00000034094; linker for activation of x cells; LAX1 antibody; lymphocyte transmembrane adaptor 1 antibody; FLJ20340 antibody; LAX antibody; LAT-like membrane associated protein antibody; OTTHUMP00000034094 antibody; linker for activation of x cells antibody
Immunogen Sequence
NLTPSAHCIN VRAS
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Human
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
LAX1 peptide (MBS426797) is used for blocking the activity of LAX1 antibody (MBS422130)
Molecular Weight
42,491 Da
Immunogen
Peptide with sequence NLTPSAHCINVRAS, from the internal region of the protein sequence according to NP_060243.2; NP_001129662.1.
Epitope
Internal region
Note
This antibody is expected to recognize both reported isoforms (NP_060243.2; NP_001129662.1).
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-LAX1 antibody
Peptide ELISA (EIA)
Application Notes for anti-LAX1 antibody
Peptide ELISA: Antibody detection limit dilution 1: 1000.
Western Blot: Preliminary experiments in lysates of Peripheral Blood Mononucleocytes and of cell lines HeLa and MOLT4 gave no specific signal but low background (at antibody concentration up to 1ug/ml).

Other Notes

Small volumes of anti-LAX1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LAX1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
lymphocyte transmembrane adapter 1 isoform a
NCBI Official Synonym Full Names
lymphocyte transmembrane adaptor 1
NCBI Official Symbol
LAX1
NCBI Official Synonym Symbols
LAX
UniProt Protein Name
Lymphocyte transmembrane adapter 1
UniProt Synonym Protein Names
Linker for activation of X cells; Membrane-associated adapter protein LAX
UniProt Gene Name
LAX1
UniProt Synonym Gene Names
LAX
UniProt Entry Name
LAX1_HUMAN
NCBI Protein Information
lymphocyte transmembrane adapter 1

UniProt Comments for LAX1

LAX1: Negatively regulates TCR (T-cell antigen receptor)- mediated signaling in T-cells and BCR (B-cell antigen receptor)- mediated signaling in B-cells. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: cytoplasm; Golgi apparatus; integral to membrane; lipid raft; membrane; plasma membrane

Molecular Function: protein binding; protein kinase binding; SH2 domain binding

Biological Process: adaptive immune response; antigen receptor-mediated signaling pathway; B cell activation; immune response; immunoglobulin secretion; inactivation of MAPK activity; negative regulation of T cell activation
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000