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MGLL Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9406037

This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and… More details

$320 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MGLL, Polyclonal Antibody
Full Product Name
MGLL antibody
Product Gene Name
anti-MGLL antibody
Product Synonym Names
MGL; HUK5; MAGL; HU-K5
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Antibodies were purified by affinity purification using immunogen.
Concentration
1.0 mg/ml (lot specific)
Specificity
The antibody detects endogenous level of total MGLL antibody.
Preparation and Storage
Store at -20 degree C
Molecular Weight
31,149 Da
OMIM
609699
3D Structure
ModBase 3D Structure for Q99685
Immunogen Type
Recombinant Protein
Immunogen Description
Recombinant protein of human MGLL.
Target Name
MGLL

Product Categories/Family for anti-MGLL antibody

Total protein Ab
Applications Tested/Suitable for anti-MGLL antibody
Western Blot (WB)
Application Notes for anti-MGLL antibody
Western blotting: 1:500 - 1:2000

Western Blot (WB) of anti-MGLL antibody

Western blot analysis of extracts of various cell lines, using MGLL antibody.
Rabbit Anti-MGLL Polyclonal Antibody – Cat# MBS9406037

Other Notes

Small volumes of anti-MGLL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MGLL purchase

MBS9406037 is an antibody targeting MGLL. Also known as MGLL antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MGLL. It may not necessarily be applicable to this product.

NCBI GI #
51242953
NCBI GeneID
11343
NCBI Accession #
NP_001003794.1
UniProt Primary Accession #
Q99685
UniProt Secondary Accession #
Q6IBG9; Q96AA5; B3KRC2; B7Z9D1
UniProt Related Accession #
Q99685
GenBank Nucleotide #
NM_001003794.2
NCBI Official Full Name
monoglyceride lipase isoform 2
NCBI Official Synonym Full Names
monoglyceride lipase
NCBI Official Symbol
MGLL
NCBI Official Synonym Symbols
MGL; HUK5; MAGL; HU-K5
UniProt Protein Name
Monoglyceride lipase
UniProt Synonym Protein Names
HU-K5
Protein Family
Monoglyceride lipase
UniProt Gene Name
MGLL
UniProt Synonym Gene Names
MAGL
UniProt Entry Name
MGLL_HUMAN
NCBI Protein Information
monoglyceride lipase

UniProt Comments for MGLL

MGLL: Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain. Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth. Belongs to the AB hydrolase superfamily. Monoacylglycerol lipase family.

Protein type: EC 3.1.1.23; Lipid Metabolism - glycerolipid; Phospholipase

Chromosomal Location of Human Ortholog: 3q21.3

Cellular Component: nucleoplasm; endoplasmic reticulum membrane; extrinsic to membrane; plasma membrane; synapse; cytosol

Molecular Function: protein homodimerization activity; acylglycerol lipase activity; lipid binding; lysophospholipase activity

Biological Process: platelet activation; glycerophospholipid biosynthetic process; regulation of signal transduction; regulation of axon extension; phospholipid metabolic process; regulation of inflammatory response; triacylglycerol catabolic process; arachidonic acid metabolic process; lipid metabolic process; regulation of sensory perception of pain; inflammatory response; blood coagulation; fatty acid biosynthetic process; acylglycerol catabolic process
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Research Articles on MGLL

1. Molecular dynamics and nudged elastic band simulations were used to explore the conformational transition pathway of the helix alpha4 of human monoacylglycerol lipase.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MGLL antibody

 Reference Product  PubMed Publications
 PNPLA2 antibody  >3 publications with MGLL and PNPLA2
 LIPE antibody  >3 publications with MGLL and LIPE
 LPL antibody  >1 publications with MGLL and LPL
 DAGLA antibody  >1 publications with MGLL and DAGLA

Pathways associated with anti-MGLL antibody

 Products by Pathway  Pathway Diagram
 Acyl Chain Remodeling Of DAG And TAG Pathway antibodies  Acyl Chain Remodeling Of DAG And TAG Pathway Diagram
 Acylglycerol Degradation Pathway antibodies  Acylglycerol Degradation Pathway Diagram
 Acylglycerol Degradation Pathway antibodies  Acylglycerol Degradation Pathway Diagram
 Arachidonate Production From DAG Pathway antibodies  Arachidonate Production From DAG Pathway Diagram
 Effects Of PIP2 Hydrolysis Pathway antibodies  Effects Of PIP2 Hydrolysis Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram

Diseases associated with anti-MGLL antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >6 publications with MGLL and Inflammation
 Disease Models, Animal Antibodies  >3 publications with MGLL and Disease Models, Animal
 Fatty Liver Antibodies  >3 publications with MGLL and Fatty Liver
 Death Antibodies  >3 publications with MGLL and Death
 Breast Neoplasms Antibodies  >2 publications with MGLL and Breast Neoplasms
 Liver Diseases Antibodies  >2 publications with MGLL and Liver Diseases
 Cardiovascular Diseases Antibodies  >1 publications with MGLL and Cardiovascular Diseases
 Weight Gain Antibodies  >1 publications with MGLL and Weight Gain
 Weight Loss Antibodies  >1 publications with MGLL and Weight Loss
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with MGLL and Prenatal Exposure Delayed Effects

Organs/Tissues associated with anti-MGLL antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >6 publications with MGLL and Blood
 Adipose Tissue Antibodies  >5 publications with MGLL and Adipose Tissue
 Liver Antibodies  >4 publications with MGLL and Liver
 Intestine Antibodies  >4 publications with MGLL and Intestine
 Connective Tissue Antibodies  >3 publications with MGLL and Connective Tissue
 Muscle Antibodies  >3 publications with MGLL and Muscle
 Brain Antibodies  >3 publications with MGLL and Brain
 Placenta Antibodies  >1 publications with MGLL and Placenta
 Skin Antibodies  >1 publications with MGLL and Skin
 Pancreas Antibodies  >1 publications with MGLL and Pancreas
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