Rabbit Anti-NGDN Polyclonal Antibody – Cat# MBS6325183

NGDN Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the NGDN antibody detected the NGDN protein (arrow).

NGDN Antibody – Rabbit Polyclonal

Name: NGDN Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6325183
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6325183

Neuroguidin is an EIF4E (MIM 133440)-binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al., 2006 [PubMed 16705177]). More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NGDN, Polyclonal Antibody

Full Product Name

NGDN, ID (NGDN, C14orf120, Neuroguidin, EIF4E-binding protein) (FITC)

Product Gene Name

anti-NGDN antibody

Product Synonym Names

NGDN; C14orf120; Neuroguidin; EIF4E-binding protein

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

OMIM

610777

3D Structure

ModBase 3D Structure for Q8NEJ9

Immunogen

NGDN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-165 amino acids from the Central region of human NGDN.

Conjugate

FITC

Note

Preservative Free

Special Handling

Light sensitive

Product Categories/Family for anti-NGDN antibody

Antibodies; Binding Proteins

Applications Tested/Suitable for anti-NGDN antibody

Western Blot (WB), FLISA

Application Notes for anti-NGDN antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-NGDN antibody

Sihn, C.R., et al. Genes Cells 13(8):787-796(2008). Lamesch, P., et al. Genomics 89(3):307-315(2007). Olsen, J.V., et al. Cell 127(3):635-648(2006). Jung, M.Y., et al. Mol. Cell. Biol. 26(11):4277-4287(2006). Nousiainen, M., et al. Proc. Natl. Acad. Sci. U.S.A. 103(14):5391-5396(2006).

Other Notes

Small volumes of anti-NGDN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NGDN purchase

MBS6325183 is an antibody targeting NGDN. Also known as NGDN, ID (NGDN, C14orf120, Neuroguidin, EIF4E-binding protein) (FITC). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NGDN. It may not necessarily be applicable to this product.

NCBI GI #

111038133

NCBI GeneID

25983

NCBI Accession #

NP_056329.1

NCBI Related Accession #

NP_001036100.1

UniProt Primary Accession #

Q8NEJ9

UniProt Related Accession #

Q8NEJ9

GenBank Nucleotide #

NP_056329.1

NCBI Official Full Name

neuroguidin isoform 2

NCBI Official Synonym Full Names

neuroguidin

NCBI Official Symbol

NGDN

NCBI Official Synonym Symbols

NGD; LCP5; CANu1; lpd-2; C14orf120

UniProt Protein Name

Neuroguidin

UniProt Synonym Protein Names

Centromere accumulated nuclear protein 1; CANu1; EIF4E-binding protein

Protein Family

Neuroguidin

UniProt Gene Name

NGDN

UniProt Synonym Gene Names

C14orf120; CANu1

UniProt Entry Name

NGDN_HUMAN

NCBI Protein Information

neuroguidin

UniProt Comments for NGDN

NGDN: Involved in the translational repression of cytoplasmic polyadenylation element (CPE)-containing mRNAs. Belongs to the SAS10 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleolus; RNA-binding; Translation

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: small subunit processome; axon; cytoplasm; dendrite; nucleolus; chromosome, pericentric region; filopodium

Biological Process: regulation of translation; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

Research Articles on NGDN

1. the results of this study in vitro confirmed that NGDN over-expression can increase the sensitivity of human myeloid multidrug-resistant leukemia cells to chemotherapeutic drugs

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.