Rabbit Anti-MOAP1 Polyclonal Antibody – Cat# MBS6321564

Western Blot analysis in 293 cell line lysates (35ug/lane) usingMBS6012495. This demonstrates MBS6012495 detected the MOAP1 protein (arrow).

MOAP1 Antibody – Rabbit Polyclonal

Name: MOAP1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6321564
Price: 1025 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6321564

The protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. When overexpressed, this gene has been shown to… More details

$1025 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MOAP1, Polyclonal Antibody

Full Product Name

MOAP1, NT (MOAP1, PNMA4, Modulator of apoptosis 1, Paraneoplastic antigen Ma4) (MaxLight 405)

Product Gene Name

anti-MOAP1 antibody

Product Synonym Names

MOAP1; PNMA4; Modulator of apoptosis 1; Paraneoplastic antigen Ma4

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.

Purity/Purification

Purified by Protein A and Peptide Affinity Chromatography.

Specificity

Recognizes human MOAP1.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

39,513 Da

OMIM

609485

3D Structure

ModBase 3D Structure for Q96BY2

Immunogen

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 37-65 in the N-terminal region of human MOAP1, UniProt Accession #Q96BY2. Species sequence homology: monkey

Conjugate

MaxLight405

Note

Preservative Free

Product Categories/Family for anti-MOAP1 antibody

Antibodies; Apoptosis

Applications Tested/Suitable for anti-MOAP1 antibody

Western Blot (WB), FLISA

Application Notes for anti-MOAP1 antibody

Applications are based on unconjugated antibody.

Product References and Citations for anti-MOAP1 antibody

Lee, S.S., et al. Exp. Cell Res. 315(7):1313-1325(2009)Foley, C.J., et al. Mol. Cell. Biol. 28(14):4520-4535(2008). Fu, N.Y., et al. Proc. Natl. Acad. Sci. U.S.A. 104(24):10051-10056(2007). Lim, J., et al. Cell 125(4):801-814(2006). Vos, M.D., et al. J. Biol. Chem. 281(8):4557-4563(2006).

Other Notes

Small volumes of anti-MOAP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MOAP1 purchase

MBS6321564 is an antibody targeting MOAP1. Also known as MOAP1, NT (MOAP1, PNMA4, Modulator of apoptosis 1, Paraneoplastic antigen Ma4) (MaxLight 405). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MOAP1. It may not necessarily be applicable to this product.

NCBI GI #

19923584

NCBI GeneID

64112

NCBI Accession #

NP_071434.2

UniProt Primary Accession #

Q96BY2

UniProt Secondary Accession #

Q9H833; Q9HAS1; B2RDF6

UniProt Related Accession #

Q96BY2

GenBank Nucleotide #

NM_022151.4

NCBI Official Full Name

modulator of apoptosis 1

NCBI Official Synonym Full Names

modulator of apoptosis 1

NCBI Official Symbol

MOAP1

NCBI Official Synonym Symbols

MAP-1; PNMA4

UniProt Protein Name

Modulator of apoptosis 1

UniProt Synonym Protein Names

Paraneoplastic antigen Ma4

Protein Family

Modulator of apoptosis

UniProt Gene Name

MOAP1

UniProt Synonym Gene Names

PNMA4; MAP-1; MAP1

UniProt Entry Name

MOAP1_HUMAN

NCBI Protein Information

modulator of apoptosis 1; MAP1; paraneoplastic Ma antigen family member 4; paraneoplastic antigen Ma4; paraneoplastic antigen like 4

UniProt Comments for MOAP1

MOAP1: Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. Belongs to the PNMA family.

Chromosomal Location of Human Ortholog: 14q32

Cellular Component: mitochondrial outer membrane; mitochondrion; cytoplasm; cytosol

Molecular Function: protein binding; ubiquitin protein ligase binding

Biological Process: DNA damage response, signal transduction resulting in induction of apoptosis; induction of apoptosis via death domain receptors; protein insertion into mitochondrial membrane during induction of apoptosis; positive regulation of apoptosis

Research Articles on MOAP1

1. PB1-F2 protein of influenza A virus interacts with human MOAP-1 protein.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-MOAP1 antibody

Disease Name	Pubmed Publications
Necrosis Antibodies	>3 publications with MOAP1 and Necrosis
Breast Neoplasms Antibodies	>2 publications with MOAP1 and Breast Neoplasms
Inflammation Antibodies	>2 publications with MOAP1 and Inflammation
Atherosclerosis Antibodies	>1 publications with MOAP1 and Atherosclerosis
Myocardial Infarction Antibodies	>1 publications with MOAP1 and Myocardial Infarction
Hemorrhage Antibodies	>1 publications with MOAP1 and Hemorrhage

Organs/Tissues associated with anti-MOAP1 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>3 publications with MOAP1 and Blood
Vascular Antibodies	>2 publications with MOAP1 and Vascular
Brain Antibodies	>2 publications with MOAP1 and Brain
Nerve Antibodies	>1 publications with MOAP1 and Nerve
Testis Antibodies	>1 publications with MOAP1 and Testis