Rabbit Anti-MLNR Polyclonal Antibody – Cat# MBS6321194

MLNR Antibody – Rabbit Polyclonal

Name: MLNR Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6321194
Price: 1025 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6321194

MBS6321194 is an antibody targeting MLNR. Also known as MLNR, CT (MLNR, GPR38, MTLR, MTLR1, Motilin receptor, G-protein coupled receptor 38) (MaxLight 750). Reactive in Human. Host: Rabbit. More details

$1025 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MLNR, Polyclonal Antibody

Full Product Name

MLNR, CT (MLNR, GPR38, MTLR, MTLR1, Motilin receptor, G-protein coupled receptor 38) (MaxLight 750)

Product Gene Name

anti-MLNR antibody

Product Synonym Names

MLNR; GPR38; MTLR; MTLR1; Motilin receptor; G-protein coupled receptor 38

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Specificity

Recognizes human MLNR.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

45,344 Da

Chromosome Location

Chromosome: 13; NC_000013.10 (49794474..49796513). Location: 13q14-q21

OMIM

602885

3D Structure

ModBase 3D Structure for O43193

Immunogen

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 357-386 in the C-terminal region of human MLNR, UniProt Accession #O43193.

Conjugate

MaxLight750

Note

Preservative Free

Product Categories/Family for anti-MLNR antibody

Antibodies; G Protein Receptors

Applications Tested/Suitable for anti-MLNR antibody

Immunohistochemistry (IHC) Paraffin, Western Blot (WB), FLISA

Application Notes for anti-MLNR antibody

IHC-P: 1:10-1:50
WB: 1:1000
Applications are based on unconjugated antibody.

Product References and Citations for anti-MLNR antibody

1. Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010). 2. Mitselos, A., et al. Peptides 29(7):1167-1175(2008). 3. Ter Beek, W.P., et al. Inflamm. Bowel Dis. 14(5):612-619(2008). 4. Tokunaga, H., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 294 (2), G460-G466 (2008). 5. Dowal, L., et al. J. Biol. Chem. 281(33):23999-24014(2006).

Other Notes

Small volumes of anti-MLNR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MLNR. It may not necessarily be applicable to this product.

NCBI GI #

4504095

NCBI GeneID

2862

NCBI Accession #

NP_001498.1

UniProt Primary Accession #

O43193

UniProt Related Accession #

O43193

GenBank Nucleotide #

NM_001507.1

NCBI Official Full Name

motilin receptor

NCBI Official Synonym Full Names

motilin receptor

NCBI Official Symbol

MLNR

NCBI Official Synonym Symbols

GPR38; MTLR1

UniProt Protein Name

Motilin receptor

UniProt Synonym Protein Names

G-protein coupled receptor 38

Protein Family

Motilin receptor

UniProt Gene Name

MLNR

UniProt Synonym Gene Names

GPR38; MTLR; MTLR1

UniProt Entry Name

MTLR_HUMAN

NCBI Protein Information

motilin receptor; G protein-coupled receptor 38

NCBI Summary for MLNR

Motilin is a 22 amino acid peptide hormone expressed throughout the gastrointestinal (GI) tract. The protein encoded by this gene is a motilin receptor which is a member of the G-protein coupled receptor 1 family. This member is a multi-pass transmembrane protein, and is an important therapeutic target for the treatment of hypomotility disorders. [provided by RefSeq, Aug 2011]

UniProt Comments for MLNR

MLNR: Receptor for motilin. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 13q14-q21

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; growth hormone-releasing hormone receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; digestion

Research Articles on MLNR

1. data support important roles of new regions in the TM domains of the motilin receptor for erythromycin action, suggesting differential mechanisms of actions by peptidyl and non-peptidyl ligands

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MLNR antibody

Reference Product	PubMed Publications
MLN antibody	>2 publications with MLNR and MLN

Pathways associated with anti-MLNR antibody

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram
Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies	Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram