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NDUFS3 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS619225

MBS619225 is an antibody targeting NDUFS3. Also known as NDUFS3 (NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kD (NADH-coenzyme Q reductase)). Reactive in Human. Host: Goat. More details

$835 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NDUFS3, Polyclonal Antibody
Full Product Name
NDUFS3 (NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kD (NADH-coenzyme Q reductase))
Product Gene Name
anti-NDUFS3 antibody
Product Synonym Names
Anti -NDUFS3 (NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kD (NADH-coenzyme Q reductase))
Clonality
Polyclonal
Isotype
IgG
Host
Goat
Species Reactivity
Human
Form/Format
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
Purity/Purification
Affinity Purified
Purified by affinity chromatography.
Specificity
Recognizes human NDUFS3. Sequence homology: bovine.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
30,242 Da
Chromosome Location
Chromosome: 11; NC_000011.9 (47600562..47606115). Location: 11p11.11
OMIM
603846
3D Structure
ModBase 3D Structure for O75489
Immunogen
Synthetic peptide corresponding to C-DTRPTVRPRNDVAHK, from the internal region of NDUFS3 human (NP_004542.1).

Product Categories/Family for anti-NDUFS3 antibody

Antibodies; Abs to Enzymes; Dehydrogenase
Applications Tested/Suitable for anti-NDUFS3 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-NDUFS3 antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:4000

Chemiluminescence of anti-NDUFS3 antibody

(0.3ug/ml) staining of Human Frontal Cortex lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-NDUFS3 Polyclonal Antibody – Cat# MBS619225

Other Notes

Small volumes of anti-NDUFS3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NDUFS3. It may not necessarily be applicable to this product.

NCBI GI #
4758788
NCBI GeneID
4722
NCBI Accession #
NP_004542.1
UniProt Primary Accession #
O75489
UniProt Secondary Accession #
Q9UNQ8; B2R9J1
UniProt Related Accession #
O75489; Q53FM7; Q9UF24
GenBank Nucleotide #
NM_004551.2
NCBI Official Full Name
NADH dehydrogenase
NCBI Official Synonym Full Names
NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NCBI Official Symbol
NDUFS3
NCBI Official Synonym Symbols
CI-30
UniProt Protein Name
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
UniProt Synonym Protein Names
Complex I-30kD; CI-30kD; NADH-ubiquinone oxidoreductase 30 kDa subunit
UniProt Gene Name
NDUFS3
UniProt Entry Name
NDUS3_HUMAN
NCBI Protein Information
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; CI-30kD; complex I-30kD; OTTHUMP00000234349; complex I 30kDa subunit; NADH dehydrogenase-ubiquinone 30 kDa subunit; NADH-ubiquinone oxidoreductase 30 kDa subunit

NCBI Summary for NDUFS3

This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.

UniProt Comments for NDUFS3

NDUFS3: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I 30 kDa subunit family.

Protein type: Oxidoreductase; Mitochondrial; Energy Metabolism - oxidative phosphorylation; EC 1.6.99.3; EC 1.6.5.3

Chromosomal Location of Human Ortholog: 11p11.11

Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial membrane; mitochondrial respiratory chain complex I; nucleus

Molecular Function: protein binding; NADH dehydrogenase (ubiquinone) activity; electron carrier activity; NADH dehydrogenase activity

Biological Process: cellular metabolic process; substantia nigra development; mitochondrial electron transport, NADH to ubiquinone; negative regulation of cell growth

Disease: Leigh Syndrome; Mitochondrial Complex I Deficiency
Show more

Research Articles on NDUFS3

1. This protein has been found differentially expressed in the temporal lobe from patients with schizophrenia.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-NDUFS3 antibody

 Products by Pathway  Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Electron Transport Chain Pathway antibodies  Electron Transport Chain Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Oxidative Phosphorylation Pathway antibodies  Oxidative Phosphorylation Pathway Diagram
 Oxidative Phosphorylation Pathway antibodies  Oxidative Phosphorylation Pathway Diagram
 Oxidative Phosphorylation Pathway antibodies  Oxidative Phosphorylation Pathway Diagram
 Parkinson's Disease Pathway antibodies  Parkinson's Disease Pathway Diagram

Diseases associated with anti-NDUFS3 antibody

 Disease Name  Pubmed Publications
 Death Antibodies  >8 publications with NDUFS3 and Death
 Neoplasms Antibodies  >6 publications with NDUFS3 and Neoplasms
 Carcinoma Antibodies  >3 publications with NDUFS3 and Carcinoma
 Urologic Neoplasms Antibodies  >2 publications with NDUFS3 and Urologic Neoplasms
 Skin Diseases Antibodies  >2 publications with NDUFS3 and Skin Diseases
 Breast Neoplasms Antibodies  >2 publications with NDUFS3 and Breast Neoplasms
 Adenocarcinoma Antibodies  >2 publications with NDUFS3 and Adenocarcinoma
 Kidney Neoplasms Antibodies  >2 publications with NDUFS3 and Kidney Neoplasms
 Kidney Diseases Antibodies  >2 publications with NDUFS3 and Kidney Diseases
 Diabetes Mellitus Antibodies  >1 publications with NDUFS3 and Diabetes Mellitus

Organs/Tissues associated with anti-NDUFS3 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4 publications with NDUFS3 and Blood
 Muscle Antibodies  >2 publications with NDUFS3 and Muscle
 Kidney Antibodies  >2 publications with NDUFS3 and Kidney
 Brain Antibodies  >2 publications with NDUFS3 and Brain
 Adipose Tissue Antibodies  >1 publications with NDUFS3 and Adipose Tissue
 Embryonic Tissue Antibodies  >1 publications with NDUFS3 and Embryonic Tissue
 Heart Antibodies  >1 publications with NDUFS3 and Heart
 Liver Antibodies  >1 publications with NDUFS3 and Liver
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