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PLCL1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6493287

MBS6493287 is an antibody targeting PLCL1. Also known as PLCL1, NT (Phospholipase C-related But Catalytically Inactive Protein, PRIP, Phospholipase C-deleted In Lung Carcinoma, Inactive Phospholipase C-like Protein 1, PLC-L1) (MaxLight 750). Reactive in… More details

$1025 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PLCL1, Polyclonal Antibody
Full Product Name
PLCL1, NT (Phospholipase C-related But Catalytically Inactive Protein, PRIP, Phospholipase C-deleted In Lung Carcinoma, Inactive Phospholipase C-like Protein 1, PLC-L1) (MaxLight 750)
Product Gene Name
anti-PLCL1 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.
Purity/Purification
Purified by Immunoaffinity chromatography.
Specificity
Recognizes human PLCL1.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
113.0122
OMIM
600597
3D Structure
ModBase 3D Structure for Q15111
Immunogen
Synthetic peptide selected from the N-terminal region of human PLCL1 (KLH).
Conjugate
MaxLight750
Note
Preservative Free

Product Categories/Family for anti-PLCL1 antibody

Antibodies; Enzymes; Phospholipase
Applications Tested/Suitable for anti-PLCL1 antibody
Western Blot (WB), FLISA
Application Notes for anti-PLCL1 antibody
WB: 1:100-1:500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-PLCL1 antibody

1. Liu, Y.Z., et.al., PLoS ONE 3(9), E3160 (2008).

Other Notes

Small volumes of anti-PLCL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PLCL1. It may not necessarily be applicable to this product.

NCBI GI #
167900450
NCBI Accession #
NP_006217.2
UniProt Primary Accession #
Q15111
GenBank Nucleotide #
NP_006217.2
NCBI Official Full Name
phospholipase C-like 1 isoform b
UniProt Protein Name
Inactive phospholipase C-like protein 1
UniProt Synonym Protein Names
Phospholipase C-deleted in lung carcinoma; Phospholipase C-related but catalytically inactive protein; PRIP
Protein Family
Inactive phospholipase C-like protein
UniProt Gene Name
PLCL1
UniProt Synonym Gene Names
PLC-L1; PRIP
UniProt Entry Name
PLCL1_HUMAN

UniProt Comments for PLCL1

PLCL1: a protein closely related to phospholipase C-d1 (PLC-d1) but catalytically inactive. First identified as a novel inositol 1,4,5-trisphosphate binding protein. Has a number of binding partners including protein phosphatase (PP1 and 2A), GABA(A) receptor associated protein, and the beta subunits of GABA(A) receptors, in addition to inositol 1,4,5-trisphosphate. Plays an important role in controlling the dynamics of GABA(A) receptor phosphorylation through PP1 binding and, therefore, the efficacy of synaptic inhibition mediated by these receptors.

Protein type: Phospholipase

Chromosomal Location of Human Ortholog: 2q33

Cellular Component: cytoplasm; plasma membrane

Molecular Function: signal transducer activity; GABA receptor binding; phosphoinositide phospholipase C activity; phospholipase C activity

Biological Process: regulation of peptidyl-serine phosphorylation; lipid metabolic process; regulation of synaptic transmission, GABAergic; gamma-aminobutyric acid signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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