Rabbit Anti-MORF4L2 Polyclonal Antibody – Cat# MBS6321706

MORF4L2 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the MORF4L2 antibody detected the MORF4L2 protein (arrow).

MORF4L2 Antibody – Rabbit Polyclonal

Name: MORF4L2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6321706
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6321706

Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote… More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MORF4L2, Polyclonal Antibody

Full Product Name

MORF4L2, CT (MORF4L2, KIAA0026, MRGX, Mortality factor 4-like protein 2, MORF-related gene X protein, Protein MSL3-2, Transcription factor-like protein MRGX) (Azide free) (HRP)

Product Gene Name

anti-MORF4L2 antibody

Product Synonym Names

MORF4L2; KIAA0026; MRGX; Mortality factor 4-like protein 2; MORF-related gene X protein; Protein MSL3-2; Transcription factor-like protein MRGX

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

OMIM

300409

3D Structure

ModBase 3D Structure for Q15014

Immunogen

MORF4L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-288 amino acids from the C-terminal region of human MORF4L2.

Conjugate

HRP

Note

Preservative Free

Product Categories/Family for anti-MORF4L2 antibody

Antibodies; Transcription Factors

Applications Tested/Suitable for anti-MORF4L2 antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-MORF4L2 antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-MORF4L2 antibody

Pezo, R.C., et al. Cancer Res. 68(13):4977-4982(2008). Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007): Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005). Cai, Y., et al. J. Biol. Chem. 280(14):13665-13670(2005). Tominaga, K., et al. J. Biol. Chem. 278(49):49618-49624(2003).

Other Notes

Small volumes of anti-MORF4L2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MORF4L2 purchase

MBS6321706 is an antibody targeting MORF4L2. Also known as MORF4L2, CT (MORF4L2, KIAA0026, MRGX, Mortality factor 4-like protein 2, MORF-related gene X protein, Protein MSL3-2, Transcription factor-like protein MRGX) (Azide free) (HRP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MORF4L2. It may not necessarily be applicable to this product.

NCBI GI #

215490043

NCBI GeneID

9643

NCBI Accession #

NP_001135901.1

NCBI Related Accession #

NP_001135891.1; NP_001135898.1

UniProt Primary Accession #

Q15014

UniProt Related Accession #

Q15014

GenBank Nucleotide #

NP_001135901.1

NCBI Official Full Name

mortality factor 4-like protein 2

NCBI Official Synonym Full Names

mortality factor 4 like 2

NCBI Official Symbol

MORF4L2

NCBI Official Synonym Symbols

MRGX; MORFL2

UniProt Protein Name

Mortality factor 4-like protein 2

UniProt Synonym Protein Names

MORF-related gene X protein; Protein MSL3-2; Transcription factor-like protein MRGX

Protein Family

Mortality factor 4-like protein

UniProt Gene Name

MORF4L2

UniProt Synonym Gene Names

KIAA0026; MRGX

UniProt Entry Name

MO4L2_HUMAN

NCBI Protein Information

mortality factor 4-like protein 2

UniProt Comments for MORF4L2

MORF4L2: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.

Chromosomal Location of Human Ortholog: Xq22

Cellular Component: nucleoplasm; nucleolus

Molecular Function: protein binding

Biological Process: establishment and/or maintenance of chromatin architecture; transcription, DNA-dependent; regulation of growth; positive regulation of transcription from RNA polymerase II promoter; positive regulation of striated muscle cell differentiation; chromatin modification; DNA repair

Research Articles on MORF4L2

1. Suberoylanilide hydroxamic acid enhanced the expression of malignant genes such as MORF4L2 in lung cancer cells remaining after treatment, creating a more drug-resistant state.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.