Rabbit Anti-PSMD2 Polyclonal Antibody – Cat# MBS6338277

PSMD2 Antibody – Rabbit Polyclonal

Name: PSMD2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6338277
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6338277

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2… More details

$1060 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PSMD2, Polyclonal Antibody

Full Product Name

PSMD2, NT (PSMD2, TRAP2, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit RPN1, 26S proteasome regulatory subunit S2, 26S proteasome subunit p97, Protein 55.11, Tumor necrosis factor type 1 receptor-associated protein 2) (

Product Gene Name

anti-PSMD2 antibody

Product Synonym Names

PSMD2; TRAP2; 26S proteasome non-ATPase regulatory subunit 2; 26S proteasome regulatory subunit RPN1; 26S proteasome regulatory subunit S2; 26S proteasome subunit p97; Protein 55.11; Tumor necrosis factor type 1 receptor-associated protein 2

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

100,200 Da

Chromosome Location

Chromosome: 3; NC_000003.11 (184017022..184026840). Location: 3q27.1

OMIM

606223

3D Structure

ModBase 3D Structure for Q13200

Immunogen

PSMD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-35 amino acids from the N-terminal region of human PSMD2.

Conjugate

MaxLight490

Note

Preservative Free

Product Categories/Family for anti-PSMD2 antibody

Antibodies; Receptors

Applications Tested/Suitable for anti-PSMD2 antibody

Western Blot (WB), FLISA

Application Notes for anti-PSMD2 antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-PSMD2 antibody

Ikeda, Y., et al. J. Biol. Chem. 284(50):34889-34900(2009). Smith, L., et al. Neoplasia 11(11):1194-1207(2009). McCauley, J.L., et al. Genes Immun. 10(7):624-630(2009). Djakovic, S.N., et al. J. Biol. Chem. 284(39):26655-26665(2009). Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009).

Other Notes

Small volumes of anti-PSMD2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PSMD2 purchase

MBS6338277 is an antibody targeting PSMD2. Also known as PSMD2, NT (PSMD2, TRAP2, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit RPN1, 26S proteasome regulatory subunit S2, 26S proteasome subunit p97, Protein 55.11, Tumor necrosis factor type 1 receptor-associated protein 2) (. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PSMD2. It may not necessarily be applicable to this product.

NCBI GI #

25777602

NCBI GeneID

5708

NCBI Accession #

NP_002799.3

UniProt Primary Accession #

Q13200

UniProt Secondary Accession #

Q12932; Q15321; Q53XQ4; Q96I12

UniProt Related Accession #

Q13200

GenBank Nucleotide #

NM_002808.3

NCBI Official Full Name

26S proteasome non-ATPase regulatory subunit 2

NCBI Official Synonym Full Names

proteasome (prosome, macropain) 26S subunit, non-ATPase, 2

NCBI Official Symbol

PSMD2

NCBI Official Synonym Symbols

S2; P97; Rpn1; TRAP2

UniProt Protein Name

26S proteasome non-ATPase regulatory subunit 2

UniProt Synonym Protein Names

26S proteasome regulatory subunit RPN1; 26S proteasome regulatory subunit S2; 26S proteasome subunit p97; Protein 55.11; Tumor necrosis factor type 1 receptor-associated protein 2

Protein Family

26S proteasome non-ATPase regulatory

UniProt Gene Name

PSMD2

UniProt Synonym Gene Names

TRAP2

UniProt Entry Name

PSMD2_HUMAN

NCBI Protein Information

26S proteasome non-ATPase regulatory subunit 2; 55.11 protein; protein 55.11; TNFR-associated protein 2; 26S proteasome subunit p97; 26S proteasome regulatory subunit S2; 26S proteasome regulatory subunit RPN1; tumor necrosis factor receptor-associated pr

UniProt Comments for PSMD2

PSMD2: Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Belongs to the proteasome subunit S2 family.

Protein type: Cell cycle regulation; Proteasome complex

Chromosomal Location of Human Ortholog: 3q27.1

Cellular Component: proteasome complex; nucleoplasm; membrane; proteasome regulatory particle; cytosol

Molecular Function: protein binding; enzyme regulator activity

Biological Process: positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle; negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle; protein polyubiquitination; viral reproduction; apoptosis; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; regulation of apoptosis; antigen processing and presentation of peptide antigen via MHC class I; regulation of ubiquitin-protein ligase activity during mitotic cell cycle; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; gene expression; mitotic cell cycle; regulation of amino acid metabolic process; negative regulation of apoptosis; G1/S transition of mitotic cell cycle

Research Articles on PSMD2

1. Results suggest that PSMD2 may be a good molecular target candidate.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PSMD2 antibody

Reference Product	PubMed Publications
PSMC2 antibody	>2 publications with PSMD2 and PSMC2
TNFRSF1A antibody	>1 publications with PSMD2 and TNFRSF1A
PSMD5 antibody	>1 publications with PSMD2 and PSMD5
PSMC1 antibody	>1 publications with PSMD2 and PSMC1

Pathways associated with anti-PSMD2 antibody

Products by Pathway	Pathway Diagram
APC/C-mediated Degradation Of Cell Cycle Proteins Pathway antibodies	APC/C-mediated Degradation Of Cell Cycle Proteins Pathway Diagram
APC/C:Cdc20 Mediated Degradation Of Securin Pathway antibodies	APC/C:Cdc20 Mediated Degradation Of Securin Pathway Diagram
APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies	APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram
APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway antibodies	APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway Diagram
Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies	Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram
Activation Of NF-kappaB In B Cells Pathway antibodies	Activation Of NF-kappaB In B Cells Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Antigen Processing-Cross Presentation Pathway antibodies	Antigen Processing-Cross Presentation Pathway Diagram
Antigen Processing: Ubiquitination & Proteasome Degradation Pathway antibodies	Antigen Processing: Ubiquitination & Proteasome Degradation Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram

Diseases associated with anti-PSMD2 antibody

Disease Name	Pubmed Publications
Necrosis Antibodies	>17 publications with PSMD2 and Necrosis
Neoplasms Antibodies	>3 publications with PSMD2 and Neoplasms
Death Antibodies	>3 publications with PSMD2 and Death
Heart Diseases Antibodies	>1 publications with PSMD2 and Heart Diseases
Drug Toxicity Antibodies	>1 publications with PSMD2 and Drug Toxicity
Fibrosis Antibodies	>1 publications with PSMD2 and Fibrosis
Atrophy Antibodies	>1 publications with PSMD2 and Atrophy
Inflammation Antibodies	>1 publications with PSMD2 and Inflammation

Organs/Tissues associated with anti-PSMD2 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>2 publications with PSMD2 and Blood
Muscle Antibodies	>2 publications with PSMD2 and Muscle
Lung Antibodies	>2 publications with PSMD2 and Lung
Nerve Antibodies	>1 publications with PSMD2 and Nerve
Vascular Antibodies	>1 publications with PSMD2 and Vascular
Heart Antibodies	>1 publications with PSMD2 and Heart
Skin Antibodies	>1 publications with PSMD2 and Skin
Brain Antibodies	>1 publications with PSMD2 and Brain