Rabbit Anti-NCKAP1 Polyclonal Antibody – Cat# MBS6006988

NCKAP1 Antibody (Center) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the NCKAP1 antibody detected the NCKAP1 protein (arrow).

NCKAP1 Antibody – Rabbit Polyclonal

Name: NCKAP1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6006988
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6006988

MBS6006988 is an antibody targeting Nckap1. Also known as NCKAP1, ID (NCKAP1, HEM2, KIAA0587, NAP1, Nck-associated protein 1, Membrane-associated protein HEM-2, p125Nap1). Reactive in Human. Host: Rabbit. More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NCKAP1, Polyclonal Antibody

Full Product Name

NCKAP1, ID (NCKAP1, HEM2, KIAA0587, NAP1, Nck-associated protein 1, Membrane-associated protein HEM-2, p125Nap1)

Product Gene Name

anti-Nckap1 antibody

Product Synonym Names

Anti -NCKAP1, ID (NCKAP1, HEM2, KIAA0587, NAP1, Nck-associated protein 1, Membrane-associated protein HEM-2, p125Nap1)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

128,865 Da

Chromosome Location

Chromosome: 3; NC_005102.3 (74284277..74361208, complement). Location: 3q24

3D Structure

ModBase 3D Structure for P55161

Immunogen

NCKAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 640-670 amino acids from the Central region of human NCKAP1.

Product Categories/Family for anti-Nckap1 antibody

Antibodies; Abs to KIAA; orf

Applications Tested/Suitable for anti-Nckap1 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-Nckap1 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-Nckap1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Nckap1. It may not necessarily be applicable to this product.

NCBI GI #

62531004

NCBI GeneID

58823

NCBI Accession #

AAH92610.1

UniProt Primary Accession #

P55161

UniProt Related Accession #

P55161

NCBI Official Full Name

Nckap1 protein, partial

NCBI Official Synonym Full Names

NCK-associated protein 1

NCBI Official Symbol

Nckap1

UniProt Protein Name

Nck-associated protein 1

UniProt Synonym Protein Names

Membrane-associated protein HEM-2; p125Nap1

Protein Family

Nck-associated protein

UniProt Gene Name

Nckap1

UniProt Synonym Gene Names

Hem2; Nap1; NAP 1

UniProt Entry Name

NCKP1_RAT

NCBI Protein Information

nck-associated protein 1; NAP 1; p125Nap1; membrane-associated protein HEM-2

NCBI Summary for Nckap1

interacts with Nck and may be involved in the downstream signaling of Nck [RGD, Feb 2006]

UniProt Comments for Nckap1

NCKAP1: Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Belongs to the HEM-1/HEM-2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Apoptosis

Cellular Component: focal adhesion; lamellipodium; integral to membrane

Molecular Function: protein binding; protein complex binding; Rac GTPase binding

Biological Process: lamellipodium biogenesis; paraxial mesoderm development; somitogenesis; basal protein localization; zygotic determination of anterior/posterior axis, embryo; protein stabilization; in utero embryonic development; paraxial mesoderm morphogenesis; Rac protein signal transduction; notochord development; mesodermal cell migration; notochord morphogenesis; apical protein localization; embryonic body morphogenesis; regulation of protein localization; embryonic foregut morphogenesis; establishment and/or maintenance of actin cytoskeleton polarity; neural tube closure; embryonic heart tube development; cell migration involved in gastrulation; endoderm development

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-Nckap1 antibody

Products by Pathway	Pathway Diagram
Diurnally Regulated Genes With Circadian Orthologs Pathway antibodies	Diurnally Regulated Genes With Circadian Orthologs Pathway Diagram
Regulation Of Actin Cytoskeleton Pathway antibodies	Regulation Of Actin Cytoskeleton Pathway Diagram
Regulation Of Actin Cytoskeleton Pathway antibodies	Regulation Of Actin Cytoskeleton Pathway Diagram
Regulation Of Actin Cytoskeleton Pathway antibodies	Regulation Of Actin Cytoskeleton Pathway Diagram

Diseases associated with anti-Nckap1 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>3 publications with Nckap1 and Nervous System Diseases
Immune System Diseases Antibodies	>1 publications with Nckap1 and Immune System Diseases
Neoplasms Antibodies	>1 publications with Nckap1 and Neoplasms

Organs/Tissues associated with anti-Nckap1 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>2 publications with Nckap1 and Brain
Kidney Antibodies	>1 publications with Nckap1 and Kidney