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PPIC Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6336259

PPIC is a member of the peptidyl-prolyl cis-trans isomerase (PPIase)) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. Similar to other PPIases, this protein can bind… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PPIC, Polyclonal Antibody
Full Product Name
PPIC, ID (PPIC, CYPC, Peptidyl-prolyl cis-trans isomerase C, Cyclophilin C, Rotamase C) (APC)
Product Gene Name
Product Synonym Names
PPIC; CYPC; Peptidyl-prolyl cis-trans isomerase C; Cyclophilin C; Rotamase C
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
22,763 Da
OMIM
123842
3D Structure
ModBase 3D Structure for P45877
Immunogen
PPIC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68~97 amino acids from the Center region of human PPIC.
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive

Product Categories/Family for anti-PPIC antibody

Applications Tested/Suitable for anti-PPIC antibody
Flow Cytometry (FC/FACS), FLISA, Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-PPIC antibody
FC/FACS: 1:10-50
FLISA: 1:1,000
IHC: 1:50-100
WB: 1:100-500
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-PPIC antibody

Western blot analysis of PPIC Antibody (Center) in Hela cell line lysates (35ug/lane). PPIC (arrow) was detected using the purified Pab.
Rabbit Anti-PPIC Polyclonal Antibody – Cat# MBS6336259

Immunohistochemistry (IHC) of anti-PPIC antibody

Formalin-fixed and paraffin-embedded human brain tissue reacted with PPIC Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-PPIC Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6336259

Flow Cytometry (FC/FACS) of anti-PPIC antibody

PPIC Antibody (Center) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-PPIC Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS6336259

Product References and Citations for anti-PPIC antibody

Vasan, R.S. JAMA 302 (2), 168-178 (2009). Lim, J. Cell 125 (4), 801-814 (2006). Trahey, M. Proc. Natl. Acad. Sci. U.S.A. 96 (6), 3006-3011 (1999).

Other Notes

Small volumes of anti-PPIC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PPIC purchase

MBS6336259 is an antibody targeting PPIC. Also known as PPIC, ID (PPIC, CYPC, Peptidyl-prolyl cis-trans isomerase C, Cyclophilin C, Rotamase C) (APC). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PPIC. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
peptidyl-prolyl cis-trans isomerase C
NCBI Official Synonym Full Names
peptidylprolyl isomerase C
NCBI Official Symbol
PPIC
NCBI Official Synonym Symbols
CYPC
UniProt Protein Name
Peptidyl-prolyl cis-trans isomerase C
UniProt Synonym Protein Names
Cyclophilin C; Rotamase C
UniProt Gene Name
PPIC
UniProt Synonym Gene Names
CYPC; PPIase C
UniProt Entry Name
PPIC_HUMAN
NCBI Protein Information
peptidyl-prolyl cis-trans isomerase C

UniProt Comments for PPIC

PPIC: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Belongs to the cyclophilin-type PPIase family.

Protein type: Cyclophilin; EC 5.2.1.8; Isomerase

Chromosomal Location of Human Ortholog: 5q23.2

Molecular Function: cyclosporin A binding; peptidyl-prolyl cis-trans isomerase activity; protein binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PPIC antibody

 Reference Product  PubMed Publications
 P4HB antibody  >1 publications with PPIC and P4HB
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