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Mimecan (OGN) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1492157

MBS1492157 is an antibody targeting OGN. Also known as Rabbit anti-human Mimecan polyclonal Antibody, Biotin conjugated. Reactive in Human. Host: Rabbit. Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2. More details

$230 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Mimecan (OGN), Polyclonal Antibody
Full Product Name
Rabbit anti-human Mimecan polyclonal Antibody, Biotin conjugated
Product Gene Name
anti-OGN antibody
Product Synonym Names
Osteoglycin; Osteoinductive factor; OIF; SLRR3A; OGN
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: Mimecan (MBS7003666)
Biotin Conjugated Antibody: Mimecan (MBS1492157)
Molecular Weight
33,922 Da
OMIM
602383
3D Structure
ModBase 3D Structure for P20774
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Biotin
Immunogen
Recombinant human Mimecan protein(21-298AA)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-47279 / sc-47278 / sc-47277 / sc-67169
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-OGN antibody
ELISA (EIA)

Other Notes

Small volumes of anti-OGN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for OGN. It may not necessarily be applicable to this product.

NCBI GI #
7661704
NCBI GeneID
4969
NCBI Accession #
NP_054776.1
UniProt Primary Accession #
P20774
UniProt Secondary Accession #
Q6FIB0; Q9UF90; Q9UNK5
UniProt Related Accession #
P20774
GenBank Nucleotide #
NM_014057.4
NCBI Official Full Name
mimecan isoform 2
NCBI Official Synonym Full Names
osteoglycin
NCBI Official Symbol
OGN
NCBI Official Synonym Symbols
OG; OIF; SLRR3A
UniProt Protein Name
Mimecan
UniProt Synonym Protein Names
Osteoglycin; Osteoinductive factor; OIF
Protein Family
Mimecan
UniProt Gene Name
OGN
UniProt Synonym Gene Names
OIF; SLRR3A; OIF
UniProt Entry Name
MIME_HUMAN
NCBI Protein Information
mimecan

NCBI Summary for OGN

This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded protein induces ectopic bone formation in conjunction with transforming growth factor beta and may regulate osteoblast differentiation. High expression of the encoded protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
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UniProt Comments for OGN

OGN: Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9q22

Cellular Component: extracellular matrix; extracellular region; extracellular space; Golgi lumen; lysosomal lumen; proteinaceous extracellular matrix

Molecular Function: growth factor activity; heparin binding; protein binding; Roundabout binding

Biological Process: axon extension involved in axon guidance; axonogenesis; carbohydrate metabolic process; glycosaminoglycan metabolic process; keratan sulfate biosynthetic process; keratan sulfate catabolic process; keratan sulfate metabolic process; negative regulation of smooth muscle cell proliferation; regulation of axonogenesis
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Research Articles on OGN

1. OGN might play a role in the development of Ovarian Cancer, and may be a therapeutic target in OC.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-OGN antibody

 Reference Product  PubMed Publications
 OMD antibody  >5 publications with OGN and OMD
 PRELP antibody  >4 publications with OGN and PRELP
 KERA antibody  >4 publications with OGN and KERA
 LUM antibody  >2 publications with OGN and LUM
 FMOD antibody  >1 publications with OGN and FMOD
 CHST6 antibody  >1 publications with OGN and CHST6

Pathways associated with anti-OGN antibody

 Products by Pathway  Pathway Diagram
 Defective B4GALT1 Causes B4GALT1-CDG (CDG-2d) Pathway antibodies  Defective B4GALT1 Causes B4GALT1-CDG (CDG-2d) Pathway Diagram
 Defective CHST6 Causes MCDC1 Pathway antibodies  Defective CHST6 Causes MCDC1 Pathway Diagram
 Defective ST3GAL3 Causes MCT12 And EIEE15 Pathway antibodies  Defective ST3GAL3 Causes MCT12 And EIEE15 Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Diseases Associated With Glycosaminoglycan Metabolism Pathway antibodies  Diseases Associated With Glycosaminoglycan Metabolism Pathway Diagram
 Diseases Of Glycosylation Pathway antibodies  Diseases Of Glycosylation Pathway Diagram
 Glycosaminoglycan Metabolism Pathway antibodies  Glycosaminoglycan Metabolism Pathway Diagram
 Keratan Sulfate Biosynthesis Pathway antibodies  Keratan Sulfate Biosynthesis Pathway Diagram
 Keratan Sulfate Degradation Pathway antibodies  Keratan Sulfate Degradation Pathway Diagram
 Keratan Sulfate/keratin Metabolism Pathway antibodies  Keratan Sulfate/keratin Metabolism Pathway Diagram

Diseases associated with anti-OGN antibody

 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >6 publications with OGN and Brain Diseases
 Hypertrophy Antibodies  >4 publications with OGN and Hypertrophy
 Hypertension Antibodies  >4 publications with OGN and Hypertension
 Disease Models, Animal Antibodies  >4 publications with OGN and Disease Models, Animal
 Fibrosis Antibodies  >3 publications with OGN and Fibrosis
 Inflammation Antibodies  >3 publications with OGN and Inflammation
 Liver Diseases Antibodies  >2 publications with OGN and Liver Diseases
 Atherosclerosis Antibodies  >2 publications with OGN and Atherosclerosis
 Liver Neoplasms Antibodies  >2 publications with OGN and Liver Neoplasms
 Neoplasm Metastasis Antibodies  >2 publications with OGN and Neoplasm Metastasis

Organs/Tissues associated with anti-OGN antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >36 publications with OGN and Bone
 Connective Tissue Antibodies  >20 publications with OGN and Connective Tissue
 Muscle Antibodies  >13 publications with OGN and Muscle
 Brain Antibodies  >13 publications with OGN and Brain
 Heart Antibodies  >8 publications with OGN and Heart
 Vascular Antibodies  >6 publications with OGN and Vascular
 Embryonic Tissue Antibodies  >5 publications with OGN and Embryonic Tissue
 Nerve Antibodies  >5 publications with OGN and Nerve
 Pituitary Gland Antibodies  >4 publications with OGN and Pituitary Gland
 Liver Antibodies  >4 publications with OGN and Liver
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