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NMRAL1 Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS642334

Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP+ levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase (ASS1), the… More details

$880 / 0.05 mg +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
NMRAL1, Polyclonal Antibody
Full Product Name
NMRAL1 (NmrA-Like Family Domain-containing Protein 1, FLJ25918, HSCARG, SDR48A1)
Product Gene Name
Product Synonym Names
Anti -NMRAL1 (NmrA-Like Family Domain-containing Protein 1, FLJ25918, HSCARG, SDR48A1)
Immunogen Sequence
MVDKKLVVVF GGTGAQGGSV ARTLLEDGTF KVRVVTRNPR KKAAKELRLQ GAEVVQGDQD DQVIMELALN GAYATFIVTN YWESCSQEQE VKQGKLLADL ARRLGLHYVV YSGLENIKKL TAGRLAAAHF DGKGEVEEYF RDIGVPMTSV RLPCYFENLL SHFLPQKAPD GKSYLLSLPT GDVPMDGMSV SDLGPVVLSL LKMPEKYVGQ NIGLSTCRHT AEEYAALLTK HTRKVVHDAK MTPEDYEKLG FPGARDLANM FRFYALRPDR DIELTLRLNP KALTLDQWLE QHKGDFNLL
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human NMRAL1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
33,344 Da
Chromosome Location
Chromosome: 16; NC_000016.9 (4511690..4524896, complement). Location: 16p13.3
3D Structure
ModBase 3D Structure for Q9HBL8
Immunogen
Full length human NMRAL1, aa1-299 (NP_065728.1).

Product Categories/Family for anti-NMRAL1 antibody

Applications Tested/Suitable for anti-NMRAL1 antibody
Western Blot (WB)
Application Notes for anti-NMRAL1 antibody
Suitable for use in Western Blot.

Western Blot (WB) of anti-NMRAL1 antibody

Western Blot analysis of NMRAL1 expression in transfected 293T cell line by NMRAL1 polyclonal antibody. Lane 1: HSCARG transfected lysate (32.89kD). Lane 2: Non-transfected lysate.
Mouse Anti-NMRAL1 Polyclonal Antibody – Cat# MBS642334

Other Notes

Small volumes of anti-NMRAL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NMRAL1 purchase

MBS642334 is an antibody targeting NMRAL1. Also known as NMRAL1 (NmrA-Like Family Domain-containing Protein 1, FLJ25918, HSCARG, SDR48A1). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for NMRAL1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
nmrA-like family domain-containing protein 1
NCBI Official Synonym Full Names
NmrA-like family domain containing 1
NCBI Official Symbol
NMRAL1
NCBI Official Synonym Symbols
HSCARG; SDR48A1
UniProt Protein Name
NmrA-like family domain-containing protein 1
UniProt Gene Name
NMRAL1
UniProt Synonym Gene Names
HSCARG
UniProt Entry Name
NMRL1_HUMAN
NCBI Protein Information
nmrA-like family domain-containing protein 1; short chain dehydrogenase/reductase family 48A, member 1

NCBI Summary for NMRAL1

This gene encodes an NADPH sensor protein that preferentially binds to NADPH. The encoded protein also negatively regulates the activity of NF-kappaB in a ubiquitylation-dependent manner. It plays a key role in cellular antiviral response by negatively regulating the interferon response factor 3-mediated expression of interferon beta. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015]
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UniProt Comments for NMRAL1

NMRAL1: disulfide-linked (Probable). Belongs to the NmrA-type oxidoreductase family.

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: perinuclear region of cytoplasm; cytoplasm; nucleus

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-NMRAL1 antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >2 publications with NMRAL1 and Necrosis

Organs/Tissues associated with anti-NMRAL1 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >1 publications with NMRAL1 and Kidney
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