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MPRIP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3222976

Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by… More details

$490 / 0.1 mL +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
MPRIP, Polyclonal Antibody
Full Product Name
MPRIP Antibody - N-terminal region
Product Gene Name
Product Synonym Gene Name
MRIP; RIP3; M-RIP; RHOIP3; p116Rip
Immunogen Sequence
Synthetic peptide located within the following region: RTNKQNQKKK RKVEPPTPQE PGPAKVAVTS SSSSSSSSSS IPSAEKVPTT
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity purified
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
MPRIP peptide (MBS3247628) is used for blocking the activity of MPRIP antibody (MBS3222976)
Molecular Weight
110 kDa
OMIM
612935
3D Structure
ModBase 3D Structure for Q6WCQ1
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human MPRIP
Applications Tested/Suitable for anti-MPRIP antibody
Western Blot (WB)

Western Blot (WB) of anti-MPRIP antibody

Host: Rabbit
Target Name: MPRIP
Sample Tissue: Human Jurkat Whole Cell lysates
Antibody Dilution: 1ug/ml
Rabbit Anti-MPRIP Polyclonal Antibody – Cat# MBS3222976

Other Notes

Small volumes of anti-MPRIP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MPRIP purchase

MBS3222976 is an antibody targeting MPRIP. Also known as MPRIP Antibody - N-terminal region. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MPRIP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
myosin phosphatase Rho-interacting protein isoform 1
NCBI Official Synonym Full Names
myosin phosphatase Rho interacting protein
NCBI Official Symbol
MPRIP
NCBI Official Synonym Symbols
MRIP; RIP3; M-RIP; RHOIP3; p116Rip
UniProt Protein Name
Myosin phosphatase Rho-interacting protein
UniProt Synonym Protein Names
Rho-interacting protein 3; RIP3; p116Rip
UniProt Gene Name
MPRIP
UniProt Synonym Gene Names
KIAA0864; MRIP; RHOIP3; M-RIP; RIP3
UniProt Entry Name
MPRIP_HUMAN
NCBI Protein Information
myosin phosphatase Rho-interacting protein

UniProt Comments for MPRIP

RIP3: Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F- actin-binding region leads to disassembly of stress fibers in neuronal cells. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: GAPs, Rac/Rho; GAPs

Chromosomal Location of Human Ortholog: 17p11.2

Cellular Component: focal adhesion; cytoplasm; actin cytoskeleton

Molecular Function: protein binding; actin binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-MPRIP antibody

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