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MAT1A Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8108646

The S-adenosylmethionine synthetase type-1 (MAT1A), an essential enzyme in the conversion of methionine to S-adenosylmethionine, plays a key role in homocysteine metabolism. MAT1A encodes the subunit that forms two methionine adenosyltransferase isoenzymes,… More details

$370 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MAT1A, Polyclonal Antibody
Full Product Name
Anti-MAT1A Antibody, Rabbit Polyclonal
Product Gene Name
Product Synonym Names
MAT1A Antibody, Rabbit PAb, Antigen Affinity Purified; methionine adenosyltransferase I, alpha; Anti-MAT Antibody; Anti-MATA1 Antibody; Anti-SAMS Antibody; Anti-SAMS1 Antibody
Clonality
Polyclonal
Isotype
Rabbit IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Purity/Purification
Protein A & Antigen Affinity
Specificity
Human MAT1A
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunogen
E Coli-derived Human MAT1A fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human MAT1A fragment, and purified by antigen affinity chromatography.
Applications Tested/Suitable for anti-MAT1A antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes for anti-MAT1A antibody
IHC-P: 1:100-1:500

Immunohistochemistry (IHC) of anti-MAT1A antibody

Immunochemical staining of human MAT1A in human liver with rabbit polyclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.
Rabbit Anti-MAT1A Polyclonal Antibody – Cat# MBS8108646

Product References and Citations for anti-MAT1A antibody

Murray B, et al. (2019) Methionine adenosyltransferase alpha1 is targeted to the mitochondrial matrix and interacts with cytochrome p450 2e1 to lower its expression. Hepatology 70 (6): 2018-2034.
Maldonado LY, et al. (2018) Methionine adenosyltransferases in cancers: Mechanisms of dysregulation and implications for therapy. Exp Biol Med (Maywood) 243 (2): 107-117.Huang T, et al. (2012) Mat1a variants modulate the effect of dietary fatty acids on plasma homocysteine concentrations. Nutr Metab Cardiovasc Dis 22 (4): 362-368.
Chien YH, et al. (2015) Mudd's disease (mat i/iii deficiency): A survey of data for mat1a homozygotes and compound heterozygotes. Orphanet J Rare Dis 10 99.

Other Notes

Small volumes of anti-MAT1A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MAT1A purchase

MBS8108646 is an antibody targeting MAT1A. Also known as Anti-MAT1A Antibody, Rabbit Polyclonal. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MAT1A. It may not necessarily be applicable to this product.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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