Rabbit Anti-MAP2 Polyclonal Antibody – Cat# MBS6486456

MAP2 Antibody – Rabbit Polyclonal

Name: MAP2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6486456
Price: 1025 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6486456

MBS6486456 is an antibody targeting MAP2. Also known as MAP2, NT (Microtubule Associated Protein 2, MAP-2) (MaxLight 405). Reactive in Human. Host: Rabbit. More details

$1025 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MAP2, Polyclonal Antibody

Full Product Name

MAP2, NT (Microtubule Associated Protein 2, MAP-2) (MaxLight 405)

Product Gene Name

anti-MAP2 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.

Purity/Purification

Purified by Protein G Affinity Chromatography.

Specificity

Recognizes human MAP2.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

199.61

OMIM

157130

3D Structure

ModBase 3D Structure for P11137

Immunogen

Synthetic peptide selected from the N-terminal region of human MAP2 (KLH).

Conjugate

MaxLight405

Note

Preservative Free

Product Categories/Family for anti-MAP2 antibody

Antibodies; Microtubule-associated Proteins

Applications Tested/Suitable for anti-MAP2 antibody

Immunohistochemistry (IHC), FLISA

Application Notes for anti-MAP2 antibody

IHC: 1:50-1:100
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-MAP2 antibody

1. Lauckner, J., et al., Neurobiol. Aging 24(6):767-776 (2003). 2. Laurine, E., et al., J. Biol. Chem. 278(32):29979-29986 (2003). 3. Liu, Y., et al., Adv Anat Pathol 10(2):101-106 (2003). 4. DeTure, M.A., et al., J. Biol. Chem. 277(38):34755-34759 (2002). 5. Al-Bassam, J., et al., J. Cell Biol. 157(7):1187-1196 (2002).

Other Notes

Small volumes of anti-MAP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MAP2. It may not necessarily be applicable to this product.

NCBI GI #

87578392

NCBI GeneID

4133

NCBI Accession #

NP_114033

UniProt Primary Accession #

P11137

UniProt Related Accession #

P11137

GenBank Nucleotide #

NP_114033.2

NCBI Official Full Name

microtubule-associated protein 2 isoform 2

NCBI Official Synonym Full Names

microtubule associated protein 2

NCBI Official Symbol

MAP2

NCBI Official Synonym Symbols

MAP-2; MAP2A; MAP2B; MAP2C

UniProt Protein Name

Microtubule-associated protein 2

Protein Family

Microtubule-associated protein

UniProt Gene Name

MAP2

UniProt Synonym Gene Names

MAP-2

UniProt Entry Name

MTAP2_HUMAN

NCBI Protein Information

microtubule-associated protein 2

NCBI Summary for MAP2

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010]

UniProt Comments for MAP2

MAP2: a member of the microtubule-associated protein (MAP) family. Its exact function is unknown but MAPs appear to stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. Expressed at high levels in neural tissue and the prostate. Four alternatively spliced transcript variants have been reported.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q34-q35

Cellular Component: microtubule; microtubule associated complex; cell soma; cytoplasm; nucleolus; dendritic shaft

Molecular Function: calmodulin binding; protein binding; microtubule binding; structural molecule activity

Biological Process: axonogenesis; dendrite morphogenesis; microtubule bundle formation; neurite development; central nervous system neuron development

Research Articles on MAP2

1. These data suggest that early levels of MAP-2 reflect severity of diffuse brain injury and predict 2-week mortality in severe traumatic brain injury patients

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.