Rabbit Anti-POLR2B Polyclonal Antibody – Cat# MBS6335686

POLR2B Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the POLR2B antibody detected the POLR2B protein (arrow).

POLR2B Antibody – Rabbit Polyclonal

Name: POLR2B Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6335686
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6335686

This gene encodes the second largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with at least two other polymerase subunits, forms a structure within the polymerase that… More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

POLR2B, Polyclonal Antibody

Full Product Name

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2) (AP)

Product Gene Name

anti-POLR2B antibody

Product Synonym Names

POLR2B; DNA-directed RNA polymerase II subunit RPB2; DNA-directed RNA polymerase II 140kD polypeptide; DNA-directed RNA polymerase II subunit B; RNA polymerase II subunit 2; RNA polymerase II subunit B2

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

133,897 Da

OMIM

180661

3D Structure

ModBase 3D Structure for P30876

Immunogen

POLR2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 796-826 amino acids from the Central region of human POLR2B.

Conjugate

Note

Preservative Free

Product Categories/Family for anti-POLR2B antibody

Antibodies; Enzymes; Polymerase

Applications Tested/Suitable for anti-POLR2B antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-POLR2B antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-POLR2B antibody

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Michiels, S., et al. Carcinogenesis 30(5):763-768(2009). Tu, S., et al. Nat. Struct. Mol. Biol. 15(4):419-421(2008). Lee, J.H., et al. Mol. Cell. Biol. 28(2):609-618(2008). Yamaguchi, Y., et al. Genes Cells 12(7):863-875(2007).

Other Notes

Small volumes of anti-POLR2B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for POLR2B purchase

MBS6335686 is an antibody targeting POLR2B. Also known as POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2) (AP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for POLR2B. It may not necessarily be applicable to this product.

NCBI GI #

4505941

NCBI GeneID

5431

NCBI Accession #

NP_000929.1

UniProt Primary Accession #

P30876

UniProt Secondary Accession #

Q8IZ61; A8K1A8

UniProt Related Accession #

P30876; AAB23139

GenBank Nucleotide #

NM_000938.1

NCBI Official Full Name

DNA-directed RNA polymerase II subunit RPB2

NCBI Official Synonym Full Names

polymerase (RNA) II (DNA directed) polypeptide B, 140kDa

NCBI Official Symbol

POLR2B

NCBI Official Synonym Symbols

RPB2; POL2RB; hsRPB2; hRPB140

UniProt Protein Name

DNA-directed RNA polymerase II subunit RPB2

UniProt Synonym Protein Names

DNA-directed RNA polymerase II 140 kDa polypeptide; DNA-directed RNA polymerase II subunit B; RNA polymerase II subunit 2; RNA polymerase II subunit B2

Protein Family

DNA-directed RNA polymerase

UniProt Gene Name

POLR2B

UniProt Entry Name

RPB2_HUMAN

NCBI Protein Information

DNA-directed RNA polymerase II subunit RPB2; RNA polymerase II subunit 2; RNA polymerase II subunit B2; DNA-directed RNA polymerase II subunit B; DNA-directed RNA polymerase II 140 kDa polypeptide; DNA directed RNA polymerase II 140 kDa polypeptide, RNA p

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-POLR2B antibody

Reference Product	PubMed Publications
POLR2A antibody	>2 publications with POLR2B and POLR2A

Pathways associated with anti-POLR2B antibody

Products by Pathway	Pathway Diagram
Abortive Elongation Of HIV-1 Transcript In The Absence Of Tat Pathway antibodies	Abortive Elongation Of HIV-1 Transcript In The Absence Of Tat Pathway Diagram
DNA Repair Pathway antibodies	DNA Repair Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Dual Incision Reaction In TC-NER Pathway antibodies	Dual Incision Reaction In TC-NER Pathway Diagram
Epstein-Barr Virus Infection Pathway antibodies	Epstein-Barr Virus Infection Pathway Diagram
Epstein-Barr Virus Infection Pathway antibodies	Epstein-Barr Virus Infection Pathway Diagram
Eukaryotic Transcription Initiation Pathway antibodies	Eukaryotic Transcription Initiation Pathway Diagram
Formation Of HIV-1 Elongation Complex Containing HIV-1 Tat Pathway antibodies	Formation Of HIV-1 Elongation Complex Containing HIV-1 Tat Pathway Diagram
Formation Of HIV-1 Elongation Complex In The Absence Of HIV-1 Tat Pathway antibodies	Formation Of HIV-1 Elongation Complex In The Absence Of HIV-1 Tat Pathway Diagram
Formation Of RNA Pol II Elongation Complex Pathway antibodies	Formation Of RNA Pol II Elongation Complex Pathway Diagram

Organs/Tissues associated with anti-POLR2B antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>2 publications with POLR2B and Blood
Lung Antibodies	>1 publications with POLR2B and Lung
Embryonic Tissue Antibodies	>1 publications with POLR2B and Embryonic Tissue
Brain Antibodies	>1 publications with POLR2B and Brain