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MYT1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8101447

MYT1, encoding the myelin transcription factor 1, was reported as the first gene involved in OAVS, within the retinoic acid (RA) pathway. MYT1 overexpression downregulated all RA receptors genes (RARA, RARB, RARG), involved in RA-mediated transcription,… More details

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Product Overview

Online Datasheet in PDF
Product Name
MYT1, Polyclonal Antibody
Full Product Name
Anti-MYT1 Antibody, Rabbit Polyclonal
Product Gene Name
Product Synonym Names
MYT1 Antibody, Rabbit PAb, Antigen Affinity Purified; Anti-C20orf36 Antibody; Anti-MTF1 Antibody; Anti-MYTI Antibody; Anti-PLPB1 Antibody; Anti-ZC2HC4A Antibody
Clonality
Polyclonal
Isotype
Rabbit IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid; 0.2um filtered solution in PBS
Purity/Purification
Protein A & Antigen Affinity
Specificity
Human MYT1
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Molecular Weight
125,075 Da
OMIM
600379
3D Structure
ModBase 3D Structure for Q01538
Immunogen
A synthetic peptide corresponding to the center region of the Human MYT1
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human MYT1, and purified by antigen affinity chromatography.
Applications Tested/Suitable for anti-MYT1 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes for anti-MYT1 antibody
IHC-P: 1:500-1:2000

Immunohistochemistry (IHC) of anti-MYT1 antibody

Immunochemical staining of human MYT1 in human brain with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
Rabbit Anti-MYT1 Polyclonal Antibody – Cat# MBS8101447

Immunohistochemistry (IHC) of anti-MYT1 antibody

Immunochemical staining of human MYT1 in human colon carcinoma with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
Rabbit Anti-MYT1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS8101447

Other Notes

Small volumes of anti-MYT1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MYT1 purchase

MBS8101447 is an antibody targeting MYT1. Also known as Anti-MYT1 Antibody, Rabbit Polyclonal. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MYT1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
myelin transcription factor 1
NCBI Official Synonym Full Names
myelin transcription factor 1
NCBI Official Symbol
MYT1
NCBI Official Synonym Symbols
MTF1; MYTI; NZF2; PLPB1; ZC2HC4A; C20orf36
UniProt Protein Name
Myelin transcription factor 1
UniProt Synonym Protein Names
Myelin transcription factor I; MyTI; PLPB1; Proteolipid protein-binding protein
UniProt Gene Name
MYT1
UniProt Synonym Gene Names
KIAA0835; KIAA1050; MTF1; MYTI; PLPB1; MyT1; MyTI
UniProt Entry Name
MYT1_HUMAN
NCBI Protein Information
myelin transcription factor 1; myelin transcription factor I; proteolipid protein binding protein; proteolipid protein-binding protein; neural zinc finger transcription factor 2

NCBI Summary for MYT1

The protein encoded by this gene is a member of a family of neural specific, zinc finger-containing DNA-binding proteins. The protein binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system. [provided by RefSeq, Jul 2008]

UniProt Comments for MYT1

PLPB1: Binds to the promoter regions of proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendrogalia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 20q13.33

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: zinc ion binding; transcription factor activity

Biological Process: nervous system development; regulation of transcription, DNA-dependent; transcription, DNA-dependent; cell differentiation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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