Rabbit Anti-PAN2 Polyclonal Antibody – Cat# MBS6330641

PAN2 Antibody (C-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the PAN2 antibody detected the PAN2 protein (arrow).

PAN2 Antibody – Rabbit Polyclonal

Name: PAN2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6330641
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6330641

This gene encodes a deadenylase that functions as the catalytic subunit of the polyadenylate binding protein dependent poly(A) nuclease complex. The encoded protein is a magnesium dependent 3' to 5' exoribonuclease that is involved in the degradation of… More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PAN2, Polyclonal Antibody

Full Product Name

PAN2, CT (PAN2, KIAA0710, USP52, PAB-dependent poly(A)-specific ribonuclease subunit 2, Inactive ubiquitin carboxyl-terminal hydrolase 52) (Azide free) (HRP)

Product Gene Name

anti-PAN2 antibody

Product Synonym Names

PAN2; KIAA0710; USP52; PAB-dependent poly(A)-specific ribonuclease subunit 2; Inactive ubiquitin carboxyl-terminal hydrolase 52

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

3D Structure

ModBase 3D Structure for Q504Q3

Immunogen

PAN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 859-888 amino acids from the C-terminal region of human PAN2.

Conjugate

HRP

Note

Preservative Free

Product Categories/Family for anti-PAN2 antibody

Antibodies; Enzymes; Ribonuclease

Applications Tested/Suitable for anti-PAN2 antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-PAN2 antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-PAN2 antibody

Bailey, S.D., et al. Diabetes Care (2010). In press: Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009). Funakoshi, Y., et al. Genes Dev. 21(23):3135-3148(2007). Ezzeddine, N., et al. Mol. Cell. Biol. 27(22):7791-7801(2007). Yamashita, A., et al. Nat. Struct. Mol. Biol. 12(12):1054-1063(2005).

Other Notes

Small volumes of anti-PAN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PAN2 purchase

MBS6330641 is an antibody targeting PAN2. Also known as PAN2, CT (PAN2, KIAA0710, USP52, PAB-dependent poly(A)-specific ribonuclease subunit 2, Inactive ubiquitin carboxyl-terminal hydrolase 52) (Azide free) (HRP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PAN2. It may not necessarily be applicable to this product.

NCBI GI #

188536112

NCBI GeneID

9924

NCBI Accession #

NP_055686.3

NCBI Related Accession #

NP_001120932.1

UniProt Primary Accession #

Q504Q3

UniProt Related Accession #

Q504Q3

GenBank Nucleotide #

NP_055686.3

NCBI Official Full Name

PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform 3

NCBI Official Synonym Full Names

poly(A) specific ribonuclease subunit PAN2

NCBI Official Symbol

PAN2

NCBI Official Synonym Symbols

USP52

UniProt Protein Name

PAB-dependent poly(A)-specific ribonuclease subunit PAN2

UniProt Synonym Protein Names

Inactive ubiquitin carboxyl-terminal hydrolase 52; PAB1P-dependent poly(A)-nuclease; PAN deadenylation complex catalytic subunit 2

Protein Family

PAB-dependent poly(A)-specific ribonuclease

UniProt Gene Name

PAN2

UniProt Synonym Gene Names

hPan2

UniProt Entry Name

PAN2_HUMAN

NCBI Protein Information

PAN2-PAN3 deadenylation complex catalytic subunit PAN2

Research Articles on PAN2

1. USP52 is a bona fide ubiquitin-specific protease, and USP52 promotes ASF1A deubiquitination and stabilization.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.