Rabbit Anti-LZTFL1 Polyclonal Antibody – Cat# MBS6317840

LZTFL1 Antibody – Rabbit Polyclonal

Name: LZTFL1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6317840
Price: 1025 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6317840

LZTFL1 (Leucine zipper transcription factor-like 1) contains a leucine zipper pattern and coiled-coil domains. More details

$1025 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LZTFL1, Polyclonal Antibody

Full Product Name

LZTFL1, NT (LZTFL1, Leucine zipper transcription factor-like protein 1) (MaxLight 405)

Product Gene Name

anti-LZTFL1 antibody

Product Synonym Names

LZTFL1; Leucine zipper transcription factor-like protein 1

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

29,332 Da

OMIM

606568

3D Structure

ModBase 3D Structure for Q9NQ48

Immunogen

LZTFL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-30 amino acids from the N-terminal region of human LZTFL1.

Conjugate

MaxLight405

Note

Preservative Free

Product Categories/Family for anti-LZTFL1 antibody

Antibodies; Transcription Factors

Applications Tested/Suitable for anti-LZTFL1 antibody

Western Blot (WB), FLISA

Application Notes for anti-LZTFL1 antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-LZTFL1 antibody

Wei, Q., et al. Cancer Res. 70(7):2942-2950(2010). Davila, S., et al. Genes Immun. 11(3):232-238(2010). Kiss, H., et al. Genomics 73(1):10-19(2001).

Other Notes

Small volumes of anti-LZTFL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LZTFL1 purchase

MBS6317840 is an antibody targeting LZTFL1. Also known as LZTFL1, NT (LZTFL1, Leucine zipper transcription factor-like protein 1) (MaxLight 405). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LZTFL1. It may not necessarily be applicable to this product.

NCBI GI #

56676319

NCBI GeneID

54585

NCBI Accession #

NP_065080.1

UniProt Primary Accession #

Q9NQ48

UniProt Secondary Accession #

Q8TC61; Q9NQ56; B3KSI9; B4E0K7

UniProt Related Accession #

Q9NQ48

GenBank Nucleotide #

NM_020347.2

NCBI Official Full Name

Homo sapiens leucine zipper transcription factor-like 1 (LZTFL1), mRNA

NCBI Official Synonym Full Names

leucine zipper transcription factor-like 1

NCBI Official Symbol

LZTFL1

NCBI Official Synonym Symbols

BBS17

UniProt Protein Name

Leucine zipper transcription factor-like protein 1

Protein Family

Leucine zipper transcription factor-like protein

UniProt Gene Name

LZTFL1

UniProt Entry Name

LZTL1_HUMAN

NCBI Protein Information

leucine zipper transcription factor-like protein 1

NCBI Summary for LZTFL1

This gene encodes a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in this gene cause a form of Bardet-Biedl Syndrome; a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This gene may also function as a tumor suppressor; possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2013]

UniProt Comments for LZTFL1

LZTFL1: Belongs to the LZTFL1 family.

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: cytosol

Molecular Function: identical protein binding; protein binding; protein complex binding

Disease: Bardet-biedl Syndrome 17

Research Articles on LZTFL1

1. LZTFL1 binds beta-catenin in the cytoplasm of the cell and inhibited its nuclear translocation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LZTFL1 antibody

Reference Product	PubMed Publications
BBS2 antibody	>1 publications with LZTFL1 and BBS2
BBS7 antibody	>1 publications with LZTFL1 and BBS7
BBS9 antibody	>1 publications with LZTFL1 and BBS9

Pathways associated with anti-LZTFL1 antibody

Products by Pathway	Pathway Diagram
Assembly Of The Primary Cilium Pathway antibodies	Assembly Of The Primary Cilium Pathway Diagram
BBSome-mediated Cargo-targeting To Cilium Pathway antibodies	BBSome-mediated Cargo-targeting To Cilium Pathway Diagram
Cargo Trafficking To The Periciliary Membrane Pathway antibodies	Cargo Trafficking To The Periciliary Membrane Pathway Diagram
Organelle Biogenesis And Maintenance Pathway antibodies	Organelle Biogenesis And Maintenance Pathway Diagram

Diseases associated with anti-LZTFL1 antibody

Disease Name	Pubmed Publications
Brain Diseases Antibodies	>3 publications with LZTFL1 and Brain Diseases
Nervous System Diseases Antibodies	>3 publications with LZTFL1 and Nervous System Diseases
Pregnancy Complications Antibodies	>1 publications with LZTFL1 and Pregnancy Complications
Hypertension Antibodies	>1 publications with LZTFL1 and Hypertension
Cognition Disorders Antibodies	>1 publications with LZTFL1 and Cognition Disorders

Organs/Tissues associated with anti-LZTFL1 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>3 publications with LZTFL1 and Brain
Stomach Antibodies	>2 publications with LZTFL1 and Stomach
Blood Antibodies	>1 publications with LZTFL1 and Blood
Intestine Antibodies	>1 publications with LZTFL1 and Intestine
Kidney Antibodies	>1 publications with LZTFL1 and Kidney