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MRPS23 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9209032

Mammalian mitochondrial ribosomal proteins are encoded bynuclear genes and help in protein synthesis within themitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of asmall 28S subunit and a large 39S subunit. They have an estimated75% protein to… More details

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Product Overview

Online Datasheet in PDF
Product Name
MRPS23, Polyclonal Antibody
Full Product Name
MRPS23 Antibody (Center)
Product Gene Name
Product Synonym Names
28S ribosomal protein S23; mitochondrial; MRP-S23; S23mt; MRPS23
Clonality
Polyclonal
Isotype
Rabbit Ig
Host
Rabbit
Species Reactivity
Human
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Concentration
Vial Concentration: 0.5 (lot specific)
Specificity
This MRPS23 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-76 amino acids from the Central region of human MRPS23.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
MRPS23 peptide (MBS9223381) is used for blocking the activity of MRPS23 antibody (MBS9209032)
Molecular Weight
21771
Immunogen Sequence Positions
50-76
OMIM
611985
3D Structure
ModBase 3D Structure for Q9Y3D9
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Applications Tested/Suitable for anti-MRPS23 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-MRPS23 antibody
WB~~1:1000

Western Blot (WB) of anti-MRPS23 antibody

MRPS23 Antibody (Center) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the MRPS23 Antibody detected the MRPS23 protein (arrow).
Rabbit Anti-MRPS23 Polyclonal Antibody – Cat# MBS9209032

Product References and Citations for anti-MRPS23 antibody

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Zhang, Z., et al. Genomics 81(5):468-480(2003)
Kenmochi, N., et al. Genomics 77 (1-2), 65-70 (2001) :
Cavdar Koc, E., et al. J. Biol. Chem. 276(22):19363-19374(2001)
Koc, E.C., et al. J. Biol. Chem. 275(42):32585-32591(2000)

Other Notes

Small volumes of anti-MRPS23 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MRPS23 purchase

MBS9209032 is an antibody targeting MRPS23. Also known as MRPS23 Antibody (Center). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MRPS23. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
28S ribosomal protein S23, mitochondrial
NCBI Official Synonym Full Names
mitochondrial ribosomal protein S23
NCBI Official Symbol
MRPS23
NCBI Official Synonym Symbols
CGI-138; HSPC329; MRP-S23
UniProt Protein Name
28S ribosomal protein S23, mitochondrial
Protein Family
UniProt Gene Name
MRPS23
UniProt Synonym Gene Names
MRP-S23; S23mt
UniProt Entry Name
RT23_HUMAN
NCBI Protein Information
28S ribosomal protein S23, mitochondrial

NCBI Summary for MRPS23

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 7p. [provided by RefSeq, Jul 2008]
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UniProt Comments for MRPS23

MRPS23: Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.

Protein type: Mitochondrial; Translation; Ribosomal

Chromosomal Location of Human Ortholog: 17q22-q23

Cellular Component: intermediate filament cytoskeleton; nuclear membrane; mitochondrion; mitochondrial inner membrane; ribosome

Molecular Function: structural constituent of ribosome

Biological Process: mitochondrial translation; organelle organization and biogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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