Rabbit Anti-NCAPG Polyclonal Antibody – Cat# MBS6324049

NCAPG Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the NCAPG antibody detected the NCAPG protein (arrow).

NCAPG Antibody – Rabbit Polyclonal

Name: NCAPG Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6324049
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6324049

Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I… More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NCAPG, Polyclonal Antibody

Full Product Name

NCAPG, NT (NCAPG, CAPG, NYMEL3, Condensin complex subunit 3, Chromosome-associated protein G, Condensin subunit CAP-G, Melanoma antigen NY-MEL-3, Non-SMC condensin I complex subunit G, XCAP-G homolog) (Azide free) (HRP)

Product Gene Name

anti-NCAPG antibody

Product Synonym Names

NCAPG; CAPG; NYMEL3; Condensin complex subunit 3; Chromosome-associated protein G; Condensin subunit CAP-G; Melanoma antigen NY-MEL-3; Non-SMC condensin I complex subunit G; XCAP-G homolog

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

114,334 Da

Chromosome Location

Chromosome: 4; NC_000004.11 (17812436..17846488). Location: 4p15.33

OMIM

606280

3D Structure

ModBase 3D Structure for Q9BPX3

Immunogen

NCAPG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-145 amino acids from the N-terminal region of human NCAPG.

Conjugate

HRP

Note

Preservative Free

Product Categories/Family for anti-NCAPG antibody

Antibodies; Cancer Markers

Applications Tested/Suitable for anti-NCAPG antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-NCAPG antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-NCAPG antibody

Okada, Y., et al. Hum. Mol. Genet. 19(11):2303-2312(2010). Zhao, J., et al. BMC Med. Genet. 11, 96 (2010): Murphy, L.A., et al. Biochem. Biophys. Res. Commun. 377(3):1007-1011(2008). Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008). Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007).

Other Notes

Small volumes of anti-NCAPG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NCAPG purchase

MBS6324049 is an antibody targeting NCAPG. Also known as NCAPG, NT (NCAPG, CAPG, NYMEL3, Condensin complex subunit 3, Chromosome-associated protein G, Condensin subunit CAP-G, Melanoma antigen NY-MEL-3, Non-SMC condensin I complex subunit G, XCAP-G homolog) (Azide free) (HRP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NCAPG. It may not necessarily be applicable to this product.

NCBI GI #

21359945

NCBI GeneID

64151

NCBI Accession #

NP_071741.2

UniProt Primary Accession #

Q9BPX3

UniProt Secondary Accession #

Q3MJE0; Q96SV9; Q9BUR3; Q9BVY1; Q9H914; Q9H9Z6; Q9HBI9

UniProt Related Accession #

Q9BPX3

GenBank Nucleotide #

NM_022346.4

NCBI Official Full Name

condensin complex subunit 3

NCBI Official Synonym Full Names

non-SMC condensin I complex, subunit G

NCBI Official Symbol

NCAPG

NCBI Official Synonym Symbols

CAPG; CHCG; NY-MEL-3

UniProt Protein Name

Condensin complex subunit 3

UniProt Synonym Protein Names

Chromosome-associated protein G; Condensin subunit CAP-G; hCAP-G; Melanoma antigen NY-MEL-3; Non-SMC condensin I complex subunit G; XCAP-G homolog

UniProt Gene Name

NCAPG

UniProt Synonym Gene Names

CAPG; NYMEL3; hCAP-G

UniProt Entry Name

CND3_HUMAN

NCBI Protein Information

condensin complex subunit 3; XCAP-G homolog; condensin subunit CAP-G; melanoma antigen NY-MEL-3; chromosome-associated protein G; chromosome condensation protein G

NCBI Summary for NCAPG

This gene encodes a subunit of the condensin complex, which is responsible for the condensation and stabilization of chromosomes during mitosis and meiosis. Phosphorylation of the encoded protein activates the condensin complex. There are pseudogenes for this gene on chromosomes 8 and 15. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

UniProt Comments for NCAPG

NCAPG: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Belongs to the CND3 (condensin subunit 3) family.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 4p15.33

Cellular Component: centrosome; membrane; cytoplasm; condensin complex; nucleus; cytosol; actin cytoskeleton

Molecular Function: protein binding

Biological Process: cell division; mitotic chromosome condensation; mitotic cell cycle

Research Articles on NCAPG

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NCAPG antibody

Reference Product	PubMed Publications
DNMT3B antibody	>1 publications with NCAPG and DNMT3B

Pathways associated with anti-NCAPG antibody

Products by Pathway	Pathway Diagram
Aurora B Signaling Pathway antibodies	Aurora B Signaling Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Cell Cycle, Mitotic Pathway antibodies	Cell Cycle, Mitotic Pathway Diagram
Condensation Of Prometaphase Chromosomes Pathway antibodies	Condensation Of Prometaphase Chromosomes Pathway Diagram
M Phase Pathway antibodies	M Phase Pathway Diagram
Mitotic Prometaphase Pathway antibodies	Mitotic Prometaphase Pathway Diagram

Diseases associated with anti-NCAPG antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>1 publications with NCAPG and Neoplasms

Organs/Tissues associated with anti-NCAPG antibody

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>3 publications with NCAPG and Muscle
Bone Antibodies	>2 publications with NCAPG and Bone
Liver Antibodies	>1 publications with NCAPG and Liver
Connective Tissue Antibodies	>1 publications with NCAPG and Connective Tissue
Blood Antibodies	>1 publications with NCAPG and Blood
Embryonic Tissue Antibodies	>1 publications with NCAPG and Embryonic Tissue