Rabbit Anti-PRLHR Polyclonal Antibody – Cat# MBS6337482

PRLHR Antibody (C-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the PRLHR antibody detected the PRLHR protein (arrow).

PRLHR Antibody – Rabbit Polyclonal

Name: PRLHR Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6337482
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6337482

PRLHR is a 7-transmembrane domain receptor for prolactin-releasing hormone (PRLH; MIM 602663) that is highly expressed in anterior pituitary (Ozawa et al., 2002 [PubMed 11923475]). More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PRLHR, Polyclonal Antibody

Full Product Name

PRLHR, CT (PRLHR, GPR10, GR3, Prolactin-releasing peptide receptor, G-protein coupled receptor 10, hGR3) (FITC)

Product Gene Name

anti-PRLHR antibody

Product Synonym Names

PRLHR; GPR10; GR3; Prolactin-releasing peptide receptor; G-protein coupled receptor 10; hGR3

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

41,121 Da

Chromosome Location

Chromosome: 10; NC_000010.10 (120352916..120355160, complement). Location: 10q26.13

OMIM

600895

3D Structure

ModBase 3D Structure for P49683

Immunogen

PRLHR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-312 amino acids from the C-terminal region of human PRLHR.

Conjugate

FITC

Note

Preservative Free

Special Handling

Light sensitive

Product Categories/Family for anti-PRLHR antibody

Antibodies; G Protein Receptors

Applications Tested/Suitable for anti-PRLHR antibody

Western Blot (WB), FLISA

Application Notes for anti-PRLHR antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-PRLHR antibody

Bailey, S.D., et al. Diabetes Care (2010). In press: Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009). Lagerstrom, M.C., et al. Genomics 85(6):688-703(2005). Ellacott, K.L., et al. Peptides 26(4):675-681(2005). Deloukas, P., et al. Nature 429(6990):375-381(2004).

Other Notes

Small volumes of anti-PRLHR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PRLHR purchase

MBS6337482 is an antibody targeting PRLHR. Also known as PRLHR, CT (PRLHR, GPR10, GR3, Prolactin-releasing peptide receptor, G-protein coupled receptor 10, hGR3) (FITC). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PRLHR. It may not necessarily be applicable to this product.

NCBI GI #

4758474

NCBI GeneID

2834

NCBI Accession #

NP_004239.1

UniProt Primary Accession #

P49683

UniProt Secondary Accession #

O75194; Q502U8; Q5VXR9

UniProt Related Accession #

P49683

GenBank Nucleotide #

NM_004248.2

NCBI Official Full Name

prolactin-releasing peptide receptor

NCBI Official Synonym Full Names

prolactin releasing hormone receptor

NCBI Official Symbol

PRLHR

NCBI Official Synonym Symbols

GR3; GPR10; PrRPR

UniProt Protein Name

Prolactin-releasing peptide receptor

UniProt Synonym Protein Names

G-protein coupled receptor 10; hGR3

Protein Family

Prolactin-releasing peptide receptor

UniProt Gene Name

PRLHR

UniProt Synonym Gene Names

GPR10; GR3; PrRP receptor; PrRPR

UniProt Entry Name

PRLHR_HUMAN

NCBI Protein Information

prolactin-releasing peptide receptor; hGR3; prRP receptor; G protein-coupled receptor 10; G-protein coupled receptor 10; prolactin releasing peptide receptor; prolactin-releasing hormone receptor

UniProt Comments for PRLHR

GPR10: Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and pain-signal processing. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 10q26.13

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; protein binding; neuropeptide receptor activity; neuropeptide Y receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; neuropeptide signaling pathway; hormone metabolic process; feeding behavior; female pregnancy

Research Articles on PRLHR

1. demonstrate previously unrecognized roles for GPR10 and its upstream regulator REST in the pathogenesis of uterine fibroids

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PRLHR antibody

Reference Product	PubMed Publications
PRLH antibody	>9 publications with PRLHR and PRLH
PICK1 antibody	>1 publications with PRLHR and PICK1

Pathways associated with anti-PRLHR antibody

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram

Diseases associated with anti-PRLHR antibody

Disease Name	Pubmed Publications
Diabetes Mellitus Antibodies	>1 publications with PRLHR and Diabetes Mellitus
Hyperplasia Antibodies	>1 publications with PRLHR and Hyperplasia

Organs/Tissues associated with anti-PRLHR antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>11 publications with PRLHR and Brain
Adrenal Gland Antibodies	>2 publications with PRLHR and Adrenal Gland
Muscle Antibodies	>1 publications with PRLHR and Muscle