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LINGO Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6316335

LINGO-1 (LRR and Ig domain-containing Nogo Receptor interating protein) is a nervous system-specific LRR-Ig-containing protein with an important role in CNS biology. LINGO-1 was discovered in a sequence database search for human SLIT homologs that were… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
LINGO, Polyclonal Antibody
Full Product Name
LINGO, Phosphorylated (1, Phosphorylated (pS596) (LRRN6A, Lingo1, Lern1, Lrrn6a, Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1, Leucine-rich repeat neuronal protein 1, Leucine-rich repeat neuronal protei
Product Gene Name
anti-LINGO antibody
Product Synonym Gene Name
Lingo1
Product Synonym Names
LRRN6A; Lingo1; Lern1; Lrrn6a; Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; Leucine-rich repeat neuronal protein 1; Leucine-rich repeat neuronal protein 6A
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
69,101 Da
3D Structure
ModBase 3D Structure for Q9D1T0
Immunogen
Phospho-LINGO-1(LRRN6A)-pS596 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 582~611 amino acids surrounding pS596 of human LINGO-1(LRRN6A).
Conjugate
MaxLight550
Antigen Modification
Phosphorylated
Note
Preservative Free

Product Categories/Family for anti-LINGO antibody

Antibodies; Receptors
Applications Tested/Suitable for anti-LINGO antibody
FLISA, Dot Blot (DB)
Application Notes for anti-LINGO antibody
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-LINGO antibody

Mandai, K., et.al., Neuron 63 (5), 614-627 (2009). Homma, S., et.al., Gene Expr. Patterns 9 (1), 1-26 (2009).

Other Notes

Small volumes of anti-LINGO antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LINGO purchase

MBS6316335 is an antibody targeting LINGO. Also known as LINGO, Phosphorylated (1, Phosphorylated (pS596) (LRRN6A, Lingo1, Lern1, Lrrn6a, Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1, Leucine-rich repeat neuronal protein 1, Leucine-rich repeat neuronal protei. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LINGO. It may not necessarily be applicable to this product.

NCBI GI #
30841016
NCBI GeneID
235402
NCBI Accession #
NP_851419.1
UniProt Primary Accession #
Q9D1T0
UniProt Secondary Accession #
Q3TQJ4; Q6VVF9; Q7TT38
UniProt Related Accession #
Q9D1T0
GenBank Nucleotide #
NM_181074.4
NCBI Official Full Name
leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
NCBI Official Synonym Full Names
leucine rich repeat and Ig domain containing 1
NCBI Official Symbol
Lingo1
NCBI Official Synonym Symbols
LERN1; Lrrn6a; UNQ201; LINGO-1; AV148400; 4930471K13Rik
UniProt Protein Name
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
UniProt Synonym Protein Names
Leucine-rich repeat neuronal protein 1; Leucine-rich repeat neuronal protein 6A
UniProt Gene Name
Lingo1
UniProt Synonym Gene Names
Lern1; Lrrn6a
UniProt Entry Name
LIGO1_MOUSE
NCBI Protein Information
leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; leucine rich repeat neuronal 6A; leucine-rich repeat neuronal 6A; leucine-rich repeat neuronal protein 1; leucine-rich repeat neuronal protein 6A

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-LINGO antibody

 Products by Pathway  Pathway Diagram
 Axonal Growth Inhibition (RHOA Activation) Pathway antibodies  Axonal Growth Inhibition (RHOA Activation) Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signalling By NGF Pathway antibodies  Signalling By NGF Pathway Diagram
 MRNA Processing Pathway antibodies  MRNA Processing Pathway Diagram
 P75 NTR Receptor-mediated Signalling Pathway antibodies  P75 NTR Receptor-mediated Signalling Pathway Diagram
 P75NTR Regulates Axonogenesis Pathway antibodies  P75NTR Regulates Axonogenesis Pathway Diagram

Diseases associated with anti-LINGO antibody

 Disease Name  Pubmed Publications
 Essential Tremor Antibodies  >27 publications with LINGO and Essential Tremor
 Inflammation Antibodies  >2 publications with LINGO and Inflammation

Organs/Tissues associated with anti-LINGO antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >23 publications with LINGO and Brain
 Spinal Cord Antibodies  >11 publications with LINGO and Spinal Cord
 Dorsal Root Ganglion Antibodies  >5 publications with LINGO and Dorsal Root Ganglion
 Embryonic Tissue Antibodies  >5 publications with LINGO and Embryonic Tissue
 Eye Antibodies  >4 publications with LINGO and Eye
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