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STK24 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS624963

The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Mst3 (Stk24), Polyclonal Antibody
Full Product Name
Mst3, CT (Mammalian STE20-like Protein Kinase 3, MST-3, MST3B, Serine/threonine Kinase 24 (Ste20, Yeast Homolog), STE20 Homolog (yeast), STE20-like Kinase MST3, STK3, STK24)
Product Gene Name
anti-Stk24 antibody
Product Synonym Names
Anti -Mst3, CT (Mammalian STE20-like Protein Kinase 3, MST-3, MST3B, Serine/threonine Kinase 24 (Ste20, Yeast Homolog), STE20 Homolog (yeast), STE20-like Kinase MST3, STK3, STK24)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human MST3.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
47,954 Da
Chromosome Location
Chromosome: 14; NC_000080.6 (121286341..121379230, complement). Location: 14 E5; 14 64.95 cM
3D Structure
ModBase 3D Structure for Q99KH8
Immunogen
Synthetic peptide selected from the C-terminal region of human MST3 (KLH).

Product Categories/Family for anti-Stk24 antibody

Antibodies; Abs to Protein Kinases
Applications Tested/Suitable for anti-Stk24 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-Stk24 antibody
Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100

Western Blot (WB) of anti-Stk24 antibody

Western blot analysis of MST3 Antibody (C-term) in HepG2 cell line lysates (35ug/lane). MST3 (arrow) was detected using the purified Pab.
Rabbit Anti-STK24 Polyclonal Antibody – Cat# MBS624963

Immunohistochemistry (IHC) of anti-Stk24 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Rabbit Anti-STK24 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS624963

Other Notes

Small volumes of anti-Stk24 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Stk24 purchase

MBS624963 is an antibody targeting Stk24. Also known as Mst3, CT (Mammalian STE20-like Protein Kinase 3, MST-3, MST3B, Serine/threonine Kinase 24 (Ste20, Yeast Homolog), STE20 Homolog (yeast), STE20-like Kinase MST3, STK3, STK24). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Stk24. It may not necessarily be applicable to this product.

NCBI GI #
37778634
NCBI GeneID
223255
NCBI Accession #
AAO34125.1
UniProt Primary Accession #
Q99KH8
UniProt Related Accession #
Q99KH8
NCBI Official Full Name
mammalian sterile twenty 3 kinase
NCBI Official Synonym Full Names
serine/threonine kinase 24
NCBI Official Symbol
Stk24
NCBI Official Synonym Symbols
Mst3; MST-3; STE20; C76483; 1810013H02Rik
UniProt Protein Name
Serine/threonine-protein kinase 24
UniProt Synonym Protein Names
Mammalian STE20-like protein kinase 3; MST-3; STE20-like kinase MST3Cleaved into the following 2 chains:Serine/threonine-protein kinase 24 35 kDa subunit; Alternative name(s):; Mammalian STE20-like protein kinase 3 N-terminal; MST3/NSerine/threonine-protein kinase 24 12 kDa subunit; Alternative name(s):; Mammalian STE20-like protein kinase 3 C-terminal
Protein Family
Serine/threonine-protein kinase
UniProt Gene Name
Stk24
UniProt Synonym Gene Names
Mst3; Stk3; MST-3; MST3/N; MST3/C
UniProt Entry Name
STK24_MOUSE
NCBI Protein Information
serine/threonine-protein kinase 24; STE20-like kinase MST3; mammalian sterile twenty 3 kinase; mammalian STE20-like protein kinase 3; serine/threonine kinase 24 (STE20 homolog, yeast)

UniProt Comments for Stk24

MST3: a protein kinase of the STE20 family. Activated by caspase-mediated cleavage

Protein type: Protein kinase, STE; EC 2.7.11.1; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); STE group; STE20 family; YSK subfamily

Cellular Component: Golgi membrane; membrane; cytoplasm; nucleolus; nucleus

Molecular Function: transferase activity; protein serine/threonine kinase activity; metal ion binding; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; ATP binding; protein kinase activity; receptor signaling protein serine/threonine kinase activity

Biological Process: regulation of axon regeneration; positive regulation of axon regeneration; response to hydrogen peroxide; apoptosis; protein amino acid autophosphorylation; regulation of cell differentiation; response to stress; phosphorylation; protein amino acid phosphorylation; induction of apoptosis by oxidative stress; negative regulation of cell migration
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Stk24 antibody

 Reference Product  PubMed Publications
 Ccm2 antibody  >3 publications with Stk24 and Ccm2

Pathways associated with anti-Stk24 antibody

 Products by Pathway  Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptotic Execution Phase Pathway antibodies  Apoptotic Execution Phase Pathway Diagram

Diseases associated with anti-Stk24 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >5 publications with Stk24 and Neoplasms
 Nervous System Diseases Antibodies  >4 publications with Stk24 and Nervous System Diseases
 Congenital Abnormalities Antibodies  >2 publications with Stk24 and Congenital Abnormalities
 Cardiovascular Diseases Antibodies  >2 publications with Stk24 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >1 publications with Stk24 and Disease Models, Animal
 Brain Diseases Antibodies  >1 publications with Stk24 and Brain Diseases
 Inflammation Antibodies  >1 publications with Stk24 and Inflammation

Organs/Tissues associated with anti-Stk24 antibody

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >2 publications with Stk24 and Eye
 Dorsal Root Ganglion Antibodies  >1 publications with Stk24 and Dorsal Root Ganglion
 Brain Antibodies  >1 publications with Stk24 and Brain
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