Rabbit Anti-NRK Polyclonal Antibody – Cat# MBS6457793

NRK Antibody – Rabbit Polyclonal

Name: NRK Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6457793
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6457793

MBS6457793 is an antibody targeting NRK. Also known as NRK (Nik-Related Protein Kinase, NRK) (FITC). Reactive in Human. Host: Rabbit. More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NRK, Polyclonal Antibody

Full Product Name

NRK (Nik-Related Protein Kinase, NRK) (FITC)

Product Gene Name

anti-NRK antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Specificity

Recognizes human NRK. Species Crossreactivity: human

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer.

Molecular Weight

21,368 Da

OMIM

BX538345 mRNA

3D Structure

ModBase 3D Structure for Q7Z2Y5

Immunogen

KLH conjugated synthetic peptide corresponding to aa721-750 at the Central region of human NRK.

Conjugate

FITC

Note

Preservative Free

Product Categories/Family for anti-NRK antibody

Antibodies; Protein Kinases

Applications Tested/Suitable for anti-NRK antibody

Immunofluorescence (IF), Western Blot (WB)

Application Notes for anti-NRK antibody

IF: 1:10-50
WB: 1:1000
Applications are based on unconjugated antibody.

Product References and Citations for anti-NRK antibody

Ross, M.T., et al. Nature 434(7031):325-337(2005). Nakano, K., et al. Exp. Cell Res. 287(2):219-227(2003).

Other Notes

Small volumes of anti-NRK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NRK. It may not necessarily be applicable to this product.

NCBI GI #

118600963

NCBI GeneID

203447

NCBI Accession #

NP_940867.2

UniProt Primary Accession #

Q7Z2Y5

UniProt Secondary Accession #

Q32ND6; Q5H9K2; Q6ZMP2

UniProt Related Accession #

Q7Z2Y5

GenBank Nucleotide #

NM_198465.3

NCBI Official Full Name

nik-related protein kinase

NCBI Official Synonym Full Names

Nik related kinase

NCBI Official Symbol

NRK

NCBI Official Synonym Symbols

NESK

UniProt Protein Name

Nik-related protein kinase

Protein Family

Nik-related protein kinase

UniProt Gene Name

NRK

NCBI Protein Information

nik-related protein kinase

NCBI Summary for NRK

The mouse ortholog of this gene encodes a protein kinase required for JNK activation. The encoded protein may be involved in the induction of actin polymerization in late embryogenesis.[provided by RefSeq, Jun 2010]

UniProt Comments for NRK

NRK: May phosphorylate cofilin-1 and induce actin polymerization through this process, during the late stages of embryogenesis. Involved in the TNF-alpha-induced signaling pathway. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.7.11.1; Kinase, protein; MSN subfamily; Protein kinase, STE; Protein kinase, Ser/Thr (non-receptor); STE group; STE20 family

Chromosomal Location of Human Ortholog: Xq22.3

Cellular Component: cytoplasm

Molecular Function: ATP binding; MAP kinase kinase kinase kinase activity

Biological Process: activation of JNKK activity; activation of MAPKKK activity; negative regulation of cell proliferation; neuron projection morphogenesis; parturition; regulation of apoptosis; regulation of mitotic cell cycle; stress-activated protein kinase signaling pathway

Research Articles on NRK

1. The results suggest that Nrk suppresses the excessive proliferation of mammary epithelial cells during pregnancy, and the impairment of this regulatory system leads to frequent occurrence of breast tumor in Nrk mutant mice.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NRK antibody

Reference Product	PubMed Publications
CFL1 antibody	>1 publications with NRK and CFL1

Pathways associated with anti-NRK antibody

Products by Pathway	Pathway Diagram
TNF Receptor Signaling Pathway antibodies	TNF Receptor Signaling Pathway Diagram

Diseases associated with anti-NRK antibody

Disease Name	Pubmed Publications
Kidney Diseases Antibodies	>186 publications with NRK and Kidney Diseases
Male Urogenital Diseases Antibodies	>169 publications with NRK and Male Urogenital Diseases
Fibrosis Antibodies	>166 publications with NRK and Fibrosis
Disease Models, Animal Antibodies	>100 publications with NRK and Disease Models, Animal
Necrosis Antibodies	>67 publications with NRK and Necrosis
Acute Kidney Injury Antibodies	>63 publications with NRK and Acute Kidney Injury
Inflammation Antibodies	>42 publications with NRK and Inflammation
Liver Diseases Antibodies	>20 publications with NRK and Liver Diseases
Hypertrophy Antibodies	>15 publications with NRK and Hypertrophy
Lung Neoplasms Antibodies	>9 publications with NRK and Lung Neoplasms

Organs/Tissues associated with anti-NRK antibody

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>1060 publications with NRK and Kidney
Lung Antibodies	>50 publications with NRK and Lung
Connective Tissue Antibodies	>43 publications with NRK and Connective Tissue
Bone Antibodies	>41 publications with NRK and Bone
Brain Antibodies	>40 publications with NRK and Brain
Embryonic Tissue Antibodies	>30 publications with NRK and Embryonic Tissue
Heart Antibodies	>24 publications with NRK and Heart
Ovary Antibodies	>23 publications with NRK and Ovary
Intestine Antibodies	>14 publications with NRK and Intestine
Eye Antibodies	>9 publications with NRK and Eye