Rabbit Anti-MS4A8B Polyclonal Antibody – Cat# MBS6322450

MS4A8B Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the MS4A8B antibody detected the MS4A8B protein (arrow).

MS4A8B Antibody – Rabbit Polyclonal

Name: MS4A8B Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6322450
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6322450

This gene encodes a member of the membrane-spanning 4A gene family. Members of this protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and… More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MS4A8B, Polyclonal Antibody

Full Product Name

MS4A8B, NT (MS4A8B, 4SPAN4, Membrane-spanning 4-domains subfamily A member 8B, Four-span transmembrane protein 4) (AP)

Product Gene Name

anti-MS4A8B antibody

Product Synonym Names

MS4A8B; 4SPAN4; Membrane-spanning 4-domains subfamily A member 8B; Four-span transmembrane protein 4

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

26,290 Da

Chromosome Location

Chromosome: 11; NC_000011.9 (60467046..60483284). Location: 11q12.2

OMIM

606549

3D Structure

ModBase 3D Structure for Q9BY19

Immunogen

MS4A8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-70 amino acids from the N-terminal region of human MS4A8B.

Conjugate

Note

Preservative Free

Product Categories/Family for anti-MS4A8B antibody

Antibodies; Membrane Proteins

Applications Tested/Suitable for anti-MS4A8B antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-MS4A8B antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-MS4A8B antibody

Lamesch, P., et al. Genomics 89(3):307-315(2007). Liang, Y., et al. Immunogenetics 53(5):357-368(2001). Liang, Y., et al. Genomics 72(2):119-127(2001). Ishibashi, K., et al. Gene 264(1):87-93(2001).

Other Notes

Small volumes of anti-MS4A8B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MS4A8B purchase

MBS6322450 is an antibody targeting MS4A8B. Also known as MS4A8B, NT (MS4A8B, 4SPAN4, Membrane-spanning 4-domains subfamily A member 8B, Four-span transmembrane protein 4) (AP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MS4A8B. It may not necessarily be applicable to this product.

NCBI GI #

13899295

NCBI GeneID

83661

NCBI Accession #

NP_113645.1

UniProt Primary Accession #

Q9BY19

UniProt Secondary Accession #

Q8TCA5

UniProt Related Accession #

Q9BY19

GenBank Nucleotide #

NM_031457.1

NCBI Official Full Name

membrane-spanning 4-domains subfamily A member 8

NCBI Official Synonym Full Names

membrane-spanning 4-domains, subfamily A, member 8

NCBI Official Symbol

MS4A8

NCBI Official Synonym Symbols

MS4A4; 4SPAN4; CD20L5; MS4A8B

UniProt Protein Name

Membrane-spanning 4-domains subfamily A member 8

UniProt Synonym Protein Names

Four-span transmembrane protein 4; Membrane-spanning 4-domains subfamily A member 8B

UniProt Gene Name

MS4A8

UniProt Synonym Gene Names

4SPAN4; MS4A8B

UniProt Entry Name

M4A8_HUMAN

NCBI Protein Information

membrane-spanning 4-domains subfamily A member 8; four-span transmembrane protein 4; membrane-spanning 4-domains, subfamily A, member 8B

UniProt Comments for MS4A8B

Function: May be involved in signal transduction as a component of a multimeric receptor complex.

Subcellular location: Membrane; Multi-pass membrane protein.

Tissue specificity: Expressed by hematopoietic tissues and cells lines.

Sequence similarities: Belongs to the MS4A family.

Research Articles on MS4A8B

1. MS4A8B is a novel differentiation marker of the intestinal epithelium that supports the maintenance of a physiological barrier function in the gut by modulating the transcriptome and by conferring an increased resistance to reactive oxygen species.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-MS4A8B antibody

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>2 publications with MS4A8B and Lung