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LSD1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6317450

MBS6317450 is an antibody targeting LSD1. Also known as LSD1, CT (KDM1A, AOF2, KDM1, KIAA0601, LSD1, Lysine-specific histone demethylase 1A, BRAF35-HDAC complex protein BHC110, Flavin-containing amine oxidase domain-containing protein 2) (AP). Reactive in… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LSD1, Polyclonal Antibody
Full Product Name
LSD1, CT (KDM1A, AOF2, KDM1, KIAA0601, LSD1, Lysine-specific histone demethylase 1A, BRAF35-HDAC complex protein BHC110, Flavin-containing amine oxidase domain-containing protein 2) (AP)
Product Gene Name
anti-LSD1 antibody
Product Synonym Gene Name
KDM1A
Product Synonym Names
KDM1A; AOF2; KDM1; KIAA0601; LSD1; Lysine-specific histone demethylase 1A; BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase.
Purity/Purification
Purified by Protein A/G Affinity Chromatography.
Specificity
Recognizes human LSD1.
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
852
Chromosome Location
Chromosome: 1; NC_000001.10 (23345937..23410184). Location: 1p36.12
OMIM
609132
3D Structure
ModBase 3D Structure for O60341
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 819-852 in the C-terminal region of human LSD1, UniProt Accession #O60341. Species sequence homology: Mouse
Conjugate
AP
Note
Preservative Free

Product Categories/Family for anti-LSD1 antibody

Antibodies; Enzymes; Deacetylase
Applications Tested/Suitable for anti-LSD1 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA)
Application Notes for anti-LSD1 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-LSD1 antibody

Western Blot analysis in 293 cell lysates (2ug/lane) usingMBS646290. Lane 1: Nontransfected Lane 2: Transiently transfected with the AOF2 gene.
Rabbit Anti-LSD1 Polyclonal Antibody – Cat# MBS6317450

Western Blot (WB) of anti-LSD1 antibody

Western Blot of nuclear extracts of control and PhIP-treated HMEC. Proteins were transferred onto polyvinylidene difluoride and blotted withMBS646290. Nuclear LSD1 protein levels increased in carcinogen-treated HMEC compared with control HMEC.
Rabbit Anti-LSD1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS6317450

Immunohistochemistry (IHC) of anti-LSD1 antibody

Immunohistochemistry analysis of formalin-fixed and paraffin-embedded human cancer tissue using MBS646290 followed by peroxidase-conjugation of the secondary antibody and DAB staining. This data demonstrates the use of MBS646290 for immunohistochemistry
Rabbit Anti-LSD1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6317450

Testing Data of anti-LSD1 antibody

Rabbit Anti-LSD1 Polyclonal Antibody, Testing Data – Cat# MBS6317450

Product References and Citations for anti-LSD1 antibody

1. Forneris, F., et al. FEBS Lett. 579 (10), 2203-2207 (2005). 2. Shi, Y., et al. Cell 119 (7), 941-953 (2004). 3. Hakimi, M.A., et al. J. Biol. Chem. 278 (9), 7234-7239 (2003). 4. Hakimi, M.A., et al. PNAS 99 (11), 7420-7425 (2002). 5. Humphrey, G.W., et al. J. Biol. Chem. 276 (9), 6817-6824 (2001). 6. Ota, T., et al., Nat. Genet. 36(1):40-45 (2004).

Other Notes

Small volumes of anti-LSD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LSD1. It may not necessarily be applicable to this product.

NCBI GI #
58761544
NCBI GeneID
23028
NCBI Accession #
NP_001009999.1
UniProt Primary Accession #
O60341
UniProt Secondary Accession #
Q5TH94; Q5TH95; Q86VT7; Q8IXK4; Q8NDP6; Q8TAZ3; Q96AW4; A8MWP9
UniProt Related Accession #
O60341
GenBank Nucleotide #
NM_001009999.2
NCBI Official Full Name
lysine-specific histone demethylase 1A isoform a
NCBI Official Synonym Full Names
lysine (K)-specific demethylase 1A
NCBI Official Symbol
KDM1A
NCBI Official Synonym Symbols
AOF2; KDM1; LSD1; BHC110
UniProt Protein Name
Lysine-specific histone demethylase 1A
UniProt Synonym Protein Names
BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2
Protein Family
Lysine-specific histone demethylase
UniProt Gene Name
KDM1A
UniProt Synonym Gene Names
AOF2; KDM1; KIAA0601; LSD1
UniProt Entry Name
KDM1A_HUMAN
NCBI Protein Information
lysine-specific histone demethylase 1A; lysine (K)-specific demethylase 1; BRAF35-HDAC complex protein BHC110; amine oxidase (flavin containing) domain 2; FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit; flavin-containing amine oxidase domain-con

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-LSD1 antibody

 Products by Pathway  Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 Coregulation Of Androgen Receptor Activity Pathway antibodies  Coregulation Of Androgen Receptor Activity Pathway Diagram
 Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies  Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Notch Signaling Pathway antibodies  Notch Signaling Pathway Diagram
 Notch-mediated HES/HEY Network Pathway antibodies  Notch-mediated HES/HEY Network Pathway Diagram

Diseases associated with anti-LSD1 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >54 publications with LSD1 and Neoplasms
 Breast Neoplasms Antibodies  >14 publications with LSD1 and Breast Neoplasms
 Colorectal Neoplasms Antibodies  >7 publications with LSD1 and Colorectal Neoplasms
 Intestinal Neoplasms Antibodies  >5 publications with LSD1 and Intestinal Neoplasms
 Lymphoma Antibodies  >5 publications with LSD1 and Lymphoma
 Disease Models, Animal Antibodies  >4 publications with LSD1 and Disease Models, Animal
 Neoplasm Metastasis Antibodies  >4 publications with LSD1 and Neoplasm Metastasis
 Neoplasm Invasiveness Antibodies  >4 publications with LSD1 and Neoplasm Invasiveness
 Liver Diseases Antibodies  >3 publications with LSD1 and Liver Diseases
 Inflammation Antibodies  >3 publications with LSD1 and Inflammation

Organs/Tissues associated with anti-LSD1 antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >17 publications with LSD1 and Nerve
 Prostate Antibodies  >11 publications with LSD1 and Prostate
 Brain Antibodies  >9 publications with LSD1 and Brain
 Blood Antibodies  >8 publications with LSD1 and Blood
 Lung Antibodies  >6 publications with LSD1 and Lung
 Heart Antibodies  >4 publications with LSD1 and Heart
 Embryonic Tissue Antibodies  >4 publications with LSD1 and Embryonic Tissue
 Muscle Antibodies  >4 publications with LSD1 and Muscle
 Bone Antibodies  >4 publications with LSD1 and Bone
 Liver Antibodies  >3 publications with LSD1 and Liver
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