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LRRC38 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6317101

Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Modulates gating properties by producing a marked shift in the BK channel's voltage dependence of activation in the hyperpolarizing direction, and in the… More details

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Product Overview

Online Datasheet in PDF
Product Name
LRRC38, Polyclonal Antibody
Full Product Name
LRRC38, CT (LRRC38, Leucine-rich repeat-containing protein 38, BK channel auxilliary gamma subunit LRRC38) (FITC)
Product Gene Name
anti-LRRC38 antibody
Product Synonym Names
LRRC38; Leucine-rich repeat-containing protein 38; BK channel auxilliary gamma subunit LRRC38
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human LRRC38.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
32,082 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (13801445..13840242, complement). Location: 1p36.21
OMIM
615212
3D Structure
ModBase 3D Structure for Q5VT99
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 188-216 in the C-terminal region of human LRRC38, UniProt Accession #Q5VT99. Cellular Localization: Cell membrane, Single-pass 1 membrane protein
Conjugate
FITC
Note
Preservative Free
Special Handling
Light sensitive

Product Categories/Family for anti-LRRC38 antibody

Antibodies; Leucine-rich Proteins
Applications Tested/Suitable for anti-LRRC38 antibody
Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes for anti-LRRC38 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-LRRC38 antibody

Western Blot analysis NCI-H460 cell line lysates (35ug/lane) usingMBS642090. This demonstrates the LRRC38 antibody detected the LRRC38 protein (arrow).
Rabbit Anti-LRRC38 Polyclonal Antibody – Cat# MBS6317101

Immunohistochemistry (IHC) of anti-LRRC38 antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue using 037954followed by peroxidase conjugation of the secondary antibody and DAB staining.
Rabbit Anti-LRRC38 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6317101

Flow Cytometry (FC/FACS) of anti-LRRC38 antibody

Flow cytometric analysis of NCI-H460 cells (right histogram) using MBS642090 compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-LRRC38 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS6317101

Product References and Citations for anti-LRRC38 antibody

Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002).

Other Notes

Small volumes of anti-LRRC38 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LRRC38 purchase

MBS6317101 is an antibody targeting LRRC38. Also known as LRRC38, CT (LRRC38, Leucine-rich repeat-containing protein 38, BK channel auxilliary gamma subunit LRRC38) (FITC). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LRRC38. It may not necessarily be applicable to this product.

NCBI GI #
299782601
NCBI GeneID
126755
NCBI Accession #
NP_001010847.1
UniProt Primary Accession #
Q5VT99
UniProt Secondary Accession #
Q96B32
UniProt Related Accession #
Q5VT99
GenBank Nucleotide #
NM_001010847.1
NCBI Official Full Name
leucine-rich repeat-containing protein 38
NCBI Official Synonym Full Names
leucine rich repeat containing 38
NCBI Official Symbol
LRRC38
NCBI Official Synonym Symbols
RP4-597A16.1
UniProt Protein Name
Leucine-rich repeat-containing protein 38
UniProt Synonym Protein Names
BK channel auxiliary gamma subunit LRRC38
Protein Family
Leucine-rich repeat-containing protein
UniProt Gene Name
LRRC38
UniProt Entry Name
LRC38_HUMAN
NCBI Protein Information
leucine-rich repeat-containing protein 38; BK channel auxiliary gamma subunit LRRC38; BK channel auxilliary gamma subunit LRRC38

UniProt Comments for LRRC38

LRRC38: Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Modulates gating properties by producing a marked shift in the BK channel's voltage dependence of activation in the hyperpolarizing direction, and in the absence of calcium.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p36.21

Cellular Component: integral to membrane; plasma membrane

Biological Process: ion transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-LRRC38 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with LRRC38 and Brain
 Muscle Antibodies  >1 publications with LRRC38 and Muscle
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