Rabbit Anti-MOBKL3 Polyclonal Antibody – Cat# MBS6321591

MOBKL3 Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the MOBKL3 antibody detected the MOBKL3 protein (arrow).

MOBKL3 Antibody – Rabbit Polyclonal

Name: MOBKL3 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6321591
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6321591

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MOBKL3, Polyclonal Antibody

Full Product Name

MOBKL3, NT (MOB4, MOB3, MOBKL3, PHOCN, PREI3, MOB-like protein phocein, 2C4D, Class II mMOB1, Mob1 homolog 3, Mps one binder kinase activator-like 3, Preimplantation protein 3) (PE)

Product Gene Name

anti-MOBKL3 antibody

Product Synonym Names

MOB4; MOB3; MOBKL3; PHOCN; PREI3; MOB-like protein phocein; 2C4D; Class II mMOB1; Mob1 homolog 3; Mps one binder kinase activator-like 3; Preimplantation protein 3

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

OMIM

609361

3D Structure

ModBase 3D Structure for Q9Y3A3

Immunogen

MOBKL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MOBKL3.

Conjugate

Note

Preservative Free

Special Handling

Light sensitive

Product Categories/Family for anti-MOBKL3 antibody

Antibodies; Protein Kinases

Applications Tested/Suitable for anti-MOBKL3 antibody

Western Blot (WB), FLISA

Application Notes for anti-MOBKL3 antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-MOBKL3 antibody

Goudreault, M., et al. Mol. Cell Proteomics 8(1):157-171(2009). Hirabayashi, S., et al. Oncogene 27(31):4281-4292(2008). Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007): Stelzl, U., et al. Cell 122(6):957-968(2005). Baillat, G., et al. J. Biol. Chem. 277(21):18961-18966(2002).

Other Notes

Small volumes of anti-MOBKL3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MOBKL3 purchase

MBS6321591 is an antibody targeting MOBKL3. Also known as MOBKL3, NT (MOB4, MOB3, MOBKL3, PHOCN, PREI3, MOB-like protein phocein, 2C4D, Class II mMOB1, Mob1 homolog 3, Mps one binder kinase activator-like 3, Preimplantation protein 3) (PE). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MOBKL3. It may not necessarily be applicable to this product.

NCBI GI #

41349451

NCBI GeneID

25843

NCBI Accession #

NP_955776.1

NCBI Related Accession #

NP_056202.2

UniProt Primary Accession #

Q9Y3A3

UniProt Related Accession #

Q9Y3A3

GenBank Nucleotide #

NP_955776.1

NCBI Official Full Name

MOB-like protein phocein isoform 2

NCBI Official Synonym Full Names

MOB family member 4, phocein

NCBI Official Symbol

MOB4

NCBI Official Synonym Symbols

2C4D; MOB1; MOB3; PHOCN; PREI3; CGI-95; MOBKL3

UniProt Protein Name

MOB-like protein phocein

UniProt Synonym Protein Names

2C4D; Class II mMOB1; Mob1 homolog 3; Mob3; Mps one binder kinase activator-like 3; Preimplantation protein 3

UniProt Gene Name

MOB4

UniProt Synonym Gene Names

MOB3; MOBKL3; PHOCN; PREI3; Mob3

UniProt Entry Name

PHOCN_HUMAN

NCBI Protein Information

MOB-like protein phocein

NCBI Summary for MOBKL3

This gene was identified based on its similarity with the mouse counterpart. Studies of the mouse counterpart suggest that the expression of this gene may be regulated during oocyte maturation and preimplantation following zygotic gene activation. Alternatively spliced transcript variants encoding distinct isoforms have been observed. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HSPE1.[provided by RefSeq, Feb 2011]

UniProt Comments for MOBKL3

PREI3: May play a role in membrane trafficking, specifically in membrane budding reactions. Belongs to the MOB1/phocein family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Activator; Membrane protein, peripheral; Protein kinase, regulatory subunit

Chromosomal Location of Human Ortholog: 2q33.1

Cellular Component: Golgi apparatus; cell soma; perinuclear region of cytoplasm; cytoplasm; dendritic spine; cytosol

Molecular Function: protein binding; metal ion binding; kinase binding

Biological Process: transport

Research Articles on MOBKL3

1. Because of divergent evolution of key interface residues, MST4 and MOB4 could disrupt assembly of the MST1-MOB1 complex through alternative pairing and thereby increased YAP activity. Collectively, these findings identify the MST4-MOB4 complex as a noncanonical regulator of the Hippo-YAP pathway with an oncogenic role in PC

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.