Rabbit Anti-LHX8 Polyclonal Antibody – Cat# MBS6316016

LHX8 Antibody – Rabbit Polyclonal

Name: LHX8 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6316016
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6316016

Members of the LIM homeobox gene family, such as LHX8, encode transcription regulators that share common structural features. They all contain 2 tandemly repeated cysteine-rich double-zinc finger motifs, called LIM domains, in addition to a homeodomain. The… More details

$1060 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LHX8, Polyclonal Antibody

Full Product Name

LHX8, ID (LHX8, LIM/homeobox protein Lhx8) (MaxLight 550)

Product Gene Name

anti-LHX8 antibody

Product Synonym Names

LHX8; LIM/homeobox protein Lhx8

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

38,170 Da

OMIM

604425

3D Structure

ModBase 3D Structure for Q68G74

Immunogen

LHX8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-232 amino acids from the Central region of human LHX8.

Conjugate

MaxLight550

Note

Preservative Free

Product Categories/Family for anti-LHX8 antibody

Antibodies; Transcription Factors; Zinc; Ring; Homeobox

Applications Tested/Suitable for anti-LHX8 antibody

Western Blot (WB), FLISA

Application Notes for anti-LHX8 antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-LHX8 antibody

Nikopensius, T., et al. Birth Defects Res. Part A Clin. Mol. Teratol. 88(9):748-756(2010). Jagomagi, T., et al. Eur. J. Oral Sci. 118(3):213-220(2010). Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010): Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008). Qin, Y., et al. Fertil. Steril. 89(4):1012-1014(2008).

Other Notes

Small volumes of anti-LHX8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LHX8 purchase

MBS6316016 is an antibody targeting LHX8. Also known as LHX8, ID (LHX8, LIM/homeobox protein Lhx8) (MaxLight 550). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LHX8. It may not necessarily be applicable to this product.

NCBI GI #

50083287

NCBI GeneID

431707

NCBI Accession #

NP_001001933.1

UniProt Primary Accession #

Q68G74

UniProt Secondary Accession #

E9PGE3

UniProt Related Accession #

Q68G74

GenBank Nucleotide #

NM_001001933.1

NCBI Official Full Name

LIM/homeobox protein Lhx8 isoform 1

NCBI Official Synonym Full Names

LIM homeobox 8

NCBI Official Symbol

LHX8

NCBI Official Synonym Symbols

LHX7

UniProt Protein Name

LIM/homeobox protein Lhx8

Protein Family

LIM/homeobox protein

UniProt Gene Name

LHX8

UniProt Synonym Gene Names

LIM homeobox protein 8

UniProt Entry Name

LHX8_HUMAN

NCBI Protein Information

LIM/homeobox protein Lhx8; LIM-homeodomain protein Lhx8

NCBI Summary for LHX8

The protein encoded by this gene is a member of the LIM homeobox family of proteins, which are involved in patterning and differentiation of various tissue types. These proteins contain two tandemly repeated cysteine-rich double-zinc finger motifs known as LIM domains, in addition to a DNA-binding homeodomain. This family member is a transcription factor that plays a role in tooth morphogenesis. It is also involved in oogenesis and in neuronal differentiation. This gene is a candidate gene for cleft palate, and it is also associated with odontoma formation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]

UniProt Comments for LHX8

LHX8: Transcription factor involved in differentiation of certain neurons and mesenchymal cells.

Protein type: DNA-binding; Transcription factor; Cell development/differentiation

Chromosomal Location of Human Ortholog: 1p31.1

Cellular Component: female germ cell nucleus

Molecular Function: zinc ion binding; sequence-specific DNA binding

Biological Process: learning and/or memory; regulation of transcription, DNA-dependent; transcription, DNA-dependent; forebrain neuron development; female gonad development; odontogenesis of dentine-containing teeth

Research Articles on LHX8

1. Increasing Lhx8 expression in neuronal cell lines also increased acetylcholine release.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LHX8 antibody

Reference Product	PubMed Publications
NOBOX antibody	>10 publications with LHX8 and NOBOX
FIGLA antibody	>8 publications with LHX8 and FIGLA
SOHLH1 antibody	>5 publications with LHX8 and SOHLH1
SATB2 antibody	>1 publications with LHX8 and SATB2
GBX1 antibody	>1 publications with LHX8 and GBX1

Diseases associated with anti-LHX8 antibody

Disease Name	Pubmed Publications
Cleft Palate Antibodies	>9 publications with LHX8 and Cleft Palate
Congenital Abnormalities Antibodies	>7 publications with LHX8 and Congenital Abnormalities
Disease Models, Animal Antibodies	>2 publications with LHX8 and Disease Models, Animal
Inflammation Antibodies	>2 publications with LHX8 and Inflammation
Hypertension Antibodies	>1 publications with LHX8 and Hypertension
Abnormalities, Multiple Antibodies	>1 publications with LHX8 and Abnormalities, Multiple
Necrosis Antibodies	>1 publications with LHX8 and Necrosis

Organs/Tissues associated with anti-LHX8 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>17 publications with LHX8 and Brain
Embryonic Tissue Antibodies	>10 publications with LHX8 and Embryonic Tissue
Connective Tissue Antibodies	>3 publications with LHX8 and Connective Tissue
Testis Antibodies	>1 publications with LHX8 and Testis
Skin Antibodies	>1 publications with LHX8 and Skin