Rabbit Anti-MAZ Polyclonal Antibody – Cat# MBS9216103

All lanes : Anti-MAZ Antibody (Center) at 1:1000 dilution
Lane 1: A549 whole cell lysate
Lane 2: CCRF-CEM whole cell lysate
Lane 3: Hela whole cell lysate
Lane 4: HT-1080 whole cell lysate
Lane 5: THP-1 whole cell lysate

Lysates/proteins at 20 ug per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 49 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.

MAZ Antibody – Rabbit Polyclonal

Name: MAZ Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS9216103
Price: 240 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9216103

May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter… More details

$240 / 0.05 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MAZ, Polyclonal Antibody

Full Product Name

MAZ Antibody (Center)

Product Gene Name

anti-MAZ antibody

Product Synonym Names

Purified Rabbit Polyclonal Antibody (Pab); Myc-associated zinc finger protein; MAZI; Pur-1; Purine-binding transcription factor; Serum amyloid A-activating factor-1; SAF-1; Transcription factor Zif87; ZF87; Zinc finger protein 801; MAZ; ZNF801

Clonality

Polyclonal

Isotype

Host

Rabbit

Species Reactivity

Human

Form/Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Specificity

This MAZ antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 295-327 amino acids from the Central region of human MAZ.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Antibody/Peptide Pairs

MAZ peptide (MBS9230395) is used for blocking the activity of MAZ antibody (MBS9216103)

Molecular Weight

48608

OMIM

600999

3D Structure

ModBase 3D Structure for P56270

Antigen Source

Human

Applications Tested/Suitable for anti-MAZ antibody

Western Blot (WB)

Application Notes for anti-MAZ antibody

WB ~~ 1:1000

Product References and Citations for anti-MAZ antibody

Bossone S.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:7452-7456(1992). Pyrc J.J.,et al.Biochemistry 31:4102-4110(1992). Tsutsui H.,et al.Biochem. Biophys. Res. Commun. 226:801-809(1996). Parks C.L.,et al.J. Biol. Chem. 271:4417-4430(1996). Song J.,et al.J. Biol. Chem. 273:20603-20614(1998).

Other Notes

Small volumes of anti-MAZ antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MAZ purchase

MBS9216103 is an antibody targeting MAZ. Also known as MAZ Antibody (Center). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MAZ. It may not necessarily be applicable to this product.

NCBI GI #

110347459

NCBI GeneID

4150

NCBI Accession #

NP_001036004.1

UniProt Primary Accession #

P56270

UniProt Secondary Accession #

Q15703; Q8NFN7; Q99443; A8QJL9; C6G496; G5E927; H3BQD6

UniProt Related Accession #

P56270

GenBank Nucleotide #

NM_001042539.2

NCBI Official Full Name

myc-associated zinc finger protein isoform 2

NCBI Official Synonym Full Names

MYC-associated zinc finger protein (purine-binding transcription factor)

NCBI Official Symbol

MAZ

NCBI Official Synonym Symbols

PUR1; ZF87; Pur-1; SAF-1; SAF-2; SAF-3; Zif87; ZNF801

UniProt Protein Name

Myc-associated zinc finger protein

UniProt Synonym Protein Names

Pur-1; Purine-binding transcription factor; Serum amyloid A-activating factor-1; SAF-1; Transcription factor Zif87; ZF87; Zinc finger protein 801

Protein Family

Myc-associated zinc finger protein

UniProt Gene Name

MAZ

UniProt Synonym Gene Names

ZNF801; MAZI; SAF-1

UniProt Entry Name

MAZ_HUMAN

NCBI Protein Information

myc-associated zinc finger protein

NCBI Summary for MAZ

MAZ: a myc-associated zinc finger protein. An inflammation-responsive transcription factor with dual roles in transcription initiation and termination. Binds to two sites within the c-myc promoter. Also binds to multiple G/C-rich sites within the promoter of the SP1 family of transcription factors. Expressed in heart, brain, placenta, lung, liver, skeletal muscle and pancreas.

Protein type: C2H2-type zinc finger protein; RNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: protein binding; metal ion binding; chromatin binding

Biological Process: regulation of transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; termination of RNA polymerase II transcription

UniProt Comments for MAZ

MAZ: a myc-associated zinc finger protein. An inflammation-responsive transcription factor with dual roles in transcription initiation and termination. Binds to two sites within the c-myc promoter. Also binds to multiple G/C-rich sites within the promoter of the SP1 family of transcription factors. Expressed in heart, brain, placenta, lung, liver, skeletal muscle and pancreas.

Protein type: C2H2-type zinc finger protein; Transcription factor; RNA-binding

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: nucleus

Molecular Function: chromatin binding; metal ion binding; protein binding

Biological Process: regulation of transcription from RNA polymerase II promoter; termination of RNA polymerase II transcription; transcription initiation from RNA polymerase II promoter

Research Articles on MAZ

1. Studies show a feed-forward regulatory pathway in breast cancer cells where SAF-1 acts as a transcriptional inducer of Ras which in turn increases DNA-binding and transcriptional activities of SAF-1 which in turn, increases transcription of Ras.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MAZ antibody

Reference Product	PubMed Publications
KRAS antibody	>5 publications with MAZ and KRAS
DCC antibody	>2 publications with MAZ and DCC
HRAS antibody	>2 publications with MAZ and HRAS
VEGFA antibody	>1 publications with MAZ and VEGFA
MMP9 antibody	>1 publications with MAZ and MMP9

Pathways associated with anti-MAZ antibody

Products by Pathway	Pathway Diagram
SIDS Susceptibility Pathways antibodies	SIDS Susceptibility Pathways Diagram

Diseases associated with anti-MAZ antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>10 publications with MAZ and Inflammation
Necrosis Antibodies	>8 publications with MAZ and Necrosis
Breast Neoplasms Antibodies	>7 publications with MAZ and Breast Neoplasms
Disease Models, Animal Antibodies	>6 publications with MAZ and Disease Models, Animal
Adenocarcinoma Antibodies	>5 publications with MAZ and Adenocarcinoma
Body Weight Changes Antibodies	>5 publications with MAZ and Body Weight Changes
Prostatic Diseases Antibodies	>3 publications with MAZ and Prostatic Diseases
Neoplasms, Experimental Antibodies	>3 publications with MAZ and Neoplasms, Experimental
Prostatic Neoplasms Antibodies	>3 publications with MAZ and Prostatic Neoplasms
Neoplasm Metastasis Antibodies	>3 publications with MAZ and Neoplasm Metastasis

Organs/Tissues associated with anti-MAZ antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>37 publications with MAZ and Blood
Brain Antibodies	>28 publications with MAZ and Brain
Bone Antibodies	>18 publications with MAZ and Bone
Vascular Antibodies	>14 publications with MAZ and Vascular
Muscle Antibodies	>12 publications with MAZ and Muscle
Heart Antibodies	>11 publications with MAZ and Heart
Skin Antibodies	>10 publications with MAZ and Skin
Liver Antibodies	>10 publications with MAZ and Liver
Nerve Antibodies	>9 publications with MAZ and Nerve
Bone Marrow Antibodies	>9 publications with MAZ and Bone Marrow