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NUDT16 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7602134

MBS7602134 is an antibody targeting NUDT16. Also known as NUDT16 Rabbit Polyclonal. Reactive in Human. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
NUDT16, Polyclonal Antibody
Full Product Name
NUDT16 Rabbit Polyclonal
Product Gene Name
anti-NUDT16 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Molecular Weight
25,259 Da
Immunogen
Nudix (nucleoside diphosphate linked moiety X)-type motif 16
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-NUDT16 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Immunohistochemistry (IHC) of anti-NUDT16 antibody

Immunohistochemistry of paraffin-embedded human kidney tissue slide using MBS7602134 (NUDT16 Antibody) at dilution of 1:50
Rabbit Anti-NUDT16 Polyclonal Antibody – Cat# MBS7602134

Western Blot (WB) of anti-NUDT16 antibody

HeLa cells were subjected to SDS PAGE followed by western blot with MBS7602134 (NUDT16 antibody) at dilution of 1:2500
Rabbit Anti-NUDT16 Polyclonal Antibody, Western Blot (WB) – Cat# MBS7602134

Other Notes

Small volumes of anti-NUDT16 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NUDT16. It may not necessarily be applicable to this product.

NCBI GI #
73909074
NCBI GeneID
131870
NCBI Accession #
AAH31215.2
UniProt Secondary Accession #
Q96N82; B4E3B4; E9PED4; F5GYJ1
UniProt Related Accession #
Q96DE0
NCBI Official Full Name
NUDT16 protein
NCBI Official Synonym Full Names
nudix hydrolase 16
NCBI Official Symbol
NUDT16
UniProt Protein Name
U8 snoRNA-decapping enzyme
UniProt Synonym Protein Names
IDP phosphatase (EC:3.6.1.64
Protein Family
Nudix hydrolase
UniProt Gene Name
NUDT16
UniProt Synonym Gene Names
IDPase; Nudix motif 16
UniProt Entry Name
NUD16_HUMAN
NCBI Protein Information
U8 snoRNA-decapping enzyme

UniProt Comments for NUDT16

NUDT16: RNA-decapping enzyme that binds specifically to U8 snoRNA. Part of the U8 snoRNP complex that is required for the accumulation of mature 5.8S and 28S rRNA. Has diphosphatase activity and removes m7G and m227G caps from U8 snoRNA. Has broad substrate specificity with manganese or cobalt as cofactor and can act on various RNA species (in vitro). Belongs to the Nudix hydrolase family.

Protein type: Hydrolase; EC 3.6.1.62; Nucleolus

Chromosomal Location of Human Ortholog: 3q22.1

Cellular Component: cytoplasm; nucleolus; nucleoplasm; nucleus

Molecular Function: cobalt ion binding; GTP binding; identical protein binding; m7G(5')pppN diphosphatase activity; magnesium ion binding; manganese ion binding; metalloexopeptidase activity; mRNA binding; protein homodimerization activity; snoRNA binding

Biological Process: adenosine to inosine editing; dephosphorylation; IDP catabolic process; mRNA catabolic process; positive regulation of cell proliferation; proteolysis; snoRNA catabolic process
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Research Articles on NUDT16

1. This study details structural and regulatory mechanisms explaining how substrates are selected for hydrolysis by human NUDT16.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-NUDT16 antibody

 Products by Pathway  Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Nucleotides Pathway antibodies  Metabolism Of Nucleotides Pathway Diagram
 Phosphate Bond Hydrolysis By NUDT Proteins Pathway antibodies  Phosphate Bond Hydrolysis By NUDT Proteins Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 RNA Degradation Pathway antibodies  RNA Degradation Pathway Diagram
 RNA Degradation Pathway antibodies  RNA Degradation Pathway Diagram

Diseases associated with anti-NUDT16 antibody

 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >1 publications with NUDT16 and Liver Diseases

Organs/Tissues associated with anti-NUDT16 antibody

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >1 publications with NUDT16 and Embryonic Tissue
 Uterus Antibodies  >1 publications with NUDT16 and Uterus
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