• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

MVP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6007593

MVP, the major vault protein, is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in… More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LRP (MVP), Polyclonal Antibody
Full Product Name
LRP, CT (Major Vault Protein, Lung Resistance-related Protein, MVP)
Product Gene Name
anti-MVP antibody
Product Synonym Names
Anti -LRP, CT (Major Vault Protein, Lung Resistance-related Protein, MVP)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human MVP.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
99,327 Da
OMIM
605088
3D Structure
ModBase 3D Structure for Q14764
Immunogen
Synthetic peptide selected from the C-terminal region of human MVP (KLH).

Product Categories/Family for anti-MVP antibody

Antibodies; Abs to Multi Drug Resistance (MDR)
Applications Tested/Suitable for anti-MVP antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-MVP antibody
Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100

Western Blot (WB) of anti-MVP antibody

The anti-MVP C-term Antibody is used in Western blot to detect MVP in A375 lysate.
Rabbit Anti-MVP Polyclonal Antibody – Cat# MBS6007593

Western Blot (WB) of anti-MVP antibody

Western blot analysis of MVP (arrow) using rabbit polyclonal MVP C-term Antibody . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MVP gene (Lane 2) (Origene Technologies).
Rabbit Anti-MVP Polyclonal Antibody, Western Blot (WB) – Cat# MBS6007593

Immunohistochemistry (IHC) of anti-MVP antibody

Formalin-fixed and paraffin-embedded human lung carcinoma with MVP Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-MVP Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6007593

Flow Cytometry (FC/FACS) of anti-MVP antibody

Flow cytometric analysis of NCI-H292 cells using MVP Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-MVP Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS6007593

Other Notes

Small volumes of anti-MVP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MVP purchase

MBS6007593 is an antibody targeting MVP. Also known as LRP, CT (Major Vault Protein, Lung Resistance-related Protein, MVP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MVP. It may not necessarily be applicable to this product.

NCBI GI #
19577290
NCBI Accession #
CAA56256.2
UniProt Primary Accession #
Q14764
UniProt Secondary Accession #
Q96BG4; Q9BPW6; Q9BQT1; Q9UBD1
NCBI Official Full Name
lrp
UniProt Protein Name
Major vault protein
UniProt Synonym Protein Names
Lung resistance-related protein
Protein Family
Hyperpolarization-activated voltage-gated potassium channel
UniProt Gene Name
MVP
UniProt Synonym Gene Names
LRP; MVP
UniProt Entry Name
MVP_HUMAN

UniProt Comments for MVP

MVP: Required for normal vault structure. Vaults are multi- subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo- cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: cytoskeleton; membrane; perinuclear region of cytoplasm; cytoplasm; nuclear pore; ribonucleoprotein complex; nucleus

Molecular Function: protein binding; protein kinase binding; protein phosphatase binding

Biological Process: cell proliferation; protein transport; mRNA transport; negative regulation of protein amino acid autophosphorylation
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MVP antibody

 Reference Product  PubMed Publications
 ABCB1 antibody  >40 publications with MVP and ABCB1
 ABCC1 antibody  >7 publications with MVP and ABCC1
 PTEN antibody  >5 publications with MVP and PTEN
 ABCC3 antibody  >4 publications with MVP and ABCC3
 STAT1 antibody  >2 publications with MVP and STAT1
 PTPN11 antibody  >1 publications with MVP and PTPN11
 YPEL4 antibody  >1 publications with MVP and YPEL4

Diseases associated with anti-MVP antibody

 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >736 publications with MVP and Heart Diseases
 Neoplasms Antibodies  >283 publications with MVP and Neoplasms
 Brain Diseases Antibodies  >75 publications with MVP and Brain Diseases
 Neoplasm Metastasis Antibodies  >32 publications with MVP and Neoplasm Metastasis
 Fibrosis Antibodies  >30 publications with MVP and Fibrosis
 Hypertension Antibodies  >29 publications with MVP and Hypertension
 Hypertrophy Antibodies  >29 publications with MVP and Hypertrophy
 Disease Models, Animal Antibodies  >29 publications with MVP and Disease Models, Animal
 Myocardial Infarction Antibodies  >26 publications with MVP and Myocardial Infarction
 Neurobehavioral Manifestations Antibodies  >23 publications with MVP and Neurobehavioral Manifestations

Organs/Tissues associated with anti-MVP antibody

 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >524 publications with MVP and Heart
 Blood Antibodies  >253 publications with MVP and Blood
 Lung Antibodies  >208 publications with MVP and Lung
 Vascular Antibodies  >97 publications with MVP and Vascular
 Brain Antibodies  >77 publications with MVP and Brain
 Muscle Antibodies  >62 publications with MVP and Muscle
 Bone Antibodies  >56 publications with MVP and Bone
 Connective Tissue Antibodies  >43 publications with MVP and Connective Tissue
 Liver Antibodies  >32 publications with MVP and Liver
 Bladder Antibodies  >29 publications with MVP and Bladder
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000