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PPBP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9415615

The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA… More details

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Product Overview

Online Datasheet in PDF
Product Name
PPBP, Polyclonal Antibody
Full Product Name
PPBP Antibody
Product Gene Name
Product Synonym Names
PBP; TC1; TC2; TGB; LDGF; MDGF; TGB1; B-TG1; CTAP3; CXCL7; NAP-2; SCYB7; THBGB; LA-PF4; THBGB1; Beta-TG; CTAPIII; CTAP-III
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Purity/Purification
Antigen Affinity Purification
Concentration
2.1 mg/ml (lot specific)
Specificity
The antibody detects endogenous levels of total PPBP protein.
Preparation and Storage
Store at -20 degree C
Molecular Weight
13,894 Da
OMIM
121010
3D Structure
ModBase 3D Structure for P02775
Immunogen
Synthetic peptide of human PPBP
Immunogen Type
Peptide

Product Categories/Family for anti-PPBP antibody

Applications Tested/Suitable for anti-PPBP antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PPBP antibody
Western Blot: 1:1000-1:5000
Immunohistochemistry: 1:25-1:100

Western Blot (WB) of anti-PPBP antibody

Gel: 12%SDS-PAGE Lysate: 40 μ g Lane: Human plasma solution Primary antibody: 1/500 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute
Rabbit Anti-PPBP Polyclonal Antibody – Cat# MBS9415615

Immunohistochemistry (IHC) of anti-PPBP antibody

Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/30,
Rabbit Anti-PPBP Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9415615

Other Notes

Small volumes of anti-PPBP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PPBP purchase

MBS9415615 is an antibody targeting PPBP. Also known as PPBP Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PPBP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
platelet basic protein preproprotein
NCBI Official Synonym Full Names
pro-platelet basic protein
NCBI Official Symbol
PPBP
NCBI Official Synonym Symbols
PBP; TC1; TC2; TGB; LDGF; MDGF; TGB1; B-TG1; CTAP3; CXCL7; NAP-2; SCYB7; THBGB; LA-PF4; THBGB1; Beta-TG; CTAPIII; CTAP-III
UniProt Protein Name
Platelet basic protein
UniProt Synonym Protein Names
C-X-C motif chemokine 7; Leukocyte-derived growth factor; LDGF
UniProt Gene Name
PPBP
UniProt Synonym Gene Names
CTAP3; CXCL7; SCYB7; TGB1; THBGB1; PBP; LDGF; MDGF; CTAP-III; CTAP-III(1-81); Beta-TG; NAP-2(74); NAP-2(73); NAP-2; NAP-2(1-66); NAP-2(1-63)
UniProt Entry Name
CXCL7_HUMAN
NCBI Protein Information
platelet basic protein

UniProt Comments for PPBP

LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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