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NOLC1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6325974

Related to nucleologenesis, may play a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It has intrinsic GTPase and ATPase activities. May play an important role in transcription… More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NOLC1, Polyclonal Antibody
Full Product Name
NOLC1, NT (NOLC1, KIAA0035, NS5ATP13, Nucleolar and coiled-body phosphoprotein 1, 140kD nucleolar phosphoprotein, Hepatitis C virus NS5A-transactivated protein 13, Nucleolar 130kD protein, Nucleolar phosphoprotein p130) (Biotin)
Product Gene Name
Product Synonym Names
NOLC1; KIAA0035; NS5ATP13; Nucleolar and coiled-body phosphoprotein 1; 140kD nucleolar phosphoprotein; Hepatitis C virus NS5A-transactivated protein 13; Nucleolar 130kD protein; Nucleolar phosphoprotein p130
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
73,603 Da
Chromosome Location
Chromosome: 10; NC_000010.10 (103911933..103923627). Location: 10q24.32
OMIM
602394
3D Structure
ModBase 3D Structure for Q14978
Immunogen
NOLC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-191 amino acids from the N-terminal region of human NOLC1.
Conjugate
Biotin
Note
Preservative Free
Applications Tested/Suitable for anti-NOLC1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-NOLC1 antibody
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-NOLC1 antibody

NOLC1 Antibody (N-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the NOLC1 antibody detected the NOLC1 protein (arrow).
Rabbit Anti-NOLC1 Polyclonal Antibody – Cat# MBS6325974

Product References and Citations for anti-NOLC1 antibody

Thiry, M., et al. Histochem. Cell Biol. 132(2):129-140(2009). Hwang, Y.C., et al. Am. J. Pathol. 175(1):342-354(2009). Renvoise, B., et al. Hum. Mol. Genet. 18(7):1181-1189(2009). Lee, W.K., et al. Biochem. Biophys. Res. Commun. 376(2):439-444(2008). Tsai, Y.T., et al. J. Biomed. Sci. 15(4):471-486(2008).

Other Notes

Small volumes of anti-NOLC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NOLC1 purchase

MBS6325974 is an antibody targeting NOLC1. Also known as NOLC1, NT (NOLC1, KIAA0035, NS5ATP13, Nucleolar and coiled-body phosphoprotein 1, 140kD nucleolar phosphoprotein, Hepatitis C virus NS5A-transactivated protein 13, Nucleolar 130kD protein, Nucleolar phosphoprotein p130) (Biotin). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NOLC1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
nucleolar and coiled-body phosphoprotein 1
NCBI Official Synonym Full Names
nucleolar and coiled-body phosphoprotein 1
NCBI Official Symbol
NOLC1
NCBI Official Synonym Symbols
P130; NOPP130; NOPP140; NS5ATP13
UniProt Protein Name
Nucleolar and coiled-body phosphoprotein 1
UniProt Synonym Protein Names
140 kDa nucleolar phosphoprotein; Nopp140; Hepatitis C virus NS5A-transactivated protein 13; HCV NS5A-transactivated protein 13; Nucleolar 130 kDa protein; Nucleolar phosphoprotein p130
UniProt Gene Name
NOLC1
UniProt Synonym Gene Names
KIAA0035; NS5ATP13; Nopp140
UniProt Entry Name
NOLC1_HUMAN
NCBI Protein Information
nucleolar and coiled-body phosphoprotein 1; nucleolar protein p130; nucleolar 130 kDa protein; nucleolar phosphoprotein p130; 140 kDa nucleolar phosphoprotein; HCV NS5A-transactivated protein 13; HCV NS5A trans-regulated protein 13; nucleolar and coiled-b

UniProt Comments for NOLC1

NOLC1: Related to nucleologenesis, may play a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It has intrinsic GTPase and ATPase activities. May play an important role in transcription catalyzed by RNA polymerase I. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; Nucleolus; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 10q24.32

Cellular Component: nucleoplasm; Cajal body; cytoplasm; nucleolus

Molecular Function: protein binding; GTP binding; ATP binding

Biological Process: mitosis; cell cycle; rRNA processing; nucleolus organization and biogenesis
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Research Articles on NOLC1

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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