Rabbit Anti-NMBR Polyclonal Antibody – Cat# MBS6325820

NMBR Antibody (N-term) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the NMBR antibody detected the NMBR protein (arrow).

NMBR Antibody – Rabbit Polyclonal

Name: NMBR Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6325820
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6325820

Neuromedin B receptor binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissue. More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NMBR, Polyclonal Antibody

Full Product Name

NMBR, NT (NMBR, Neuromedin-B receptor, Epididymis tissue protein Li 185a, Neuromedin-B-preferring bombesin receptor) (Biotin)

Product Gene Name

anti-NMBR antibody

Product Synonym Names

NMBR; Neuromedin-B receptor; Epididymis tissue protein Li 185a; Neuromedin-B-preferring bombesin receptor

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

43,435 Da

Chromosome Location

Chromosome: 6; NC_000006.11 (142396745..142409936, complement). Location: 6q21-qter

OMIM

162341

3D Structure

ModBase 3D Structure for P28336

Immunogen

NMBR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human NMBR.

Conjugate

Biotin

Note

Preservative Free

Product Categories/Family for anti-NMBR antibody

Antibodies; Receptors

Applications Tested/Suitable for anti-NMBR antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-NMBR antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-NMBR antibody

Luttrell, L.M. Mol. Biotechnol. 39(3):239-264(2008). Dowal, L., et al. J. Biol. Chem. 281(33):23999-24014(2006). Matusiak, D., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 288 (4), G718-G728 (2005): Lee, S., et al. FEBS Lett. 460(2):263-269(1999). Sainz, E., et al. J. Biol. Chem. 273(26):15927-15932(1998).

Other Notes

Small volumes of anti-NMBR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NMBR purchase

MBS6325820 is an antibody targeting NMBR. Also known as NMBR, NT (NMBR, Neuromedin-B receptor, Epididymis tissue protein Li 185a, Neuromedin-B-preferring bombesin receptor) (Biotin). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NMBR. It may not necessarily be applicable to this product.

NCBI GI #

161484640

NCBI GeneID

4829

NCBI Accession #

NP_002502.2

UniProt Primary Accession #

P28336

UniProt Secondary Accession #

Q5VUK8; E9KL38

UniProt Related Accession #

P28336; AAB27330

GenBank Nucleotide #

NM_002511.2

NCBI Official Full Name

neuromedin-B receptor

NCBI Official Synonym Full Names

neuromedin B receptor

NCBI Official Symbol

NMBR

UniProt Protein Name

Neuromedin-B receptor

UniProt Synonym Protein Names

Epididymis tissue protein Li 185a; Neuromedin-B-preferring bombesin receptor

Protein Family

Neuromedin-B receptor

UniProt Gene Name

NMBR

UniProt Synonym Gene Names

NMB-R

UniProt Entry Name

NMBR_HUMAN

NCBI Protein Information

neuromedin-B receptor; NMB-R; epididymis tissue protein Li 185a; neuromedin-B-preferring bombesin receptor

UniProt Comments for NMBR

NMBR: Receptor for neuromedin-B. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 6q24.1

Cellular Component: integral to plasma membrane; cytoplasm; plasma membrane

Molecular Function: bombesin receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; bombesin receptor signaling pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)

Research Articles on NMBR

1. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NMBR antibody

Reference Product	PubMed Publications
NMB antibody	>12 publications with NMBR and NMB

Pathways associated with anti-NMBR antibody

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram
Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies	Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Peptide GPCRs Pathway antibodies	Peptide GPCRs Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram

Diseases associated with anti-NMBR antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>9 publications with NMBR and Neoplasms
Respiratory Tract Diseases Antibodies	>4 publications with NMBR and Respiratory Tract Diseases
Lung Diseases Antibodies	>3 publications with NMBR and Lung Diseases
Kidney Diseases Antibodies	>2 publications with NMBR and Kidney Diseases
Ovarian Neoplasms Antibodies	>2 publications with NMBR and Ovarian Neoplasms
Genital Neoplasms, Female Antibodies	>2 publications with NMBR and Genital Neoplasms, Female
Edema Antibodies	>1 publications with NMBR and Edema
Nervous System Diseases Antibodies	>1 publications with NMBR and Nervous System Diseases
Heart Diseases Antibodies	>1 publications with NMBR and Heart Diseases
Memory Disorders Antibodies	>1 publications with NMBR and Memory Disorders

Organs/Tissues associated with anti-NMBR antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>7 publications with NMBR and Brain