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PBP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8532553

MBS8532553 is an antibody targeting PBP. Also known as PBP Polyclonal Antibody. Reactive in Human. Host: Rabbit. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PBP, Polyclonal Antibody
Full Product Name
PBP Polyclonal Antibody
Product Gene Name
Product Synonym Names
Platelet basic protein; PBP; C-X-C motif chemokine 7; Leukocyte-derived growth factor; LDGF; Macrophage-derived growth factor; MDGF; Small-inducible cytokine B7; Connective tissue-activating peptide III; CTAP-III; LA-PF4; Low-affinity platelet factor IV; TC-2; Connective tissue-activating peptide III(1-81; CTAP-III(1-81); Beta-thromboglobulin; Beta-TG; Neutrophil-activating peptide 2(74; NAP-2(74); Neutrophil-activating peptide 2(73; NAP-2(73); Neutrophil-activating peptide 2; NAP-2; TC-1; Neutrophil-activating peptide 2(1-66; NAP-2(1-66); Neutrophil-activating peptide 2(1-63; NAP-2(1-63); PPBP; CTAP3; CXCL7; SCYB7; TGB1; THBGB1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
13,894 Da
OMIM
121010
3D Structure
ModBase 3D Structure for P02775
Immunogen
Synthetic peptide from human protein at AA range: 71-120
Storage Buffer
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PBP antibody
Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
Application Notes for anti-PBP antibody
IHC-p: 1:50-200
ELISA: 1:10000-20000

Other Notes

Small volumes of anti-PBP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PBP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
platelet basic protein preproprotein
NCBI Official Synonym Full Names
pro-platelet basic protein
NCBI Official Symbol
PPBP
NCBI Official Synonym Symbols
PBP; TC1; TC2; TGB; LDGF; MDGF; TGB1; B-TG1; CTAP3; CXCL7; NAP-2; SCYB7; THBGB; LA-PF4; THBGB1; Beta-TG; CTAPIII; CTAP-III
UniProt Protein Name
Platelet basic protein
UniProt Synonym Protein Names
C-X-C motif chemokine 7; Leukocyte-derived growth factor; LDGF
UniProt Gene Name
PPBP
UniProt Synonym Gene Names
CTAP3; CXCL7; SCYB7; TGB1; THBGB1; PBP; LDGF; MDGF; CTAP-III; CTAP-III(1-81); Beta-TG; NAP-2(74); NAP-2(73); NAP-2; NAP-2(1-66); NAP-2(1-63)
NCBI Protein Information
platelet basic protein

NCBI Summary for PBP

The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity. [provided by RefSeq, Nov 2014]
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UniProt Comments for PBP

LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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