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PDCL3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6332060

This gene encodes a member of the phosducin-like protein family and is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin. Members of the phosducin-like protein family have been shown to… More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PDCL3, Polyclonal Antibody
Full Product Name
PDCL3, NT (PDCL3, VIAF1, Phosducin-like protein 3, HTPHLP, PhPL3, Viral IAP-associated factor 1) (Azide free) (HRP)
Product Gene Name
Product Synonym Names
PDCL3; VIAF1; Phosducin-like protein 3; HTPHLP; PhPL3; Viral IAP-associated factor 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
27,614 Da
OMIM
611678
3D Structure
ModBase 3D Structure for Q9H2J4
Immunogen
PDCL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-68 amino acids from the N-terminal region of human PDCL3.
Conjugate
HRP
Note
Preservative Free

Product Categories/Family for anti-PDCL3 antibody

Applications Tested/Suitable for anti-PDCL3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-PDCL3 antibody
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-PDCL3 antibody

PDCL3 Antibody (N-term) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the PDCL3 antibody detected the PDCL3 protein (arrow).
Rabbit Anti-PDCL3 Polyclonal Antibody – Cat# MBS6332060

Product References and Citations for anti-PDCL3 antibody

Stirling, P.C., et al. Mol. Biol. Cell 18(6):2336-2345(2007). Lamesch, P., et al. Genomics 89(3):307-315(2007). Wilkinson, J.C., et al. J. Biol. Chem. 279(49):51091-51099(2004). Lopez, P., et al. J. Biol. Chem. 278(3):1751-1757(2003).

Other Notes

Small volumes of anti-PDCL3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PDCL3 purchase

MBS6332060 is an antibody targeting PDCL3. Also known as PDCL3, NT (PDCL3, VIAF1, Phosducin-like protein 3, HTPHLP, PhPL3, Viral IAP-associated factor 1) (Azide free) (HRP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PDCL3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
phosducin-like protein 3
NCBI Official Synonym Full Names
phosducin like 3
NCBI Official Symbol
PDCL3
NCBI Official Synonym Symbols
VIAF; PHLP3; VIAF1; HTPHLP; PHLP2A
UniProt Protein Name
Phosducin-like protein 3
UniProt Synonym Protein Names
HTPHLP; PhPL3; Viral IAP-associated factor 1; VIAF-1
UniProt Gene Name
PDCL3
UniProt Synonym Gene Names
PhLP2A; VIAF1; VIAF-1
UniProt Entry Name
PDCL3_HUMAN
NCBI Protein Information
phosducin-like protein 3

UniProt Comments for PDCL3

PDCL3: Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination. Belongs to the phosducin family.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 2q11.2

Cellular Component: cytoplasm

Molecular Function: protein binding; vascular endothelial growth factor receptor 2 binding

Biological Process: positive regulation of angiogenesis; protein folding; viral reproduction; apoptosis; positive regulation of endothelial cell proliferation; angiogenesis; regulation of peptidyl-tyrosine phosphorylation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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