Rabbit Anti-NUPL2 Polyclonal Antibody – Cat# MBS6008194

NUPL2 Antibody (N-term) western blot analysis in 293,K562 cell line lysates (35ug/lane).This demonstrates the NUPL2 antibody detected the NUPL2 protein (arrow).

NUPL2 Antibody – Rabbit Polyclonal

Name: NUPL2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6008194
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6008194

Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope. More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NUPL2, Polyclonal Antibody

Full Product Name

NUPL2, NT (NUPL2, CG1, Nucleoporin-like protein 2, NLP-1, NUP42 homolog, Nucleoporin hCG1)

Product Gene Name

anti-NUPL2 antibody

Product Synonym Names

Anti -NUPL2, NT (NUPL2, CG1, Nucleoporin-like protein 2, NLP-1, NUP42 homolog, Nucleoporin hCG1)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

44,872 Da

Chromosome Location

Chromosome: 7; NC_000007.13 (23221446..23240630). Location: 7p15

3D Structure

ModBase 3D Structure for O15504

Immunogen

NUPL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94~124 amino acids from the N-terminal region of human NUPL2.

Product Categories/Family for anti-NUPL2 antibody

Antibodies; Abs to Proteins

Applications Tested/Suitable for anti-NUPL2 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-NUPL2 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-NUPL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NUPL2 purchase

MBS6008194 is an antibody targeting NUPL2. Also known as NUPL2, NT (NUPL2, CG1, Nucleoporin-like protein 2, NLP-1, NUP42 homolog, Nucleoporin hCG1). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NUPL2. It may not necessarily be applicable to this product.

NCBI GI #

71296916

NCBI GeneID

11097

NCBI Accession #

AAH39333.1

UniProt Primary Accession #

O15504

UniProt Secondary Accession #

Q49AE7; Q9BS49; A4D143; B4DP42

UniProt Related Accession #

O15504

NCBI Official Full Name

NUPL2 protein

NCBI Official Synonym Full Names

nucleoporin like 2

NCBI Official Symbol

NUPL2

NCBI Official Synonym Symbols

CG1; hCG1; NLP-1; NLP_1

UniProt Protein Name

Nucleoporin-like protein 2

UniProt Synonym Protein Names

NLP-1; NUP42 homolog; Nucleoporin hCG1

Protein Family

Nucleoporin-like protein

UniProt Gene Name

NUPL2

UniProt Synonym Gene Names

CG1

UniProt Entry Name

NUPL2_HUMAN

NCBI Protein Information

nucleoporin-like protein 2; H_RG271G13.9; NUP42 homolog; nucleoporin hCG1; nucleoporin-like protein 1

UniProt Comments for NUPL2

NUPL2: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleoporin

Chromosomal Location of Human Ortholog: 7p15

Cellular Component: nucleoplasm; nuclear membrane; cytoplasm; nuclear pore; nucleus; cytosol

Molecular Function: metal ion binding; nuclear export signal receptor activity

Biological Process: mRNA transport; viral reproduction; hexose transport; cytokine and chemokine mediated signaling pathway; carbohydrate metabolic process; mitotic nuclear envelope disassembly; viral transcription; gene expression; pathogenesis; mitotic cell cycle; glucose transport; protein export from nucleus; viral infectious cycle; transmembrane transport

Research Articles on NUPL2

1. NLP1 functions as an accessory factor in CRM1-dependent nuclear protein export

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NUPL2 antibody

Reference Product	PubMed Publications
NUP214 antibody	>2 publications with NUPL2 and NUP214

Pathways associated with anti-NUPL2 antibody

Products by Pathway	Pathway Diagram
Antiviral Mechanism By IFN-stimulated Genes Pathway antibodies	Antiviral Mechanism By IFN-stimulated Genes Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Cell Cycle, Mitotic Pathway antibodies	Cell Cycle, Mitotic Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Export Of Viral Ribonucleoproteins From Nucleus Pathway antibodies	Export Of Viral Ribonucleoproteins From Nucleus Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Glucose Transport Pathway antibodies	Glucose Transport Pathway Diagram
HIV Infection Pathway antibodies	HIV Infection Pathway Diagram
HIV Life Cycle Pathway antibodies	HIV Life Cycle Pathway Diagram

Organs/Tissues associated with anti-NUPL2 antibody

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>1 publications with NUPL2 and Bone
Blood Antibodies	>1 publications with NUPL2 and Blood