• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

MGAT5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6320644

This gene encodes mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, a glycosyltransferase involved in the synthesis of protein-bound and lipid-bound oligosaccharides. Alterations of the oligosaccharides on cell surface… More details

$1025 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MGAT5, Polyclonal Antibody
Full Product Name
MGAT5, CT (MGAT5, GGNT5, Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase, GlcNAc-T V, Mannoside acetylglucosaminyltransferase 5, N-acetylglucosaminyl-transferase V) (MaxLigh
Product Gene Name
anti-MGAT5 antibody
Product Synonym Names
MGAT5; GGNT5; Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A; Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase; GlcNAc-T V; Mannoside acetylglucosaminyltransferase 5; N-acetylglucosaminyl-transferase V
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.
Purity/Purification
Purified by Protein A and Peptide Affinity Chromatography.
Specificity
Recognizes human MGAT5.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
84,543 Da
OMIM
601774
3D Structure
ModBase 3D Structure for Q09328
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 652-680 in the C-terminal region of human MGAT5, UniProt Accession #Q09328.
Conjugate
MaxLight750
Note
Preservative Free

Product Categories/Family for anti-MGAT5 antibody

Antibodies; Enzymes; Glycosyltransferase
Applications Tested/Suitable for anti-MGAT5 antibody
Western Blot (WB), Flow Cytometry (FC/FACS), FLISA
Application Notes for anti-MGAT5 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-MGAT5 antibody

Western Blot analysis in NCI-H460 cell line lysates (35ug/lane) usingMBS6006194. This demonstrates that MBS6006194 detected the MGAT5 protein (arrow).
Rabbit Anti-MGAT5 Polyclonal Antibody – Cat# MBS6320644

Flow Cytometry (FC/FACS) of anti-MGAT5 antibody

Flow Cytometric analysis of NCI-H460 cells using MBS6006194 (right histogram) compared to a negative control cell (left histogram). FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-MGAT5 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS6320644

Product References and Citations for anti-MGAT5 antibody

1. Dick, D.M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (6), 1179-1188 (2010). 2. Brynedal, B., et al. J. Neuroimmunol. 220 (1-2), 120-124 (2010). 3. Benson, V., et al. Int. Immunol. 22(3):167-177 (2010). 4. Wang, C., et al. J. Cell. Biochem. 109(1):113-123 (2010). 5. Ding, H., et al. Stroke 41(1):177-180 (2010).

Other Notes

Small volumes of anti-MGAT5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MGAT5 purchase

MBS6320644 is an antibody targeting MGAT5. Also known as MGAT5, CT (MGAT5, GGNT5, Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase, GlcNAc-T V, Mannoside acetylglucosaminyltransferase 5, N-acetylglucosaminyl-transferase V) (MaxLigh. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MGAT5. It may not necessarily be applicable to this product.

NCBI GI #
4505167
NCBI GeneID
4249
NCBI Accession #
NP_002401.1
UniProt Primary Accession #
Q09328
UniProt Secondary Accession #
D3DP70
UniProt Related Accession #
Q09328
GenBank Nucleotide #
NM_002410.4
NCBI Official Full Name
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A
NCBI Official Synonym Full Names
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
NCBI Official Symbol
MGAT5
NCBI Official Synonym Symbols
GNT-V; GNT-VA
UniProt Protein Name
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A
UniProt Synonym Protein Names
Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase; GlcNAc-T V; GNT-V; Mannoside acetylglucosaminyltransferase 5; N-acetylglucosaminyl-transferase V
Protein Family
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase
UniProt Gene Name
MGAT5
UniProt Synonym Gene Names
GGNT5; GNT-V
NCBI Protein Information
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

NCBI Summary for MGAT5

The protein encoded by this gene belongs to the glycosyltransferase family. It catalyzes the addition of beta-1,6-N-acetylglucosamine to the alpha-linked mannose of biantennary N-linked oligosaccharides present on the newly synthesized glycoproteins. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the activity of this enzyme has been correlated with the progression of invasive malignancies. [provided by RefSeq, Oct 2011]
Show more

UniProt Comments for MGAT5

Catalyzes the addition of N-acetylglucosamine in beta 1-6 linkage to the alpha-linked mannose of biantennary N-linked oligosaccharides. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides.

Research Articles on MGAT5

1. The best homology model is consistent with available experimental data. The three-dimensional model, the structure of the enzyme catalytic site and binding information obtained for the donor and acceptor can be useful in studies of the catalytic mechanism and design of inhibitors of GnT-V.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MGAT5 antibody

 Reference Product  PubMed Publications
 MGAT1 antibody  >7 publications with MGAT5 and MGAT1
 MGAT3 antibody  >5 publications with MGAT5 and MGAT3
 MGAT4A antibody  >3 publications with MGAT5 and MGAT4A
 MGAT4B antibody  >1 publications with MGAT5 and MGAT4B

Pathways associated with anti-MGAT5 antibody

 Products by Pathway  Pathway Diagram
 Asparagine N-linked Glycosylation Pathway antibodies  Asparagine N-linked Glycosylation Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 N-Glycan Antennae Elongation Pathway antibodies  N-Glycan Antennae Elongation Pathway Diagram
 N-Glycan Biosynthesis Pathway antibodies  N-Glycan Biosynthesis Pathway Diagram
 N-Glycan Biosynthesis Pathway antibodies  N-Glycan Biosynthesis Pathway Diagram
 N-glycan Antennae Elongation In The Medial/trans-Golgi Pathway antibodies  N-glycan Antennae Elongation In The Medial/trans-Golgi Pathway Diagram
 N-glycan Biosynthesis, Complex Type Pathway antibodies  N-glycan Biosynthesis, Complex Type Pathway Diagram
 N-glycan Biosynthesis, Complex Type Pathway antibodies  N-glycan Biosynthesis, Complex Type Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram

Diseases associated with anti-MGAT5 antibody

 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >7 publications with MGAT5 and Disease Models, Animal
 Liver Diseases Antibodies  >5 publications with MGAT5 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >5 publications with MGAT5 and Carcinoma, Hepatocellular
 Inflammation Antibodies  >5 publications with MGAT5 and Inflammation
 Liver Neoplasms Antibodies  >4 publications with MGAT5 and Liver Neoplasms
 Liver Neoplasms, Experimental Antibodies  >2 publications with MGAT5 and Liver Neoplasms, Experimental
 Weight Loss Antibodies  >2 publications with MGAT5 and Weight Loss
 Prostatic Diseases Antibodies  >2 publications with MGAT5 and Prostatic Diseases
 Congenital Abnormalities Antibodies  >1 publications with MGAT5 and Congenital Abnormalities
 Kidney Diseases Antibodies  >1 publications with MGAT5 and Kidney Diseases

Organs/Tissues associated with anti-MGAT5 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >14 publications with MGAT5 and Blood
 Nerve Antibodies  >11 publications with MGAT5 and Nerve
 Liver Antibodies  >9 publications with MGAT5 and Liver
 Lung Antibodies  >4 publications with MGAT5 and Lung
 Kidney Antibodies  >4 publications with MGAT5 and Kidney
 Brain Antibodies  >4 publications with MGAT5 and Brain
 Embryonic Tissue Antibodies  >2 publications with MGAT5 and Embryonic Tissue
 Skin Antibodies  >2 publications with MGAT5 and Skin
 Testis Antibodies  >2 publications with MGAT5 and Testis
 Bone Antibodies  >2 publications with MGAT5 and Bone
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000