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PSMG2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6338350

Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric… More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PSMG2, Polyclonal Antibody
Full Product Name
PSMG2, CT (PSMG2, HCCA3, PAC2, TNFSF5IP1, Proteasome assembly chaperone 2, Hepatocellular carcinoma-susceptibility protein 3, Tumor necrosis factor superfamily member 5-induced protein 1) (Biotin)
Product Gene Name
Product Synonym Names
PSMG2; HCCA3; PAC2; TNFSF5IP1; Proteasome assembly chaperone 2; Hepatocellular carcinoma-susceptibility protein 3; Tumor necrosis factor superfamily member 5-induced protein 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
264
OMIM
609702
3D Structure
ModBase 3D Structure for Q969U7
Immunogen
PSMG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224~253 amino acids from the C-terminal region of human PSMG2.
Conjugate
Biotin
Note
Preservative Free
Applications Tested/Suitable for anti-PSMG2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-PSMG2 antibody
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-PSMG2 antibody

Western blot analysis of PSMG2 Antibody (C-term) in MDA-MB468 cell line lysates (35ug/lane). PSMG2 (arrow) was detected using the purified Pab.
Rabbit Anti-PSMG2 Polyclonal Antibody – Cat# MBS6338350

Product References and Citations for anti-PSMG2 antibody

Cooper, J.D., et al. Nat. Genet. 40(12):1399-1401(2008). Barrett, J.C., et al. Nat. Genet. 40(8):955-962(2008). Miyagawa, H., et al. Rheumatology (Oxford) 47(2):158-164(2008). Parkes, M., et al. Nat. Genet. 39(7):830-832(2007).

Other Notes

Small volumes of anti-PSMG2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PSMG2 purchase

MBS6338350 is an antibody targeting PSMG2. Also known as PSMG2, CT (PSMG2, HCCA3, PAC2, TNFSF5IP1, Proteasome assembly chaperone 2, Hepatocellular carcinoma-susceptibility protein 3, Tumor necrosis factor superfamily member 5-induced protein 1) (Biotin). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PSMG2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Proteasome assembly chaperone 2
NCBI Official Synonym Full Names
proteasome (prosome, macropain) assembly chaperone 2
NCBI Official Symbol
PSMG2
NCBI Official Synonym Symbols
PAC2; HCCA3; CLAST3; MDS003; HsT1707; TNFSF5IP1
UniProt Protein Name
Proteasome assembly chaperone 2
UniProt Synonym Protein Names
Hepatocellular carcinoma-susceptibility protein 3; Tumor necrosis factor superfamily member 5-induced protein 1
UniProt Gene Name
PSMG2
UniProt Synonym Gene Names
PAC-2
UniProt Entry Name
PSMG2_HUMAN
NCBI Protein Information
proteasome assembly chaperone 2; PAC-2; PSMG2; HSPC260; HDCMC29P; x 003 protein; proteasome assembling chaperone 2; CD40 ligand-activated specific transcript 3; hepatocellular carcinoma susceptibility protein; hepatocellular carcinoma-susceptibility prote

UniProt Comments for PSMG2

PSMG2: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization. Belongs to the PSMG2 family.

Chromosomal Location of Human Ortholog: 18p11.21

Cellular Component: nucleus

Molecular Function: protein binding

Biological Process: mitotic cell cycle spindle assembly checkpoint; proteasome assembly; negative regulation of apoptosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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