Rabbit Anti-NPBWR1 Polyclonal Antibody – Cat# MBS6326182

NPBWR1 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the NPBWR1 Antibody detected the NPBWR1 protein (arrow).

NPBWR1 Antibody – Rabbit Polyclonal

Name: NPBWR1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6326182
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6326182

NPBWR1 interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B. More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NPBWR1, Polyclonal Antibody

Full Product Name

NPBWR1, CT (NPBWR1, GPR7, Neuropeptides B/W receptor type 1, G-protein coupled receptor 7) (AP)

Product Gene Name

anti-NPBWR1 antibody

Product Synonym Names

NPBWR1; GPR7; Neuropeptides B/W receptor type 1; G-protein coupled receptor 7

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

36,103 Da

OMIM

600730

3D Structure

ModBase 3D Structure for P48145

Immunogen

NPBWR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-250 amino acids from the C-terminal region of human NPBWR1.

Conjugate

Note

Preservative Free

Product Categories/Family for anti-NPBWR1 antibody

Antibodies; G Protein Receptors

Applications Tested/Suitable for anti-NPBWR1 antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-NPBWR1 antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-NPBWR1 antibody

Luttrell, L.M. Mol. Biotechnol. 39(3):239-264(2008). Lambert, N.A. Sci Signal 1 (25), RE5 (2008): Cottrell, S., et al. J. Urol. 177(5):1753-1758(2007). Mazzocchi, G., et al. J. Clin. Endocrinol. Metab. 90(6):3466-3471(2005). Zaratin, P.F., et al. Mol. Cell. Neurosci. 28(1):55-63(2005).

Other Notes

Small volumes of anti-NPBWR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NPBWR1 purchase

MBS6326182 is an antibody targeting NPBWR1. Also known as NPBWR1, CT (NPBWR1, GPR7, Neuropeptides B/W receptor type 1, G-protein coupled receptor 7) (AP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NPBWR1. It may not necessarily be applicable to this product.

NCBI GI #

53828924

NCBI GeneID

2831

NCBI Accession #

NP_005276.2

UniProt Primary Accession #

P48145

UniProt Secondary Accession #

Q6NTC7

UniProt Related Accession #

P48145

GenBank Nucleotide #

NM_005285.3

NCBI Official Full Name

neuropeptides B/W receptor type 1

NCBI Official Synonym Full Names

neuropeptides B/W receptor 1

NCBI Official Symbol

NPBWR1

NCBI Official Synonym Symbols

GPR7

UniProt Protein Name

Neuropeptides B/W receptor type 1

UniProt Synonym Protein Names

G-protein coupled receptor 7

Protein Family

Neuropeptides B/W receptor

UniProt Gene Name

NPBWR1

UniProt Synonym Gene Names

GPR7

UniProt Entry Name

NPBW1_HUMAN

NCBI Protein Information

neuropeptides B/W receptor type 1; neuropeptide B/W receptor 1; G protein-coupled receptor 7; G-protein coupled receptor 7; opioid-somatostatin-like receptor 7

UniProt Comments for NPBWR1

NPBWR1: Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCR

Chromosomal Location of Human Ortholog: 8p22-q21.13

Cellular Component: neuron projection; integral to plasma membrane; plasma membrane; integral to membrane

Molecular Function: neuropeptide binding; protein binding; neuropeptide receptor activity; opioid receptor activity

Biological Process: synaptic transmission; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; neuropeptide signaling pathway; regulation of metabolic process

Research Articles on NPBWR1

1. screening of GPR7 gene mutations among lean and obese subjects revealed a Tyr135Phe allelic variant that is fairly common in the study population. This variant is unlikely to cause a functional derangement of the receptor

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NPBWR1 antibody

Reference Product	PubMed Publications
NPW antibody	>22 publications with NPBWR1 and NPW
NPBWR2 antibody	>14 publications with NPBWR1 and NPBWR2
NPB antibody	>13 publications with NPBWR1 and NPB
POMC antibody	>2 publications with NPBWR1 and POMC
NPY antibody	>1 publications with NPBWR1 and NPY

Pathways associated with anti-NPBWR1 antibody

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies	Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram
Metabolic Disorders Of Biological Oxidation Enzymes Pathway antibodies	Metabolic Disorders Of Biological Oxidation Enzymes Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram

Diseases associated with anti-NPBWR1 antibody

Disease Name	Pubmed Publications
Adenocarcinoma Antibodies	>1 publications with NPBWR1 and Adenocarcinoma
Lung Neoplasms Antibodies	>1 publications with NPBWR1 and Lung Neoplasms
Adrenal Cortex Neoplasms Antibodies	>1 publications with NPBWR1 and Adrenal Cortex Neoplasms

Organs/Tissues associated with anti-NPBWR1 antibody

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>1 publications with NPBWR1 and Lung