Rabbit Anti-PSMD13 Polyclonal Antibody – Cat# MBS8104029

Anti-PSMD13 rabbit polyclonal antibody at 1:500 dilution
Lane A: 293T Whole Cell Lysate
Lane B: HeLa Whole Cell Lysate
Lysates/proteins at 30 ug per lane.
Secondary
Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution.
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size:43 kDa
Observed band size:45 kDa

PSMD13 Antibody – Rabbit Polyclonal

Name: PSMD13 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS8104029
Price: 370 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8104029

PSMD13 (Proteasome 26S Subunit, Non-ATPase 13) is a Protein Coding gene. The PSMD13 gene, located on 11p15.5, is conserved in chimpanzee, dog, cow, mouse, rat, and chicken, etc. This gene encodes a non-ATPase subunit of the 19S regulator. PSMD13, a newly… More details

$370 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PSMD13, Polyclonal Antibody

Full Product Name

Anti-PSMD13 Antibody, Rabbit Polyclonal

Product Gene Name

anti-PSMD13 antibody

Product Synonym Names

PSMD13 Antibody, Rabbit PAb, Antigen Affinity Purified; proteasome (prosome, macropain) 26S subunit, non-ATPase, 13; Anti-HSPC027 Antibody; Anti-p40.5 Antibody; Anti-Rpn9 Antibody; Anti-S11 Antibody

Clonality

Polyclonal

Isotype

Rabbit IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid; PBS, pH7.0 with 0.03% Proclin300

Purity/Purification

Protein A & Antigen Affinity

Specificity

Human PSMD13

Preparation and Storage

This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.

Molecular Weight

45.3kDa (399aa)

OMIM

AB009398 mRNA

3D Structure

ModBase 3D Structure for Q9UNM6

Immunogen

A synthetic peptide corresponding to the center region of the Human PSMD13

Conjugation

Unconjugated

Preparation

Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human PSMD13, and purified by antigen affinity chromatography.

Applications Tested/Suitable for anti-PSMD13 antibody

Western Blot (WB)

Application Notes for anti-PSMD13 antibody

WB: 1:500-1:2000

Product References and Citations for anti-PSMD13 antibody

Li S, et al. (2015) Temperature-sensitive retinoid isomerase activity of rpe65 mutants associated with leber congenital amaurosis. J Biochem 158 (2): 115-125.Li S, et al. (2014) Rescue of enzymatic function for disease-associated rpe65 proteins containing various missense mutations in non-active sites. J Biol Chem 289 (27): 18943-18956.Bellizzi D, et al. (2007) Characterization of a bidirectional promoter shared between two human genes related to aging: Sirt3 and psmd13. Genomics 89 (1): 143-150.

Other Notes

Small volumes of anti-PSMD13 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PSMD13 purchase

MBS8104029 is an antibody targeting PSMD13. Also known as Anti-PSMD13 Antibody, Rabbit Polyclonal. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PSMD13. It may not necessarily be applicable to this product.

NCBI GI #

157502193

NCBI GeneID

5719

NCBI Accession #

NP_002808

UniProt Primary Accession #

Q9UNM6

UniProt Secondary Accession #

O75831; Q53XU2; Q9UNV3; B3KT15

UniProt Related Accession #

Q9UNM6

GenBank Nucleotide #

NM_002817.3

NCBI Official Full Name

26S proteasome non-ATPase regulatory subunit 13 isoform 1

NCBI Official Synonym Full Names

proteasome 26S subunit, non-ATPase 13

NCBI Official Symbol

PSMD13

NCBI Official Synonym Symbols

S11; Rpn9; p40.5; HSPC027

UniProt Protein Name

26S proteasome non-ATPase regulatory subunit 13

UniProt Synonym Protein Names

26S proteasome regulatory subunit RPN9; 26S proteasome regulatory subunit S11; 26S proteasome regulatory subunit p40.5

Protein Family

26S proteasome non-ATPase regulatory

UniProt Gene Name

PSMD13

NCBI Protein Information

26S proteasome non-ATPase regulatory subunit 13

NCBI Summary for PSMD13

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

UniProt Comments for PSMD13

Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

Research Articles on PSMD13

1. Studies have found significant associations of the treatment response with the 26S proteasome non-ATPase subunit 9 (PSMD9), proteasome alpha type 7 subunit (PSMA7) and PSMD13 genes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PSMD13 antibody

Products by Pathway	Pathway Diagram
ABC Transporter Disorders Pathway antibodies	ABC Transporter Disorders Pathway Diagram
ABC-family Proteins Mediated Transport Pathway antibodies	ABC-family Proteins Mediated Transport Pathway Diagram
APC/C-mediated Degradation Of Cell Cycle Proteins Pathway antibodies	APC/C-mediated Degradation Of Cell Cycle Proteins Pathway Diagram
APC/C:Cdc20 Mediated Degradation Of Securin Pathway antibodies	APC/C:Cdc20 Mediated Degradation Of Securin Pathway Diagram
APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies	APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram
APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway antibodies	APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway Diagram
APC:Cdc20 Mediated Degradation Of Cell Cycle Proteins Prior To Satisfation Of The Cell Cycle Checkpoint Pathway antibodies	APC:Cdc20 Mediated Degradation Of Cell Cycle Proteins Prior To Satisfation Of The Cell Cycle Checkpoint Pathway Diagram
ARMS-mediated Activation Pathway antibodies	ARMS-mediated Activation Pathway Diagram
AUF1 (hnRNP D0) Binds And Destabilizes MRNA Pathway antibodies	AUF1 (hnRNP D0) Binds And Destabilizes MRNA Pathway Diagram
Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies	Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram

Diseases associated with anti-PSMD13 antibody

Disease Name	Pubmed Publications
Weight Gain Antibodies	>1 publications with PSMD13 and Weight Gain
Inflammation Antibodies	>1 publications with PSMD13 and Inflammation

Organs/Tissues associated with anti-PSMD13 antibody

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>1 publications with PSMD13 and Muscle
Eye Antibodies	>1 publications with PSMD13 and Eye